Ali Hassan - Mountain View CA, US Lester John Lloyd - Orinda CA, US Michael Orth - Los Gatos CA, US Mark Yang - Los Gatos CA, US Binh Luong - Los Gatos CA, US Brian K. Courtney - Toronto, CA Peter J. Fitzgerald - Portola Valley CA, US
Methods and devices for selectively removing an agent from a physiological site, e. g. , a physiological efferent fluid collection site, are provided. Aspects of the invention include fluid removal (e. g. , aspiration) devices having a fluid removal element and a flow modulator positioned at a distal end of the fluid removal element. The flow modulator is configured to converge intersecting fluid flow paths into the fluid removal element. Also provided are systems and kits for performing the subject methods. The subject invention finds use in a variety of different applications, including the selective removal of both therapeutic and diagnostic agents from a variety of different physiological sites.
Methods And Systems For Filtering Aspirated Materials
Thomas Goff - Menlo Park CA, US Mark Yang - San Francisco CA, US Michael Orth - Morgan Hill CA, US Gary Hulme - San Jose CA, US John MacMahon - Mountain View CA, US
Assignee:
KERBEROS PROXIMAL SOLUTIONS, INC. - Cupertino CA
International Classification:
A61M 31/00 A61M 37/00
US Classification:
604093010, 604506000
Abstract:
Solid materials are separated from hollow body structure aspirates using a filter assembly disposed between an aspiration catheter and an aspirate receptacle. Filter elements having different pore or mesh sizes may be used to size classify the separated solid materials. Multiple filter assemblies may be disposed in parallel or series between the aspiration catheter and aspirate receptacle to provide for different levels of size classification.
Thomas Goff - Menlo Park CA, US Michael Orth - Morgan Hill CA, US Mark Yang - San Francisco CA, US Hung Ha - San Jose CA, US
Assignee:
KERBEROS PROXIMAL SOLUTIONS, INC. - Cupertino CA
International Classification:
A61M 1/00
US Classification:
604118000, 604043000, 604528000
Abstract:
An aspiration catheter comprises a catheter body having an aspiration lumen therethrough. The distal opening of the aspiration lumen can be modified in various ways or can have the addition of structure in order to disrupt sealing between the port and material being aspirated. Examples of modifications include slots, castellations, zig-zag features, and other geometries which resist sealing of aspirated material. Blades, rollers, vibrating elements, and other structures may be provided within or around the distal end of the aspiration lumen in order to dislodge and disrupt aspirated material which can seal against the opening.
Methods And Devices For Endovascular Introduction Of An Agent
Ali H. Hassan - Palo Alto CA, US Brian K. Courtney - Toronto, CA Mark Yang - Los Gatos CA, US Peter J. Fitzgerald - Portola Valley CA, US Binh Luong - Los Gatos CA, US Michael Orth - Los Gatos CA, US
International Classification:
A61M 25/14 A61B 6/00 A61M 1/00
US Classification:
600433, 604500, 604503, 604523
Abstract:
Methods and devices for introduction of an agent to a vascular physiological site are provided. Aspects of the methods include employing an agent delivery device and an aspiration device to introduce and remove agent from a vascular site in a manner sufficient to minimize agent loss. Also provided are systems and kits for performing the subject methods. The subject invention finds use in a variety of different applications.
Methods And Devices For Removal Of A Medical Agent From A Physiological Efferent Fluid Collection Site
Lester John Lloyd - Orinda CA, US Michael Orth - Los Gatos CA, US Mark Yang - Los Gatos CA, US Binh Luong - Los Gatos CA, US Brian K. Courtney - Toronto, CA Peter J. Fitzgerald - Portola Valley CA, US
Assignee:
Catharos Medical Systems, Inc. - Campbell CA
International Classification:
A61M 1/00
US Classification:
604319
Abstract:
Methods and devices for selectively removing an agent from a physiological site, e.g., a physiological efferent fluid collection site, are provided. Aspects of the invention include fluid removal (e.g., aspiration) devices having a fluid removal element and a flow modulator positioned at a distal end of the fluid removal element. The flow modulator is configured to converge intersecting fluid flow paths into the fluid removal element. Also provided are systems and kits for performing the subject methods. The subject invention finds use in a variety of different applications, including the selective removal of both therapeutic and diagnostic agents from a variety of different physiological sites.
Catheter Apparatus With Telescoping Lumen Catheters And Its Use In Methods For Treating Vasculatures
Mehrdad Farhangnia - San Francisco CA, US Mark C. Yang - San Francisco CA, US Mark Taber - St. Louis MO, US
International Classification:
A61M 25/09
US Classification:
604510, 604528
Abstract:
The invention provides for methods and catheter apparatus for passing one or more guidewires (via the use of one or more telescoping guidewire lumens) through a chronic total occlusion of a vasculature. The catheter apparatus may include: a catheter shaft having a distal end; one or more telescoping guidewire lumen catheters passing longitudinally through the shaft, wherein the one or more guidewire lumen catheters are capable of telescoping beyond the distal end of the catheter shaft; an expansible distal portion of the shaft; and a retractable sheath covering at least a portion of the expansible distal portion of the shaft, wherein retracting the retractable sheath from the expansible distal portion of the shaft directly activates the expansible distal portion of the shaft causing expansion of the expansible distal portion of the shaft.
Catheter Apparatus With Telescoping Lumen Catheters And Its Use In Methods For Treating Vasculatures
- Redwood City CA, US Mark C. Yang - San Francisco CA, US Mark Taber - St. Louis MO, US
Assignee:
Roxwood Medical, Inc. - Redwood City CA
International Classification:
A61M 25/09
Abstract:
The invention provides for methods and catheter apparatus for passing one or more guidewires (via the use of one or more telescoping guidewire lumens) through a chronic total occlusion of a vasculature. The catheter apparatus may include: a catheter shaft having a distal end; one or more telescoping guidewire lumen catheters passing longitudinally through the shaft, wherein the one or more guidewire lumen catheters are capable of telescoping beyond the distal end of the catheter shaft; an expansible distal portion of the shaft; and a retractable sheath covering at least a portion of the expansible distal portion of the shaft, wherein retracting the retractable sheath from the expansible distal portion of the shaft directly activates the expansible distal portion of the shaft causing expansion of the expansible distal portion of the shaft.
Method And Apparatus For Centering A Microcatheter Within A Vasculature
- REDWOOD CITY CA, US Mark TABER - St. Louis MO, US Mark C. YANG - San Francisco CA, US
Assignee:
ROXWOOD MEDICAL, INC. - REDWOOD CITY CA
International Classification:
A61B 17/3207 A61B 17/34
Abstract:
The invention is directed to methods and apparatus for centering a microcatheter within a vasculature. In one aspect, the methods and apparatus can be used to support centering and to facilitate a guidewire to cross through a chronic total occlusion. In one embodiment, the catheter apparatus includes: a microcatheter having a lumen, a distal opening and a distal end; one or more guidewires for passing through the lumen of the microcatheter; an inner shaft having a lumen, a distal opening and a distal end for passing the inner shaft over the microcatheter; an outer shaft having a lumen, a distal opening and a distal end for passing the outer shaft over the inner shaft; and a self-expandable scaffold structure disposed towards the distal end of the inner shaft. The self-expandable scaffold structure is preferably non-occluding thereby allowing blood to flow through the scaffold. Preferably, the inner shaft and microcatheter are capable of being independently operable.