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Lalit N Goswami

age ~45

from Columbia, MO

Lalit Goswami Phones & Addresses

  • Columbia, MO
  • Amherst, NY
  • 161 Princeton Ave, Buffalo, NY 14226 • 7168629573
  • Boynton, MO

Us Patents

  • Water Soluble Tetrapyrollic Photosensitizers For Photodynamic Therapy

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  • US Patent:
    7820143, Oct 26, 2010
  • Filed:
    Feb 19, 2009
  • Appl. No.:
    12/378751
  • Inventors:
    Ravindra K. Pandey - Williamsville NY, US
    Amy Gryshuk - Pleasanton CA, US
    Lalit Goswami - Amherst NY, US
    William Potter - Grand Island NY, US
    Allan Oseroff - Buffalo NY, US
  • Assignee:
    Health Research, Inc. - Buffalo NY
  • International Classification:
    A61B 5/055
  • US Classification:
    424 93, 424 961, 514279, 514410
  • Abstract:
    A tetrapyrollic photosensitizer compound having at least one pendant —CHCHCON(CHCON(CHCOOH))or —N(CHCOOH)group or esters thereof said tetrapyrollic compound being a chlorin, bacteriochlorin, porphyrin, pyropheophorbide, purpurinimide, or bacteriopurpurinimide. Desirably the compound has the formula:.
  • Multi Dtpa Conjugated Tetrapyrollic Compounds For Phototherapeutic Contrast Agents

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  • US Patent:
    7897140, Mar 1, 2011
  • Filed:
    Jun 30, 2006
  • Appl. No.:
    11/479524
  • Inventors:
    Ravindra K. Pandey - Williamsville NY, US
    Lalit Goswami - Amherst NY, US
    Joseph Spernyak - West Seneca NY, US
    Peter Kanter - East Aurora NY, US
    Richard Mazurchuk - Clarence Center NY, US
  • Assignee:
    Health Research, Inc. - Buffalo NY
  • International Classification:
    A61K 5/055
  • US Classification:
    424 9362, 424 93, 424 936, 424 9361, 424 9363, 424 9364, 424 9365, 424 165, 424 111, 424 91, 540121
  • Abstract:
    Novel tetrapyrollic water soluble photosensitizing and imaging compounds and the methods of treating and imaging hyperproliferative tissue, e. g. tumors and hypervacularized tissue such as found in macular degeneration. Broadly, the compounds are tetrapyrollic photosensitizer compounds where the tetrapyrollic compound is a chlorin, bacteriochlorin, porphyrin, pyropheophorbide, purpurinimide, or bacteriopurpurinimide having 3 to 6 —CHCONHphenylCHCH(N(CHCOOH)))(CHN(CHCOOH)(CHCHN(CHCOOH))) groups or esters thereof or complexes thereof with gadolinium(III).
  • Water Soluble Tetrapyrollic Photosensitizers For Photodynamic Therapy

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  • US Patent:
    20070149497, Jun 28, 2007
  • Filed:
    Jun 14, 2006
  • Appl. No.:
    11/452511
  • Inventors:
    Ravindra Pandey - Williamsville NY, US
    Amy Gryshuk - Pleasanton CA, US
    Lalit Goswami - Amherst NY, US
    William Potter - Grand Island NY, US
    Allan Oseroff - Buffalo NY, US
  • Assignee:
    Health Research, Inc. - Buffalo NY
  • International Classification:
    A61K 31/555
    C07D 487/22
    A61K 31/409
  • US Classification:
    514185000, 540145000, 514410000
  • Abstract:
    A tetrapyrollic photosensitizer compound having at least one pendant —CHCHCON(CHCON(CHCOOH))or —N(CHCOOH)group or esters thereof said tetrapyrollic compound being a chlorin, bacteriochlorin, porphyrin, pyropheophorbide, purpurinimide, or bacteriopurpurinimide. Desirably the compound has the formula: or a pharmaceutically acceptable derivative thereof, wherein R-Rand Rare various substituents and Ris substituted or unsubstituted —CHCHCON(CHCON(CHCOOH)); or —N(CHCOOH). The invention also includes a method of treatment by photodynamic therapy by treatment with light after injecting the compound and a method of imaging by fluorescence after injection of the compound.
  • Water Soluble Tetrapyrollic Photosensitizers For Photodynamic Therapy

