Danyi Zhang - Berwyn PA, US Xu Meng - Audubon PA, US Alvin Kotake - Radnor PA, US
Assignee:
Wyeth - Madison NJ
International Classification:
A61K031/5377 A61K031/4439 A61K031/405
US Classification:
514/232800, 514/339000, 514/414000, 514/415000
Abstract:
This invention relates to pharmaceutical compositions and methods of treatment utilizing a PTPase (protein-tyrosine phosphatase) inhibitors and an angiotensin converting enzyme (ACE) inhibitor to lower the risk of cardiovascular disease and cardiovascular events in a mammal experiencing or subject to type II diabetes in mammals experiencing or subject to type II diabetes (non-insulin-dependent diabetes mellitus), preferably in human type II diabetics, or Syndrome X.