Eamon J Comer

US Patent:

20070212267, Sep 13, 2007

Filed:

Feb 28, 2007

Appl. No.:

11/711831

Inventors:

Michael Organ - Burlington, CA
Eamon Comer - Brookline MA, US

Assignee:

Total Synthesis Ltd. - Burlington

International Classification:

B01J 19/00

US Classification:

422130000

Abstract:

A reactor apparatus includes at least one reaction capillary having a lumen for receiving a reactant to undergo a reaction, and a magnetron for irradiating reactant contained in at least a portion of the capillary with microwaves. A method of micro-reacting a reactant includes providing a capillary, and irradiating the reactant in the capillary with microwaves to facilitate a chemical reaction in the capillary by which the reactant is converted into a desired product.

US Patent:

20150216855, Aug 6, 2015

Filed:

Aug 19, 2013

Appl. No.:

14/421778

Inventors:

- Cambridge MA, US
Jose R. Perez - Salem CT, US
Michelle Palmer - Harvard MA, US
Adam Skepner - Woburn MA, US
Eamon Comer - Watertown MA, US

International Classification:

A61K 31/4725
A61K 45/06
C12Q 1/68
A61K 31/422
A61K 31/381
A61K 31/4025
A61K 31/35

Abstract:

The present invention relates to compounds that are useful for modulating hepatic cholesterol metabolism in an animal. The invention includes methods of making and using the compounds of the invention. The invention further provides methods of treating, preventing and/or alleviating a cholesterol related disorder, a cardiovascular disease and/or liver disease in an animal, such as a human, comprising administering compounds of the invention, or pharmaceutically acceptable salts or solvates thereof, to the animal.