Barry B Hudson

US Patent:

20090220484, Sep 3, 2009

Filed:

Mar 17, 2006

Appl. No.:

11/886651

Inventors:

Ann Marie Schmidt - Franklin Lakes NJ, US
Barry Hudson - New York NY, US

International Classification:

A61K 39/395
C07K 16/18
C12N 15/11
C12N 15/00
C12N 5/06
C12N 1/21
C12N 1/19

US Classification:

4241301, 5303871, 536 2353, 4353201, 435326, 4352523, 4352524, 43525411

Abstract:

This invention provides a polypeptide consisting essentially of all or a portion of the cytoplasmic domain of RAGE. This invention further provides a polypeptide consisting essentially of a portion of Diaphanous that binds to the cytoplasmic domain of RAGE. Additionally, this invention provides related nucleic acids, vectors, cells and methods.

US Patent:

20110311448, Dec 22, 2011

Filed:

Oct 31, 2008

Appl. No.:

12/734449

Inventors:

Ann Marie Schmidt - Franklin Lakes NJ, US
Lynne Johnson - New York NY, US
Barry Hudson - New York NY, US
Yared Tekabe - Yonkers NY, US

International Classification:

A61K 49/00
A61P 9/10
A61K 39/395
C07K 16/00
C07K 16/18

US Classification:

424 91, 5303879, 5303913, 5303917, 4241781

Abstract:

This invention discloses an antibody which is raised to a peptide, the sequence of which is: N-R-N-G-K-E-T-K-S-N-Y-R-V-R-V-Y-Q-I-P, N-R-R-G-K-E-V-K-S-N-Y-R-V-R-V-Y-Q-I-P, S-R-N-G-K-E-T-K-S-N-Y-R-V-Q-V-Y-Q-I-P, N-R-R-G-K-E-V-K-S-N-Y-R-V-R-V-Y-Q-I-C, or Ac-N-R-R-G-K-E-V-K-S-N-Y-R-V-R-V-Y-Q-I-C-amide. This antibody can be labeled with an imageable marker or linked to an agent. This antibody can be a monoclonal antibody. The invention also includes a method for determining the location of receptor advanced glycation endproduct (RAGE) in a subject comprising administering the antibody labeled with an imageable marker and detecting the location of the labeled antibody in the subject thereby determining the location of RAGE in the subject. This invention further describes a method for treating a RAGE-related disorder in a subject comprising administering to the subject a therapeutically effective amount of the antibody which binds to the above-described epitope linked to an agent.

US Patent:

48653730, Sep 12, 1989

Filed:

Jun 20, 1988

Appl. No.:

7/208755

Inventors:

Barry C. Hudson - Phillipsburg NJ

International Classification:

E01H 502

US Classification:

294 545

Abstract:

A manually-operated snow shovel has wheels in front of and behind the blade, to position the blade at an angle between 30 degrees and 35 degrees with the horizontal. An angularly bent handle positions grips at about waist height, to permit a person to roll the shovel on the surface being cleaned.