Alexander Laskin

US Patent:

20110220784, Sep 15, 2011

Filed:

Mar 11, 2010

Appl. No.:

12/722257

Inventors:

Patrick J. Roach - Kennewick WA, US
Julia Laskin - Richland WA, US
Alexander Laskin - Richland WA, US

Assignee:

BATTELLE MEMORIAL INSTITUTE - Richland WA

International Classification:

H01J 49/04
H01J 49/26

US Classification:

250282, 250288

Abstract:

An apparatus and process are disclosed that deliver an analyte deposited on a substrate to a mass spectrometer that provides for trace analysis of complex organic analytes. Analytes are probed using a small droplet of solvent that is formed at the junction between two capillaries. A supply capillary maintains the droplet of solvent on the substrate; a collection capillary collects analyte desorbed from the surface and emits analyte ions as a focused spray to the inlet of a mass spectrometer for analysis. The invention enables efficient separation of desorption and ionization events, providing enhanced control over transport and ionization of the analyte.