Darryl M See

US Patent:

6884420, Apr 26, 2005

Filed:

May 19, 2003

Appl. No.:

10/440110

Inventors:

Darryl See - Laguna Niguel CA, US

Assignee:

Cross Bay, LLC - Las Vegas NV

International Classification:

A61K035/84
A61K035/78

US Classification:

42419515, 424725

Abstract:

A composition for reducing blood sugar in humans in need thereof, contains , alpha lipoic acid, transfer factor, polymannose, fenugreek, coenzyme Q-10, selenium, zinc, vitamin C, vitamin E, chromium and vanadium.

US Patent:

20010024651, Sep 27, 2001

Filed:

Mar 26, 2001

Appl. No.:

09/817649

Inventors:

Jackie See - Reno NV, US
Darryl See - Laguna Niguel CA, US

International Classification:

A61K009/127
A61K039/21

US Classification:

424/187100

Abstract:

A method is provided for inducing a systemic immune response to an antigen selected from inactivated HIV I and HIV II antigens in a mammal. The method comprises orally administering lyophilized multilaminar liposomes containing the antigen. The liposomes have a size of from 20 nm to 20 microns. The antigen-containing liposomes are absorbed in the Peyer's patches of the gut. Sufficient antigen-containing liposomes are taken up by macrophages in the Peyer's patches to induce a systemic immune response to the antigen.

US Patent:

20020136762, Sep 26, 2002

Filed:

Jan 25, 2002

Appl. No.:

10/057484

Inventors:

Jackie See - Fullerton CA, US
Darryl See - Laguna Niguel CA, US

International Classification:

A61K039/00
A61K009/127

US Classification:

424/450000, 424/184100

Abstract:

A method is provided for inducing a systemic immune response to an antigen. The method comprises providing a liposomal preparation comprising lyophilized liposomes containing at least one antigen. The liposomes have at least two sizes, before lyophilization, selected from small liposomes having a size, before lyophilization, of from about 20 nm to about 1 micron, medium liposomes having a size, before lyophilization, of from about 1 micron to about 3 microns, and large liposomes having a size, before lyophilization, of from about 3 microns to about 20 microns. An effective amount of the liposomal preparation is administered to a mammal, whereby sufficient antigen containing liposomes are absorbed in the Peyer's patches of the gut of the mammal and are taken up by macrophages in the Peyer's patches to stimulate a systemic immune response.

US Patent:

20020142030, Oct 3, 2002

Filed:

Jan 25, 2002

Appl. No.:

10/056972

Inventors:

Jackie See - Reno NV, US
Darryl See - Laguna Niguel CA, US

Assignee:

Oral Vaccine Technologies, Inc.

International Classification:

A61K039/145
A61K009/127

US Classification:

424/450000, 424/206100

Abstract:

A method is provided for inducing a systemic immune response to an antigen selected from inactivated HIV I and HIV II antigens in a mammal. The method comprises orally administering lyophilized multilaminar liposomes containing the antigen. The liposomes have a size of from 20 nm to 20 microns. The antigen-containing liposomes are absorbed in the Peyer's patches of the gut. Sufficient antigen-containing liposomes are taken up by macrophages in the Peyer's patches to induce a systemic immune response to the antigen.

US Patent:

20040258746, Dec 23, 2004

Filed:

Apr 8, 2004

Appl. No.:

10/821691

Inventors:

Jackie See - Fullerton CA, US
Darryl See - Laguna Niguel CA, US

Assignee:

Oral Vaccine Technologies, Inc.

International Classification:

A61K039/00
A61K009/127

US Classification:

424/450000, 424/184100

Abstract:

A method is provided for inducing a systemic immune response to an antigen. The method comprises providing a liposomal preparation comprising lyophilized liposomes containing at least one antigen. The liposomes have at least two sizes, before lyophilization, selected from small liposomes having a size, before lyophilization, of from about 20 nm to about 1 micron, medium liposomes having a size, before lyophilization, of from about 1 micron to about 3 microns, and large liposomes having a size, before lyophilization, of from about 3 microns to about 20 microns. An effective amount of the liposomal preparation is administered to a mammal, whereby sufficient antigen containing liposomes are absorbed in the Peyer's patches of the gut of the mammal and are taken up by macrophages in the Peyer's patches to stimulate a systemic immune response.

US Patent:

60155760, Jan 18, 2000

Filed:

Aug 29, 1997

Appl. No.:

8/920374

Inventors:

Jackie R. See - Reno NV
Darryl M. See - Laguna Niguel CA

Assignee:

Bio-Sphere Technology, Inc. - Reno NV

International Classification:

A61K 9127
A61K 9133

US Classification:

424450

Abstract:

A method is provided for inducing a systemic immune response to an antigen in a mammal. The method comprises orally administering lyophilized multilamellar liposomes containing the antigen. The liposomes have a size of from 20 nm to 20 microns. The antigen-containing liposomes are absorbed in the Peyer's patches of the gut. Sufficient antigen-containing liposomes are taken up by macrophages in the Peyer's patches to induce a systemic immune response to the antigen.

US Patent:

62071858, Mar 27, 2001

Filed:

Oct 10, 1997

Appl. No.:

8/948568

Inventors:

Jackie R. See - Reno NV
Darryl M. See - Laguna Niguel CA

Assignee:

Bio-Sphere Technology - Reno NV

International Classification:

A61K9/127;9/133

US Classification:

424450

Abstract:

A method is provided for inducing a systemic immune response to an antigen selected from inactivated HIV I and HIV II antigens in a mammal. The method comprises orally administering lyophilized multilaminar liposomes containing the antigen. The liposomes have a size of from 20 nm to 20 microns. The antigen-containing liposomes are absorbed in the Peyer's patches of the gut. Sufficient antigen-containing liposomes are taken up by macrophages in the Peyer's patches to induce a systemic immune response to the antigen.

US Patent:

61174491, Sep 12, 2000

Filed:

Jan 14, 1998

Appl. No.:

9/007297

Inventors:

Jackie R. See - Reno NV
Darryl M. See - Laguna Niguel CA

Assignee:

Bio-Sphere Technology, Inc. - Reno NV

International Classification:

A61K 9127
A61K 3929

US Classification:

424450

Abstract:

A method is provided for inducing a systemic immune response to an antigen selected from hepatitis B and hepatitis C antigens in a mammal. The method comprises orally administering lyophilized multilamellar liposomes containing the antigen. The liposomes have a size of from 20 nm to 20 microns. The antigen-containing liposomes are absorbed in the Peyer's patches of the gut. Sufficient antigen-containing liposomes are taken up by macrophages in the Peyer's patches to induce a systemic immune response to the antigen.