Denis Evseenko

US Patent:

20100129910, May 27, 2010

Filed:

Jul 2, 2009

Appl. No.:

12/459582

Inventors:

Denis Evseenko - Pasadena CA, US
Gay Crooks - Sherman Oaks CA, US

International Classification:

C12N 5/02
C12N 5/00

US Classification:

435383, 435404, 435325

Abstract:

The present invention relates to compositions and methods for the generation of embryoid bodies from embryonic stem cells, and for aggregation of ES cells for establishing ES cell colonies from small numbers of cells. Compositions of the invention, in certain embodiments, comprise embryonic stem cells, an extracellular matrix molecule, and a molecule capable of cross linking. The present invention also relates to methods for embryoid body formation using a composition of the invention and to cells and tissues isolated or derived from an embryoid body generated with a composition or method of the invention.

US Patent:

20230099151, Mar 30, 2023

Filed:

Aug 17, 2022

Appl. No.:

17/820522

Inventors:

- Los Angeles CA, US
Denis Evseenko - Tarzana CA, US

International Classification:

C07D 417/12
A61P 19/02
A61K 9/00
A61K 9/16
A61K 31/4439
A61K 31/444
A61K 45/06
C07D 401/12

Abstract:

The disclosure provides compounds and method useful for modulating gp130 biological activity. The disclosure also provides methods and compositions for treating disease and disorders associated with gp130 activity, particularly those associated with inflammation.

US Patent:

20200377494, Dec 3, 2020

Filed:

Jun 10, 2020

Appl. No.:

16/898236

Inventors:

- Los Angeles CA, US
Denis Evseenko - Tarzana CA, US

International Classification:

C07D 417/12
A61K 9/16
A61K 9/00
A61K 31/444
A61K 45/06
C07D 401/12
A61K 31/4439
A61P 19/02

Abstract:

The disclosure provides compounds and method useful for modulating gp130 biological activity. The disclosure also provides methods and compositions for treating disease and disorders associated with gp130 activity, particularly those associated with inflammation.