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  • US Patent:
    20110091390, Apr 21, 2011
  • Filed:
    Oct 26, 2010
  • Appl. No.:
    12/912033
  • Inventors:
    Ravindra K. Pandey - Williamsville NY, US
    Amy Gryshuk - Pleasanton CA, US
    Lalit Goswami - Amherst NY, US
    William Potter - Grand Island NY, US
    Allan Oseroff - Buffalo NY, US
  • Assignee:
    Health Research, Inc. - Buffalo NY
  • International Classification:
    A61K 49/00
    A61P 35/00
  • US Classification:
    424 961, 424 96
  • Abstract:
    A tetrapyrollic photosensitizer compound having at least one pendant —CHCHCON(CHCON(CHCOOH))or —N(CHCOOH)group or esters thereof said tetrapyrollic compound being a chlorin, bacteriochlorin, porphyrin, pyropheophorbide, purpurinimide, or bacteriopurpurinimide. Desirably the compound has the formula:or a pharmaceutically acceptable derivative thereof, wherein R—Rand Rare various substituents and Ris substituted or unsubstituted —CHCHCON(CHCON(CHCOOH)); or —N(CHCOOH). The invention also includes a method of treatment by photodynamic therapy by treatment with light after injecting the compound and a method of imaging by fluorescence after injection of the compound.
  • Multimodality Agents For Tumor Imaging And Therapy

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  • US Patent:
    20110223102, Sep 15, 2011
  • Filed:
    Sep 11, 2008
  • Appl. No.:
    12/677381
  • Inventors:
    Ravindra K. Pandey - Williamsville NY, US
    Suresh Pandey - Buffalo NY, US
    Lalit Goswami - Columbia MO, US
    Allan Oseroff - Buffalo NY, US
    Shipra Dubey - Williamsville NY, US
    Munawwar Sajjad - Clarence Center NY, US
    Stephanie Pincus - Buffalo NY, US
  • Assignee:
    HEALTH RESEARCH, INC. - Buffalo NY
    THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK - Amherst NY
  • International Classification:
    A61K 51/04
    A61K 49/00
    A61K 31/30
    A61K 31/409
    A61K 38/12
    A61K 31/437
    A61K 31/506
    A61P 35/00
    A61P 43/00
  • US Classification:
    424 111, 424 91, 514499, 514410, 514 199, 514279, 514275
  • Abstract:
    A compound that is a conjugate of an antagonist to an integrin expressed by a tumor cell and at least one of a tumor avid tetrapyrollic photosensitizer, a fluorescent dye, and a radioisotope labeled moiety wherein the radioisotope is C, F, Cu, I, Tc, In or GdIII and its method of use for diagnosing, imaging and/or treating hyperproliferative tissue such as tumors. Preferably the photosensitizer is a tumor avid tetrapyrollic photosensitizer, e.g. a porphyrin, chlorin or bacteriochlorin, e.g. pheophorbides and pyropheophorbides. Such conjugates have extreme tumor avidity and can be used to inhibit or completely destroy the tumor by light absoption. The integrin is usually αvβ3, α5β1, αvβ5, α4β1, or α2β1. Preferably, the antagonist is an RGD peptide or another antagonist that may be synthetic such as a 4-{2-(3,4,5,6-tetra-hydropyrimidin-2-ylamino)ethyloxy}-benzoyl]amino-2-(S)-amino-ethyl-sulfonylamino group. Such compounds provide tumor avidity and imaging ability thus permitting selective and clear tumor imaging.
  • Silica Nanoparticles Postloaded With Photosensitizers For Drug Delivery In Photodynamic Therapy

