Jennifer Rodenhouse - Seattle WA, US Antonio Pizzutelli - Seattle WA, US Jeff Fleischmann - Seattle WA, US Cyrus Kanga - Redmond WA, US Daniel Zurawski - Mercer Island WA, US
Assignee:
Microsoft Corporation - Redmond WA
International Classification:
1402
US Classification:
D14486
Murine Wound Model For Testing Pathogen Viruence And Therapeutic Efficacy
Rebecca L. Pavlicek - Bremerton WA, US Daniel V. Zurawski - New Market MD, US Mitchell G. Thompson - Washington DC, US Chad C. Black - Knokville TN, US
International Classification:
A61K 49/00 G01N 33/50 C12Q 1/68
Abstract:
The invention provides a murine model of wound infection and biofilm formation and methods for producing such model. The inventive murine model of wound infection may be used to evaluate pathogen virulence and test efficacy of a pharmaceutical composition and/or a treatment procedures in preventing or treating wound infection, reducing biofilm formation, or reducing symptoms in a subject.