Ani B Sarkahian

US Patent:

54440416, Aug 22, 1995

Filed:

May 20, 1992

Appl. No.:

7/885202

Inventors:

Albert J. Owen - West Chester PA
Seang H. Yiv - Wilmington DE
Ani B. Sarkahian - Bryn Mawr PA

Assignee:

Ibah, Inc. - Blue Bell PA

International Classification:

A61K 9107
A61K 3800
A61K 3816
A61K 3900

US Classification:

514 2

Abstract:

There is provided a water-in-oil (w/o) microemulsion which readily converts to an oil-in-water (o/w) emulsion by the addition of aqueous fluid to the w/o microemulsion, whereby any water-soluble biologically-active material in the aqueous phase is released for absorption by the body. The w/o microemulsion is particularly useful for storing proteins and the like for long periods of time at room temperature and above until they are ready for use, at which time the addition of aqueous fluid converts the microemulsion to an o/w emulsion and releases the protein.

US Patent:

56887612, Nov 18, 1997

Filed:

Jun 8, 1995

Appl. No.:

8/406862

Inventors:

Albert J. Owen - West Chester PA
Seang H. Yiv - Wilmington DE
Ani B. Sarkahian - Bryn Mawr PA

Assignee:

LDS Technologies, Inc. - Boothwyn PA

International Classification:

A61K 9107
A61K 3816
A61K 3900

US Classification:

514 2

Abstract:

There is provided a water-in-oil (w/o) micro emulsion which readily converts to an oil-in-water (o/w) emulsion by the addition of aqueous fluid to the w/o microemulsion, whereby an water-soluble biologically-active material in the aqueous phase is released for absorption by the body. The w/o microemulsion contains a preferred high purity short chain monoglyceride surfactant. The w/o microemulsion is particularly useful for storing proteins and the like for ling periods of time at room temperature and above until they are ready for use, at which time the addition of aqueous fluid converts the microemulsion to an o/w emulsion and release the protein.