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  • US Patent:
    20110288234, Nov 24, 2011
  • Filed:
    Feb 19, 2009
  • Appl. No.:
    12/918232
  • Inventors:
    Ravindra K. Pandey - Williamsville NY, US
    Lalit N. Goswami - Columbia MO, US
    Allan Oseroff - Buffalo NY, US
    Stephanie Pincus - Buffalo NY, US
    Janet Morgan - Buffalo NY, US
    Paras N. Prasad - Williamsville NY, US
    Earl J. Bergey - South Dayton NY, US
  • Assignee:
    The Research Foundation on State University of NY - Amherst NY
    Health Research, Inc. - Buffalo NY
  • International Classification:
    C08G 77/38
    C08F 130/08
    C08G 77/388
    B82Y 5/00
  • US Classification:
    525 541, 525474, 525 542, 5253265, 977773, 977788, 977906, 977927, 977897, 977930, 977928
  • Abstract:
    A nanoparticle including a polysiloxane base having an exterior surface and having a photosensitizer at least partly exposed at its exterior surface, said photosensitizer being secured to the exterior surface by loading the photosensitizer onto the surface after formation of the polysiloxane base of the nanoparticle. The nanoparticle may have tumor targeting moieties and may be post loaded with cyanine dye. The nanoparticle preferably includes post loaded moieties providing at least two of tumor specificity, photodynamic properties and imaging capabilities and the photosensitizer is tagged with a radioisotope. A method for preparation of the nanoparticle is also provided.
  • Multimodality Agents For Tumor Imaging And Therapy

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  • US Patent:
    20130237688, Sep 12, 2013
  • Filed:
    Apr 15, 2013
  • Appl. No.:
    13/863145
  • Inventors:
    Lalit Goswami - Columbia MO, US
    Allan Oseroff - Buffalo NY, US
    Shipra Dubey - Williamsville NY, US
    Munawwar Sajjad - Clarence Center NY, US
  • Assignee:
    The Research Foundation of State University of New York - Amherst NY
    Health Research, Inc. - Buffalo NY
  • International Classification:
    C07K 7/06
  • US Classification:
    530330
  • Abstract:
    A compound that is a conjugate of an antagonist to an integrin expressed by a tumor cell and at least one of a tumor avid tetrapyrollic photosensitizer, a fluorescent dye, and a radioisotope labeled moiety wherein the radioisotope is C, F, Cu, I, Tc, In or GdIII and its method of use for diagnosing, imaging and/or treating hyperproliferative tissue such as tumors. Preferably the photosensitizer is a tumor avid tetrapyrollic photosensitizer, e.g. a porphyrin, chlorin or bacteriochlorin, e.g. pheophorbides and pyropheophorbides. Such conjugates have extreme tumor avidity and can be used to inhibit or completely destroy the tumor by light absorption. The integrin is usually αvβ3, α5β1, αvβ5, α4β1, or α2β1. Preferably, the antagonist is an RGD peptide or another antagonist that may be synthetic such as a 4-{2-(3,4,5,6-tetra-hydropyrimidin-2-ylamino)ethyloxy}-benzoyl]amino-2-(S)-amino-ethyl-sulfonylamino group. Such compounds provide tumor avidity and imaging ability thus permitting selective and clear tumor imaging.
  • Neuromuscular Blocking Agents

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  • US Patent:
    20210047289, Feb 18, 2021
  • Filed:
    Mar 27, 2019
  • Appl. No.:
    15/733705
  • Inventors:
    - Columbia MO, US
    Lalit N. Goswami - Columbia MO, US
    Marion F Hawthorne - Columbia MO, US
    Satish S. Jalisatgi - Columbia MO, US
  • International Classification:
    C07D 401/08
    C07C 211/63
    A61P 21/00
  • Abstract:
    Disclosed herein are carborane derivatives of Formula I or Formula V, or a pharmaceutically acceptable salt thereof, for use as neuromuscular blocking agents. The carborane is substituted with two cationic functional groups selected from amines that form ammonium cations, ethers and/or alcohols that form oxonium cations, sulfides and/or thiols that form sulfonium cations, and phosphanes and/or phosphines that form phosphonium cations.

