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Edith C Wolff

age ~94

from Bethesda, MD

Edith Wolff Phones & Addresses

  • 7917 Deepwell Dr, Bethesda, MD 20817 • 3013651405

Work

  • Company:
    National institutes of health
  • Address:
    9000 Rckvlle Pike Bldg 31, Bethesda, MD 20892
  • Phones:
    3014964000
  • Position:
    Biochemist ret
  • Industries:
    Administration of Public Health Programs

Ranks

  • Licence:
    Washington - Active
  • Date:
    1989

Us Patents

  • Methods Of Inhibiting Formation Of Vascular Channels And Methods Of Inhibiting Proliferation

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  • US Patent:
    7141589, Nov 28, 2006
  • Filed:
    Aug 23, 2002
  • Appl. No.:
    10/486671
  • Inventors:
    Myung Hee Park - Potomac MD, US
    Paul M Clement - Bethesda MD, US
    Edith C. Wolff - Bethesda MD, US
    Hynda K Kleinman - Kensington MD, US
    Bernadette M Cracchiolo - Edgewater NJ, US
  • Assignee:
    The United States of America as represented by the Department of Health and Human Services - Washington DC
    University of Medicine and Dentistry of New Jersey - New Brunswick NJ
  • International Classification:
    A61K 31/44
    A61K 38/00
  • US Classification:
    514345, 514 2
  • Abstract:
    A method of inhibiting formation of vascular channels in tissues and a method of inhibiting proliferation of a cell of a non-vascularized intraepithelial neoplasia, both of which methods comprise administering to the tissues or the cell a compound.
  • Methods Of Diagnosing And Treating Hyperproliferative Disorders

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  • US Patent:
    20090253777, Oct 8, 2009
  • Filed:
    Sep 13, 2003
  • Appl. No.:
    10/527453
  • Inventors:
    Myung-Hee Park - Potomac MD, US
    Edith C. Wolff - Bethesda MD, US
    Bernadette M. Cracciolo - Edgewater NJ, US
    Anthony Popowicz - Farmingville NY, US
    Paul M.J. Clement - Heverlee, BE
  • International Classification:
    A61K 31/7088
    C07K 16/18
    G01N 33/574
    G01N 33/566
    C12N 5/06
  • US Classification:
    514 44 R, 5303879, 435 723, 436501, 435375
  • Abstract:
    The invention relates to compositions and methods for diagnosing and treating hyperproliferative disorders using ligands which specifically recognize the hypusine and/or folate binding region of mature eukaryotic translation initiation factor 5A (hypusine-containing eIF-5A). The invention further relates to methods of identifying molecules which displace immunoreagents binding to mature eIF-5A. Such agents are useful for treating hyperproliferative disorders.
  • Method Of Preventing Survival Of Retrovirally Cells And Of Inhibiting Formation Of Infectious Retroviruses

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  • US Patent:
    20120095058, Apr 19, 2012
  • Filed:
    Dec 1, 2004
  • Appl. No.:
    10/581658
  • Inventors:
    Paul Palumbo - Westfield NJ, US
    Myung-Hee Park - Potomac MD, US
    Edith Wolff - Bethesda MD, US
    Axel-Rainer Hanauske - Frankfurt, DE
    Michael B. Mathews - Montclair NJ, US
    Deepti Saxena - South Orange NJ, US
    Mainul Hoque - Newark NJ, US
  • International Classification:
    A61K 31/4418
    A61K 31/4439
    A61K 31/4412
    A61P 31/18
    A61P 31/14
    C12N 5/071
    A61K 31/426
    A61P 31/12
  • US Classification:
    514342, 514345, 514365, 435375, 514348
  • Abstract:
    The present invention discloses compounds and pharmaceutical compositions which are highly effective at inhibiting the accumulation of spliced and unspliced viral transcripts and their utilization for viral protein synthesis at cellular ribosomes, and at inhibiting the formation of the hypusine residue in cellular eIF-5A precursor proteins, the cellular cofactors that render spliced and unspliced viral transcripts translatable at the ribosomes of infectled cells. The invention further relates to methods of using such compounds and pharmaceutical compositions therefrom for inhibiting or preventing viral protein synthesis. Such inhibition cause a dose-dependent release from the virally induced arrest of the otherwise genetically preprogrammed apoptosis of virally infected cells, and in consequence, triggers their apoptotic ablation and the eradication of the chronic infection-mediating provirus integrated into their genome.
  • Compositions And Methods For Inhibiting Deoxyhypusine Synthase And The Growth Of Cells

