NIH since Apr 2011
Technical Director of NIH Stem Cell Unit
NIH 2003 - Apr 2010
Scientist in NIH Stem Cell Unit
Psychiatric Genomics 2001 - 2003
Scientist
Lerner Research Institute 1996 - 2001
Postdoctoral Research Fellow
Merck Sharp Dohme 1994 - 1994
Graduate student
Education:
University of York 1992 - 1996
DPhil, Biochemistry
The University of Wolverhampton 1986 - 1990
BSc, Microbiology and Genetics
Friends' School Lisburn 1978 - 1985
Skills:
Stem Cells Cell Culture Differentiation Biochemistry Nih Cell Biology Flow Cytometry Immunocytochemistry Facs Molecular Biology Technology Transfer Lifesciences Immunofluorescence Elisa Western Blotting Neuroscience Cancer Translational Medicine Stem Cell Research Gene Expression Embryonic Stem Cells Genomics Immunology Confocal Microscopy Assay Development Cell Fluorescence Microscopy Neurodegeneration Pharmacology Protein Chemistry Drug Discovery In Vitro Biotechnology Laboratory Life Sciences Laboratory Skills
Pascal Laeng - Washington DC, US Barbara Mallon - Gaithersburg MD, US Lee Pitts - Falls Church VA, US
Assignee:
Psychiatric Genomics, Inc.
International Classification:
C12N005/08 A61K031/19
US Classification:
435/368000, 514/557000
Abstract:
The present invention relates to a method for differentiating a neural stem cell into a neuronal cell such as a neuroblast or neuron in vitro or in vivo. Particularly, the invention provides for a method for neural stem cell differentiation by contacting the neural stem cell with a valproate compound or analog thereof.