Cynthia A Guzzo

US Patent:

7064108, Jun 20, 2006

Filed:

Feb 4, 2003

Appl. No.:

10/504262

Inventors:

Cynthia A. Guzzo - Rydal PA, US
Coleen M. Clineschmidt - Perkiomenville PA, US
George Schorn - North Wales PA, US
James M. Reynolds - Harleysville PA, US

Assignee:

Merck & Co., Inc. - Rahway NJ
McNeil-PPC, Inc. - Fort Washington PA

International Classification:

A01N 43/04
A61K 31/70

US Classification:

514 27, 514 30

Abstract:

A topical gel composition comprising between about 0. 005 and 1. 0% ivermectin, between about 30 and 40% of a pharmaceutically acceptable alcohol, between about 30 and 40% of a pharmaceutically acceptable glycol, and a pharmaceutically acceptable carrier, useful for treating Pediculosis capitis infestation in a human patient.

US Patent:

62620312, Jul 17, 2001

Filed:

Mar 10, 2000

Appl. No.:

9/523335

Inventors:

Stephanie Larouche - Princeton Junction NJ
Cynthia Guzzo - Rydal PA
Alfred J. Saah - Blue Bell PA
Kenneth Brown - Philadelphia PA

Assignee:

Merck & Co., Inc. - Rahway NJ

International Classification:

A61K 3170

US Classification:

514 30

Abstract:

A method for treating Pediculosis capitis infestation in a human patient which comprises orally administering to the human a total amount of ivermectin of between about 400 ug/kg and about 1200 ug/kg over a period of time of about one week, wherein equal portions of the total amount are administered according to an administration sequence selected from the group consisting of c) a first day and a second day, and d) a first day, a second day and a third day, during the one week time period. The invention is also a method for treating Pediculosis capitis infestation in a human patient which comprises orally administering to the human a total amount of ivermectin of between about 6 mg and 135 mg over a period of time of about one week, wherein equal portions of the total amount are administered according to an administration sequence selected from the group consisting of e) a first day and a second day, and f) a first day, a second day and a third day, during the one week time period.