Yuri Svirkin - Winchester MA, US Ramine Parsa - Waltham MA, US Dmitry Zingerman - North Quincy MA, US
International Classification:
A61K 38/16
US Classification:
514008000
Abstract:
The invention provides compositions for the treatment of disorders characterized by dryness including dry eye and dry mouth. The compositions commonly comprise a conjugate of hyaluronic acid and polylysine. These conjugates are attached to affected body tissues or surfaces using transglutaminase, and preferably endogenous transglutaminase.