Carl B Heilman

US Patent:

20120296256, Nov 22, 2012

Filed:

Aug 8, 2012

Appl. No.:

13/569212

Inventors:

Carl Heilman - Wayland MA, US
Adel M. Malek - Lexington MA, US

Assignee:

TUFTS MEDICAL CENTER - Boston MA

International Classification:

A61M 1/00

US Classification:

604 8

Abstract:

An implantable shunt device for draining cerebrospinal fluid from a patient's subarachnoid space. The device includes a shunt having opposed first and second ends. A one-way valve is located at the first end of the shunt. A helical tip is disposed at the second end. The helical tip is constructed to penetrate a sinus wall of the patient. Upon implantation, a hollow passageway extends between the helical tip and one-way valve such that fluid can be drained through the helical tip and out through the valve. The endovascular cerebrospinal fluid shunt of the present invention can be placed into a patient percutaneously via a catheter inserted into the venous system of the body through a needle hole, without the need for open surgery and the skin incisions required with current shunt devices. The device also allows for more physiologic drainage of cerebrospinal fluid since the device is shunting cerebrospinal fluid into the same cerebral venous system that occurs naturally in normal people.

US Patent:

20100191168, Jul 29, 2010

Filed:

Jan 29, 2009

Appl. No.:

12/362152

Inventors:

Carl HEILMAN - Wayland MA, US

Assignee:

TRUSTEES OF TUFTS COLLEGE - Medford MA

International Classification:

A61M 1/00

US Classification:

604 9

Abstract:

An implantable shunt device for draining cerebrospinal fluid from a patient's subarachnoid space. The device includes a shunt having opposed first and second ends. A one-way valve is located at the first end of the shunt. A helical tip is disposed at the second end. The helical tip is constructed to penetrate a sinus wall of the patient. Upon implantation, a hollow passageway extends between the helical tip and one-way valve such that fluid can be drained through the helical tip and out through the valve. The endovascular cerebrospinal fluid shunt of the present invention can be placed into a patient percutaneously via a catheter inserted into the venous system of the body through a needle hole, without the need for open surgery and the skin incisions required with current shunt devices. The device also allows for more physiologic drainage of cerebrospinal fluid since the device is shunting cerebrospinal fluid into the same cerebral venous system that occurs naturally in normal people.

US Patent:

20210268252, Sep 2, 2021

Filed:

May 11, 2021

Appl. No.:

17/317027

Inventors:

- Auburndale MA, US
Carl B. Heilman - Wayland MA, US
David A. Rezac - Westborough MA, US
Jack B. Sattell - Boston MA, US
Alexander Bonin - Franklin MA, US

Assignee:

CEREVASC, INC. - Auburndale MA

International Classification:

A61M 39/02
A61M 25/00

Abstract:

Endovascular drug delivery systems and methods are disclosed herein for delivering a therapeutic agent to the intracranial subarachnoid space of a patient, and/or deploying an endovascular drug delivery device distal portion in the intracranial subarachnoid space and a portion of the drug delivery device body in a dural venous sinus such that a therapeutic agent is delivered from the deployed drug delivery device into the intracranial subarachnoid space.

US Patent:

20200406018, Dec 31, 2020

Filed:

Mar 8, 2019

Appl. No.:

16/976057

Inventors:

- Auburndale MA, US
Carl B. Heilman - Wayland MA, US
David A. Rezac - Westborough MA, US
Jack B. Sattell - Boston MA, US
Alexander Bonin - Franklin MA, US

Assignee:

CEREVASC, INC. - Auburndale MA

International Classification:

A61M 39/02

Abstract:

Endovascular drug delivery systems and methods are disclosed herein for delivering a therapeutic agent to the intracranial subarachnoid space of a patient, and/or deploying an endovascular drug delivery device distal portion in the intracranial subarachnoid space and a portion of the drug delivery device body in a dural venous sinus such that a therapeutic agent is delivered from the deployed drug delivery device into the intracranial subarachnoid space.