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  • US Patent:
    53448464, Sep 6, 1994
  • Filed:
    Dec 30, 1992
  • Appl. No.:
    7/998231
  • Inventors:
    Judit Jakus - Silver Spring MD
    Myung H. Park - Potomac MD
    Edith C. Wolff - Bethesda MD
    John E. Folk - Derwood MD
  • Assignee:
    The United States of America as represented by the Department of Health
    and Human Services - Washington DC
  • International Classification:
    C07C27904
    A61K 31155
  • US Classification:
    514634
  • Abstract:
    Compositions and methods for the treatment of mammalian cells to inhibit cell growth, especially for inhibiting the proliferative cell growth associated with malignant and non-malignant disease, are provided. More particularly, a deoxyhypusine synthase inhibitor, typically, a mono- or bisguanyl diamine or polyamine, is administered to the cells. Also provided by this invention are diagnostic methods and kits for screening the cells of a patient to determine the effect of the deoxyhypusine synthase inhibitor on proliferation of the cells.
  • Methods Of Diagnosing And Treating Hyperproliferative Disorders

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  • US Patent:
    20180237517, Aug 23, 2018
  • Filed:
    Jan 2, 2014
  • Appl. No.:
    14/146387
  • Inventors:
    Myung-Hee Park - Potomac MD, US
    Edith C. Wolff - Bethesda MD, US
    Bernadette M. Cracchiolo - Edgewater NJ, US
    Anthony Popowicz - Farmingville NY, US
    Paul M. Clement - Heverlee, BE
  • Assignee:
    RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY - New Brunswick NJ
  • International Classification:
    C07K 16/28
    C07K 16/30
    G01N 33/68
    G01N 33/574
  • Abstract:
    The invention relates to compositions and methods for diagnosing and treating hyperproliferative disorders using ligands which specifically recognize the hypusine and/or folate binding region of mature eukaryotic translation initiation factor 5A (hypusine-containing eIF-5A). The invention further relates to methods of identifying molecules which displace immunoreagents binding to mature eIF-5A. Such agents are useful for treating hyperproliferative disorders.

Lawyers & Attorneys

Edith Wolff Photo 1

Edith Gaylord Clark Wolff - Lawyer

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Licenses:
Washington - Active 1989

Resumes

Edith Wolff Photo 2

Edith Wolff

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Edith Wolff Photo 3

Edith Wolff

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Name / Title
Company / Classification
Phones & Addresses
Edith Wolff
Biochemist Ret
National Institutes of Health
Administration of Public Health Programs
9000 Rckvlle Pike Bldg 31, Bethesda, MD 20892

Youtube

Rikard Wolff speaking

The swedish singer Rikard Wolff (also the swedish voice of Scar in Dis...

  • Category:
    Music
  • Uploaded:
    09 Aug, 2006
  • Duration:
    1m 12s

[House/Electro]Q... Wolff - Pou pou pidou - ...

Quentin Wolff feat edith piaf, koxie, marlyn monroe - pou piou pidou A...

  • Category:
    Music
  • Uploaded:
    01 May, 2011
  • Duration:
    2m 10s

Roger Wolfe Kahn Orchestra - A Shine On Your ...

Roger Wolfe Kahn (Oct.19,1907 - July 12,1962) was an American jazz and...

  • Category:
    Music
  • Uploaded:
    05 Nov, 2009
  • Duration:
    3m 14s

Roger Wolfe Kahn and his Hotel Biltmore Orche...

Roger Wolfe Kahn (Oct.19,1907 - July 12,1962) was an American jazz and...

  • Category:
    Music
  • Uploaded:
    27 Feb, 2011
  • Duration:
    3m 2s

Ich werde jede Nacht von Ihnen trumen

Eugen Wolff mit seinem Tanz-Orchester und Gesang: Ralph M. Siegel Parl...

  • Category:
    Music
  • Uploaded:
    18 Feb, 2008
  • Duration:
    2m 46s

Roger Wolfe Kahn's Orch. - Hot Hot Hottentot,...

Roger WOLFE KAHN (1907 - 1962) was an American jazz and popular musici...

  • Category:
    Music
  • Uploaded:
    17 Dec, 2007
  • Duration:
    2m 57s

Edith Waits for Tom - Chocolate Jesus

This video is dedicated to Tom Waits. Chocolate Jesus is my favorite s...

  • Category:
    Music
  • Uploaded:
    24 Aug, 2008
  • Duration:
    5m 28s

Legacy Award - Donor - Alan and Edith Wolff

  • Duration:
    2m 43s

Flickr

Facebook

Edith Wolff Photo 6

Edith Wolff New York NY

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Edith Wolff (New York, NY)
Edith Wolff Photo 7

Edith Wolff

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Friends:
Susan Collier Miller, Melissa Cook, Carly Tram Tran, Catherine Warren
Edith Wolff Photo 8

Edith Wolff Trent / Prin...

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Friends:
Ray Velasquez, Kristy Wolff
Edith Wolff (Trenton / Princeton, NJ)
Edith Wolff Photo 9

Buscar Nombres Edith Wolff

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Googleplus

Edith Wolff Photo 10

Edith Wolff


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