Daniel Bowers (born 1955 in Stoke-on-Trent, England) was a footballer who played in The Football League for Crewe Alexandra, Shrewsbury Town and Stoke City. ...
Parminder Singh - Union City CA, US Robert Wade Worsham - Cupertino CA, US Joseph C. Trautman - Sunnyvale CA, US Danir Bayramov - Sunnyvale CA, US Danny Lee Bowers - Lake Odessa MI, US Andy Klemm - Grand Rapids MI, US Steven Richard Klemm - Grand Rapids MI, US Guohua Chen - Sunnyvale CA, US
International Classification:
A61M 37/00 B29C 43/14
US Classification:
604173, 264 401, 264 87, 264 86
Abstract:
In an aspect of the invention, an array of microprotrusions is formed by providing a mold with cavities corresponding to the negative of the microprotrusions, casting atop the mold a first solution comprising a biocompatible material and a solvent, removing the solvent, casting a second solution atop the first cast solution, removing the solvent from the second solution, and demolding the resulting array from the mold. The first solution preferably contains an active ingredient.
Esi Ghartey-Tagoe - Foster City CA, US Janet Wendorf - Redwood City CA, US Steve Williams - El Granada CA, US Parminder Singh - Union City CA, US Robert Wade Worsham - Cupertino CA, US Joseph C. Trautman - Sunnyvale CA, US Danir Bayramov - Sunnyvale CA, US Danny Lee Bowers - Lake Odessa MI, US Andy Klemm - Grand Rapids MI, US Steven Richard Klemm - Grand Rapids MI, US Guohua Chen - Sunnyvale CA, US
A microprojection array is provided, comprising an approximately planar base and a plurality of microprojections, wherein the array comprises a vaccine and a polymeric material. The array may have multiple layers. The vaccine may be placed in only one layer. In another embodiment of the invention, a method of preventing a disease is provided, comprising insertion into the skin of a patient an array of microprojections comprising a layer which comprises a vaccine for that disease and a polymer.
Solvent-Cast Microprotrusion Arrays Containing Active Ingredient
Robert Wade Worsham - Cupertino CA, US Joseph C. Trautman - Sunnyvale CA, US Danir Bayramov - Sunnyvale CA, US Danny Lee Bowers - Lake Odessa MI, US Andy Klemm - Grand Rapids MI, US Steven Richard Klemm - Grand Rapids MI, US Guohua Chen - Sunnyvale CA, US
International Classification:
A61M 37/00
US Classification:
264102
Abstract:
In an aspect of the invention, an array of microprotrusions is formed by providing a mold with cavities corresponding to the negative of the microprotrusions, casting atop the mold a first solution comprising a biocompatible material and a solvent, removing the solvent, casting a second solution atop the first cast solution, removing the solvent from the second solution, and demolding the resulting array from the mold. The first solution preferably contains an active ingredient.
Joseph C. Trautman - Sunnyvale CA, US Robert Wade Worsham - Cupertino CA, US Danir F. Bayramov - Sunnyvale CA, US Danny Lee Bowers - Lake Odessa MI, US Steven Richard Klemm - Grand Rapids MI, US Parminder Singh - Union City CA, US
International Classification:
A61M 5/158
US Classification:
604272
Abstract:
A microneedle applicator is provided which has two roughly concentric portions which may be, for example, a solid disk and an annulus surrounding it. On the skin-facing side of the inner portion of the applicator a microneedle array is located. The outer portion of the applicator is placed against the skin, contacting it at a zone. The microneedle array is then pressed towards the skin.
Solvent-Cast Microprotrusion Arrays Containing Active Ingredient
- Menlo Park CA, US Robert Wade WORSHAM - Sutter Creek CA, US Joseph C. TRAUTMAN - Sunnyvale CA, US Danir BAYRAMOV - Irvine CA, US Danny Lee BOWERS - Lake Odessa MI, US Andrew Richard KLEMM - Ada MI, US Steven Richard KLEMM - Grand Rapids MI, US Guohua CHEN - Sunnyvale CA, US
International Classification:
A61M 37/00 A61K 38/29 A61K 38/38 A61K 9/00
Abstract:
In an aspect of the invention, an array of microprotrusions is formed by providing a mold with cavities corresponding to the negative of the microprotrusions, casting atop the mold a first solution comprising a biocompatible material and a solvent, removing the solvent, casting a second solution atop the first cast solution, removing the solvent from the second solution, and demolding the resulting array from the mold. The first solution preferably contains an active ingredient.
Solvent-Cast Microprotrusion Arrays Containing Active Ingredient
- Menlo Park CA, US Robert Wade Worsham - Cupertino CA, US Joseph C. Trautman - Sunnyvale CA, US Danir Bayramov - Irvine CA, US Danny Lee Bowers - Lake Odessa MI, US Andrew Richard Klemm - Ada MI, US Steven Richard Klemm - Grand Rapids MI, US Guohua Chen - Sunnyvale CA, US
International Classification:
A61M 37/00 A61K 38/29 A61K 38/38 A61K 9/00
Abstract:
In an aspect of the invention, an array of microprotrusions is formed by providing a mold with cavities corresponding to the negative of the microprotrusions, casting atop the mold a first solution comprising a biocompatible material and a solvent, removing the solvent, casting a second solution atop the first cast solution, removing the solvent from the second solution, and demolding the resulting array from the mold. The first solution preferably contains an active ingredient.
- Menlo Park CA, US Janet Wendorf - Redwood City CA, US Steve Williams - El Granada CA, US Parminder Singh - Union City CA, US Robert Wade Worsham - Cupertino CA, US Joseph C. Trautman - Sunnyvale CA, US Danir Bayramov - Irvine CA, US Danny Lee Bowers - Lake Odessa MI, US Andrew Richard Klemm - Ada MI, US Steven Richard Klemm - Grand Rapids MI, US Guohua Chen - Sunnyvale CA, US
International Classification:
A61K 39/07 A61K 9/00
US Classification:
4242461
Abstract:
A microprojection array is provided, comprising an approximately planar base and a plurality of microprojections, wherein the array comprises a vaccine and a polymeric material. The array may have multiple layers. The vaccine may be placed in only one layer. In another embodiment of the invention, a method of preventing a disease is provided, comprising insertion into the skin of a patient an array of microprojections comprising a layer which comprises a vaccine for that disease and a polymer.
Dorsey Wilcox, Patricia Haughenberry, Karen Johnson, Kathleen Moreland, Leslie Egelston, Mike Woods, Stephen Pack, Marva Prinds, Becky Park, Marilyn Thomas, Jack Bliven