US Patent:

20200368506, Nov 26, 2020

Filed:

Aug 5, 2020

Appl. No.:

16/986245

Inventors:

- Auburndale MA, US
Carl Heilman - Wayland MA, US
David A. Rezac - Westborough MA, US
Jack B. Sattell - Boston MA, US
Anthony Maiorano - Jamaica Plain MA, US

Assignee:

CEREVASC, INC. - Auburndale MA

International Classification:

A61M 27/00
A61M 25/04

Abstract:

Systems and methods for implanting an endovascular shunt in a patient is disclosed. The system having an expandable anchor configured for being deployed in a dural venous sinus of a patient at a location distal to a curved portion of a wall of an inferior petrosal sinus (IPS) of the patient; an elongate guide member coupled to, and extending proximally from, the anchor; a shunt delivery catheter having a first lumen configured to receive the guide member, and a second lumen extending between respective proximal and distal openings in the shunt delivery catheter, the shunt delivery catheter further having a penetrating element coupled to a distal end of the catheter; and the system further having a guard at least partially disposed over, and movable relative to, the penetrating element.

US Patent:

20200069927, Mar 5, 2020

Filed:

Mar 2, 2018

Appl. No.:

16/489624

Inventors:

- Auburndale MA, US
Carl Heilman - Wayland MA, US
David A. Rezac - Westborough MA, US
Jack B. Sattell - Boston MA, US
Alexander Bonin - Bellingham MA, US

International Classification:

A61M 27/00
A61M 25/00

Abstract:

In some aspects, catheter devices can include: a reinforcing member having a proximal and distal ends, the reinforcing member comprising: discrete longitudinally arranged structural regions between the proximal and distal ends comprising: a first, proximal, structural region defining a first series of wall perforations that generate structural properties within the first structural region, the first series of wall perforations setting a first stiffness of the first structural region; and a second structural region, disposed distally relative to the first structural region, defining a second series of wall perforations that generate structural properties within the second structural region, the second series of wall perforations setting a second stiffness of the second structural region, which is less than the first stiffness, wherein the second series of wall perforations differs from the first series of wall perforations by at least one of: cut balance, cut frequency, or pitch.

US Patent:

20190307403, Oct 10, 2019

Filed:

Mar 20, 2019

Appl. No.:

16/359705

Inventors:

- Boston MA, US
Carl Heilman - Wayland MA, US

International Classification:

A61B 5/00
A61B 5/1455
A61N 1/05
A61N 1/365
A61N 5/06
A61N 7/00
A61B 5/145
A61B 5/0478
A61B 5/03
A61B 5/11
A61B 5/01

Abstract:

An implant sized and shaped to be endovascularly delivered to the middle meningeal artery includes a carrier that carries a payload between first and second ends thereof. An anchor mechanism associated with the implant transitions into a swollen state in response to exposure to bodily fluids. In the swollen state, said anchor mechanism anchors the implant to the middle meningeal artery. Before or during the transition, the anchor mechanism permits endovascular delivery of the implant to the middle meningeal artery.

US Patent:

20180256866, Sep 13, 2018

Filed:

May 16, 2018

Appl. No.:

15/981497

Inventors:

- Auburndale MA, US
Carl Heilman - Wayland MA, US
David A. Rezac - Westborough MA, US
Jack B. Sattell - Boston MA, US
Anthony Maiorano - Jamaica Plain MA, US

Assignee:

CereVasc, LLC - Auburndale MA

International Classification:

A61M 27/00
A61M 25/09
A61M 25/01
A61M 25/04
A61M 25/06

Abstract:

Systems and methods for implanting an endovascular shunt in a patient is disclosed. The system having an expandable anchor configured for being deployed in a dural venous sinus of a patient at a location distal to a curved portion of a wall of an inferior petrosal sinus (IPS) of the patient; an elongate guide member coupled to, and extending proximally from, the anchor; a shunt delivery catheter having a first lumen configured to receive the guide member, and a second lumen extending between respective proximal and distal openings in the shunt delivery catheter, the shunt delivery catheter further having a penetrating element coupled to a distal end of the catheter; and the system further having a guard at least partially disposed over, and movable relative to, the penetrating element.

Author:

Carl Heilman

ISBN #:

0760325804

Author:

Carl Heilman

ISBN #:

0847827909

Author:

Carl Heilman

ISBN #:

0935272747

Author:

Carl E. Heilman

ISBN #:

0760329559

Author:

Carl E. Heilman

ISBN #:

0847821692

Author:

Carl E. Heilman

ISBN #:

0847821706

Author:

Carl E. Heilman

ISBN #:

0896586634

Author:

Carl E. Heilman

ISBN #:

0961316128