Resumes

Lalit Goswami Photo 1

Senior Scientist-Bioanalytical

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Location:
Washington, DC
Industry:
Pharmaceuticals
Work:
Boehringer Ingelheim
Senior Scientist-Bioanalytical

Merial, A Sanofi Company 2015 - Dec 2016
Senior Scientist-I

University of Missouri 2010 - 2015
Group Leader-Biomedical Synthesis

University of Missouri 2007 - 2010
Senior Postdoctoral Fellow

University at Buffalo 2006 - 2007
Postdoctoral Fellow-Part Time
Education:
Central Drug Research Institute (Cdri) Lucknow, India 1999 - 2004
Doctorates, Doctor of Philosophy, Philosophy, Chemistry
Kumaun University 1997 - 1999
Master of Science, Masters, Chemistry
Kumaun University 1994 - 1997
Bachelors, Biology, Chemistry
Central Drug Research Institute (Cdri) Lucknow
Skills:
Drug Discovery
Characterization
Purification
Organic Chemistry
Organic Synthesis
Analytical Chemistry
Chemistry
Fluorescence
Nanoparticles
Medicinal Chemistry
Drug Design
Formulation
Hplc
Diagnostic Imaging Probes For Optical/Mri/Ct/X Ray/Pet
Mri
Contrast Agents
Multimodality Imaging Probes
Biosensors
Heterocyclic Chemistry
Heterobifunctional Linkers
Amino Acids and Peptides
Theranostic Agents
Nanomedicine
Drug Delivery
Bioconjugate Chemistry
Targeted Drug Delivery
Dendrimers Polymers Liposomes
Synthetic Methadology
Cancer
Polymers
Science
High Performance Liquid Chromatography
Bioanalysis
Liquid Chromatography Mass Spectrometry
Analytical Method Validation
Good Laboratory Practice
Lcms
Nuclear Magnetic Resonance
Pharmacokinetics
Fda Cvm
Languages:
English
Hindi
Certifications:
Advance Lcms Troubleshooting Training Certificate-2017
Bio Safety Officer Certificate-2017
Solid-Phase Microextraction (Spme) Training Certificate-2016
Watson-Lims
Lalit Goswami Photo 2

As A Lecturer

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Work:
Shree Ji Goverdhan Maharaj Professional Studies
As A Lecturer
Lalit Goswami Photo 3

Lalit Goswami

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Lalit Goswami Photo 4

Lalit Goswami Columbia, MO

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Work:
I2NM2, University of Missouri (MU)

Sep 2010 to 2000
Group Leader
I2NM2, University of Missouri (MU)

Feb 2010 to 2000
Research Assistant Professor
I2NM2, MU
Columbia, MO
Jul 2007 to Jan 2010
Research Associate
SUNY at Buffalo (UB)
Buffalo, NY
Feb 2006 to Jun 2007
Post-doctoral fellow-Part time
Roswell Park Cancer Institute (RPCI)
Buffalo, NY
Jul 2004 to Jun 2007
Post-doctoral fellow
Education:
Central Drug Research Institute
Lucknow, Uttar Pradesh
2004
Ph.D. in Medicinal/Synthetic Organic Chemistry
Kumaun University-Nainital
Naini Tal, Uttarakhand
1999
MS in Chemistry
Kumaun University-Nainital
Naini Tal, Uttarakhand
1997
BS in Chemistry-Biology
Lalit Goswami Photo 5

Lalit Goswami

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Lalit Goswami Photo 6

Lalit Goswami Columbia, MO

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Work:
I2NM2, University of Missouri (MU)

