Adel A Mikhail

US Patent:

44041004, Sep 13, 1983

Filed:

May 5, 1982

Appl. No.:

6/374973

Inventors:

Adel A. Mikhail - Bloomington MN

Assignee:

Medical Incorporated - Inver Grove Heights MN

International Classification:

B01D 3100

US Classification:

210232

Abstract:

A hemodialyzer having a reinforced blood side case half and a reinforced dialysate side case half, said case halves having generally trapezoidal cross sections with the longer sides being open and joinable together in the assembled form along a parting line. Wedge elements extending within said case halves positioned with their apexes at said parting line. The base walls of the wedges and case halves define together a generally rectangular cavity in which a stack of pleated cofolded semipermeable membrane and dialysate permeable separator is positioned. The last pleat of the membrane on either side of the stack extends over the end of the adjacent wedge element on the blood side and is trapped and adhesively sealed between the side walls of the blood side case half and the coextending wall of the wedge element. The dialysate side of the stack is sealed to the base wall of the dialysate side case half by a non-adherent solid preformed body of resilient elastomeric material. The coextending wedge element and case half sides are contoured so as to permit accurate measurement and positioning of initially flowable curable in situ adhesive.

US Patent:

57073570, Jan 13, 1998

Filed:

Feb 22, 1996

Appl. No.:

8/605435

Inventors:

Adel A. Mikhail - Bloomington MN
Gene E. Stobbs - Brooklyn Park MN
Adel M. Hashw - Brooklyn Park MN
Shelley N. Johnson - Minnetonka MN

Assignee:

C V Dynamics, Inc. - Inver Grove Heights MN

International Classification:

A61M 2500

US Classification:

604 96

Abstract:

An indwelling urinary catheter having a palpitatable multiaxial dome-type valve and an inflatable anchoring balloon. The valve has a peripheral trough to maximize drainage. The catheter body and balloon are integrally molded from silicone to produce a uniform and symmetrical balloon shape. The balloon shape may be selectively altered by varying bonding patterns or wall thicknesses. Valve openings traverse an arcuate pathway, and adjacent valve elements are separated by an intermediate rib to ensure a reliable closure. Valve elements are readily displaced by a drainage tube connector that engages the valve body. A collar on the catheter body moves axially along helical threads to adjust tension on the balloon.

US Patent:

60509341, Apr 18, 2000

Filed:

Feb 25, 1998

Appl. No.:

9/030132

Inventors:

Adel A. Mikhail - Bloomington MN
Gene E. Stobbs - Brooklyn Park MN
Adel M. Hashw - Eden Prairie MN
Shelley N. Johnson - Minnetonka MN

Assignee:

CV Dynamics, Inc. - Inver Grove Heights MN

International Classification:

A61F 200

US Classification:

600 30

Abstract:

An indwelling urinary catheter having a palpitatable multi-axial dome-type discharge valve with protective shoulders. The protective shoulders are preferably raised above other unprotected portions of an outer surface of the valve. In preferred embodiments, the valve wall is made substantially of a first material and each of the protective shoulders include an elongated thickness of a second material which is more rigid than the first material. The valve has a peripheral trough to maximize drainage. Valve openings traverse an arcuate pathway, and adjacent valve elements are separated by an intermediate rib to ensure a reliable closure.

US Patent:

56243952, Apr 29, 1997

Filed:

Oct 20, 1995

Appl. No.:

8/546572

Inventors:

Adel A. Mikhail - Bloomington MN
Gene E. Stobbs - Brooklyn Park MN
Adel M. Hashw - Brooklyn Park MN
Shelley N. Johnson - Minnetonka MN

Assignee:

CV Dynamics, Inc. - Inver Grove Heights MN

International Classification:

A61M 1100

US Classification:

604 93

Abstract:

An indwelling urinary catheter having a palpitatable multiaxial dome-type valve and an inflatable anchoring balloon. The valve has a peripheral trough to maximize drainage. The catheter body and balloon are integrally molded from silicone to produce a uniform and symmetrical balloon shape. The balloon shape may be selectively altered by varying bonding patterns or wall thicknesses. Valve openings traverse an arcuate pathway, and adjacent valve elements are separated by an intermediate rib to ensure a reliable closure. Valve elements are readily displaced by a drainage tube connector that engages the valve body. A collar on the catheter body moves axially along helical threads to adjust tension on the balloon.

