Dengue Tetravalent Vaccine Containing A Common 30 Nucleotide Deletion In The 3′-Utr Of Dengue Types 1, 2, 3, And 4 Or Antigenic Chimeric Dengue Viruses 1, 2, 3, And 4
Stephen S. Whitehead - Montgomery Village MD, US Brian R. Murphy - Bethesda MD, US Lewis Markoff - Bethesda MD, US Barry Falgout - Rockville MD, US Joseph Blaney - Frederick MD, US Kathryn Hanley - Las Cruces NM, US
Assignee:
The United States of America as represented by the Department of Health and Human Services - Washington DC
The invention relates to a dengue virus tetravalent vaccine containing a common 30 nucleotide deletion (Δ30) in the 3′-untranslated region of the genome of dengue virus serotypes 1, 2, 3, and 4, or antigenic chimeric dengue viruses of serotypes 1, 2, 3, and 4.
Dengue Tetravalent Vaccine Containing A Common 30 Nucleotide Deletion In The 3'-Utr Of Dengue Types 1,2,3, And 4, Or Antigenic Chimeric Dengue Viruses 1,2,3, And 4
Stephen Whitehead - Montgomery Village MD, US Brian Murphy - Bethesda MD, US Lewis Markoff - Bethesda MD, US Barry Falgout - Rockville MD, US Joseph Blaney - Frederick MD, US Kathryn Hanley - Las Cruces NM, US
International Classification:
A61K 39/12 C12N 15/86
US Classification:
424218100, 435456000
Abstract:
The invention relates to a dengue virus tetravalent vaccine containing a common 30 nucleotide deletion (Δ30) in the 3′-untranslated region of the genome of dengue virus serotypes 1, 2, 3, and 4, or antigenic chimeric dengue viruses of serotypes 1, 2, 3, and 4.
Dengue Tetravalent Vaccine Containing A Common 30 Nucleotide Deletion In The 3'-Utr Of Dengue Types 1, 2, 3, And 4, Or Antigenic Chimeric Dengue Viruses 1, 2, 3, And 4
Stephen S. Whitehead - Bethesda MD, US Brian R. Murphy - Bethesda MD, US Lewis Markoff - Bethesda MD, US Barry Falgout - Rockville MD, US Joseph Blaney - Gettysburg PA, US Kathryn Hanley - Las Cruces NM, US
Assignee:
The Government of the USA, as represented by the Secretary, Department of Health and Human Services - Bethesda MD
The invention relates to a dengue virus tetravalent vaccine containing a common nucleotide deletion (Δ) in the ′-untranslated region of the genome of dengue virus serotypes , and , or antigenic chimeric dengue viruses of serotypes , and
Dengue Tetravalent Vaccine Containing A Common 30 Nucleotide Deletion In The 3'-Utr Of Dengue Types 1,2,3, And 4, Or Antigenic Chimeric Dengue Viruses 1,2,3, And 4
- Bethesda MD, US Brian R. Murphy - Bethesda MD, US Lewis Markoff - Bethesda MD, US Barry Falgout - Rockville MD, US Joseph Blaney - Gettysburg PA, US Kathryn Hanley - Las Cruces NM, US
Assignee:
The United States of America, as represented by the Secretary, Dept. of Health and Human Services - Bethesda MD
International Classification:
C12N 7/00 A61K 39/12
Abstract:
The invention relates to a dengue virus tetravalent vaccine containing a common 30 nucleotide deletion (Δ30) in the 3′-untranslated region of the genome of dengue virus serotypes 1, 2, 3, and 4, or antigenic chimeric dengue viruses of serotypes 1, 2, 3, and 4.
Dengue Tetravalent Vaccine Containing A Common 30 Nucleotide Deletion In The 3'-Utr Of Dengue Types 1, 2, 3, And 4, Or Antigenic Chimeric Dengue Viruses 1, 2, 3, And 4
- Bethesda MD, US Brian R. Murphy - Bethesda MD, US Lewis Markoff - Bethesda MD, US Barry Falgout - Rockville MD, US Joseph Blaney - Gettysburg PA, US Kathryn Hanley - Las Cruces NM, US
Assignee:
The United States of America,as represented by the Secretary, Department of Helath and Human Service - Bethesda MD
International Classification:
C12N 7/00 A61K 39/12 A61K 39/00
Abstract:
The invention relates to a dengue virus tetravalent vaccine containing a common 30 nucleotide deletion (Δ30) in the 3′-untranslated region of the genome of dengue virus serotypes 1, 2, 3, and 4, or antigenic chimeric dengue viruses of serotypes 1, 2, 3, and 4.