Sep 2010 to 2000
Group Leader
I2NM2, University of Missouri (MU)

Feb 2010 to 2000
Research Assistant Professor
I2NM2, MU
Columbia, MO
Jul 2007 to Jan 2010
Research Associate
SUNY at Buffalo (UB)
Buffalo, NY
Feb 2006 to Jun 2007
Post-doctoral fellow-Part time
Roswell Park Cancer Institute (RPCI)
Buffalo, NY
Jul 2004 to Jun 2007
Post-doctoral fellow
Education:
Central Drug Research Institute
Lucknow, Uttar Pradesh
2004
Ph.D. in Medicinal/Synthetic Organic Chemistry
Kumaun University-Nainital
Naini Tal, Uttarakhand
1999
MS in Chemistry
Kumaun University-Nainital
Naini Tal, Uttarakhand
1997
BS in Chemistry-Biology
Lalit Goswami Photo 7

Lalit Goswami

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Googleplus

Lalit Goswami Photo 8

Lalit Goswami

Work:
Utsav Honda - Asst. Sales Manager
Lalit Goswami Photo 9

Lalit Goswami

Tagline:
Stay silence,Ur wrk w'll say ev'thing.
Lalit Goswami Photo 10

Lalit Goswami

Lalit Goswami Photo 11

Lalit Goswami

Lalit Goswami Photo 12

Lalit Goswami

Lalit Goswami Photo 13

Lalit Goswami

Lalit Goswami Photo 14

Lalit Goswami

Lalit Goswami Photo 15

Lalit Goswami

Facebook

Lalit Goswami Photo 16

Lalit Goswami

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Lalit Goswami Photo 17

Lalit Goswami

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Lalit Goswami Photo 18

Lalit Goswami

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Lalit Goswami

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Lalit Goswami

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Lalit Goswami

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Lalit Goswami

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Lalit Goswami

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Youtube

Raag Lalit, Ustad Rashid Khan, Pandit Bharat ...

Vocal : Ustad Rashid Khan, Sarangi : Pandit Bharat Bhushan Goswami

  • Category:
    Music
  • Uploaded:
    23 May, 2010
  • Duration:
    7m 5s

Australia's Michael Clarke pulls out of IPL; ...

Australian vice-captain Michael Clarke has pulled out from the second ...

  • Category:
    Sports
  • Uploaded:
    05 Feb, 2009
  • Duration:
    35s

Pt Anoop Misra Raag Lalit Part 2 Banaras Ghar...

Anoop Misra disciple of one of the legend vocalist of banaras "Late Pt...

  • Category:
    Music
  • Uploaded:
    30 Jul, 2009
  • Duration:
    8m 24s

Raag Lalit ab to aja dil ke

Ustad Fateh Ali Khan from the Patiala Gharana.

  • Category:
    Music
  • Uploaded:
    13 Nov, 2009
  • Duration:
    6m 57s

Gurudeva at Rupa Goswami Samadhi Eng. Sp. Subs

Date =20080813 Srila Gurudeva speaking on the disappearance of Srila R...

  • Category:
    Education
  • Uploaded:
    27 Jul, 2011
  • Duration:
    17m 33s

Is the IPL murk limited to two men? Check out...

Who is covering up the great IPL mess? Both Shashi Tharoor & Lalit Mod...

  • Category:
    News & Politics
  • Uploaded:
    22 Apr, 2010
  • Duration:
    7m 13s

Lalit Modi: "Don't Blame IPL For Injuries"

  • Category:
    Sports
  • Uploaded:
    02 Jun, 2009
  • Duration:
    1m 19s

Are both Shashi Tharoor & Lalit Modi at fault...

WATCH an exclusive video from the Times Now Debate show as the panelis...

  • Category:
    News & Politics
  • Uploaded:
    15 Apr, 2010
  • Duration:
    8m 42s

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