US Patent:

58240624, Oct 20, 1998

Filed:

Mar 29, 1996

Appl. No.:

8/626170

Inventors:

Nandkishor G. Patke - Shoreview MN
Adel A. Mikhail - Bloomington MN
Gene E. Stobbs - Brooklyn Park MN
Shelley N. Johnson - Minnetonka MN

Assignee:

CV Dynamics, Inc. - Inver Grove Heights MN

International Classification:

A61F 224

US Classification:

623 2

Abstract:

A bileaflet heart valve comprising an annular base and pivoting leaflets. Each leaflet if "free-floating" within recesses without fixed rotational axis, to increase translational movement and redistribute stresses. Each recess fluidly communicates with a groove extending at least partially around the inner surface of the annular base and flow is directed through the recesses at different angles during antegrade circulation, retrograde circulation, and valve closure. A recess entrance angle to each of the recesses preferably being less than about 35. degree. and the pivoting mechanism within the recess including first and second fulcrum edges of each leaflet shiftably engaged with side surfaces of the respective recess. The leaflets have a beveled bottom surface having two separate planar surfaces which lie at an angle to one another. In preferred embodiments, a central region of each leaflet is spaced apart from the annular base when the leaflet is in a fully closed position to minimize cavitation.

US Patent:

61835110, Feb 6, 2001

Filed:

Oct 2, 1998

Appl. No.:

9/165442

Inventors:

Nandkishor G. Patke - Shoreview MN
Adel A. Mikhail - Bloomington MN
Gene E. Stobbs - Brooklyn Park MN

Assignee:

CV Dynamics, Inc. - Inver Grove Heights MN

International Classification:

A61F 224

US Classification:

623 228

Abstract:

A bileaflet heart valve comprising an annular base and pivoting leaflets. Each leaflet is "free-floating" within recesses without fixed rotational axis in order to increase translational movement and redistribute stresses. Each recess fluidly communicates with a groove extending at least partially around the inner surface of the annular base and fluid flow is directed through the recesses at different angles during antegrade circulation, retrograde circulation, and valve closure. A recess entrance angle to each of the recesses preferably being less than about 35. degree. and the pivoting mechanism within the recess including first and second fulcrum edges of each leaflet shiftably engaged with side surfaces of the respective recesses. The leaflets have a beveled bottom side having two separate planar surfaces which lie at an angle to one another. In preferred embodiments, an upper planar surface of the bottom surface of each leaflet lies at an angle of greater than ninety (90) degrees with respect to a horizontal passing through a section of the annular base when the leaflet is in a fully open position.

US Patent:

62966634, Oct 2, 2001

Filed:

Apr 5, 1999

Appl. No.:

9/286161

Inventors:

Nandkishor G. Patke - Shoreview MN
Adel A. Mikhail - Bloomington MN
Gene E. Stobbs - Brooklyn Park MN

Assignee:

Medical CV, Inc. - Inver Grove Heights MN

International Classification:

A61F 224

US Classification:

623 228

Abstract:

A bileaflet heart valve comprising an annular base and pivoting leaflets. Each leaflet is "free-floating" within recesses without fixed rotational axis in order to increase translational movement and redistribute stresses. Each recess fluidly communicates with a groove extending at least partially around the inner surface of the annular base and fluid flow is directed through the recesses at different angles during antegrade circulation, retograde circulation, and valve closure. A recess entrance angle to each of the recesses in certain embodiments is preferably less than about 35. degree. and the pivoting mechanism within each recess includes first and second fulcrum edges of each leaflet shiftably engaged with side surfaces of the respective recesses. The leaflets have a beveled bottom side having two separate planar surfaces which lie at an angle to one another. In certain embodiments, an up planar surface of the bottom surface of each leaflet lies at an angle of greater than ninety (90) degrees with respect to a horizontal plane passing through a horizontal cross-section of the annular base when the leaflet is in a fully open position.