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Edward H Wasmuth

age ~88

from Telford, PA

Also known as:
  • Ed H Wasmuth

Edward Wasmuth Phones & Addresses

  • Telford, PA
  • New Brunswick, NJ

Us Patents

  • Hepatitis B Surface Antigen

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  • US Patent:
    40887480, May 9, 1978
  • Filed:
    May 4, 1977
  • Appl. No.:
    5/793662
  • Inventors:
    William J. McAleer - Ambler PA
    Edward H. Wasmuth - Telford PA
  • Assignee:
    Merck & Co., Inc. - Rahway NJ
  • International Classification:
    A61K 3912
    C12K 700
  • US Classification:
    424 89
  • Abstract:
    Biological fluid containing hepatitis B surface antigen is concentrated using ammonium sulfate, and subjected to an isopycnic banding followed by rate zonal banding.
  • Isolation Of Hb.sub.s Ag

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  • US Patent:
    41817133, Jan 1, 1980
  • Filed:
    Oct 30, 1978
  • Appl. No.:
    5/955863
  • Inventors:
    William J. McAleer - Ambler PA
    Edward H. Wasmuth - Telford PA
  • Assignee:
    Merck & Co., Inc. - Rahway NJ
  • International Classification:
    A61K 3900
    A61K 3912
    A61K 3942
  • US Classification:
    424 86
  • Abstract:
    High purity HB. sub. s Ag is injected into guinea pigs to stimulate formulation of HB. sub. s Ab-positive serum. Gamma globulins containing HB. sub. s Ab are separated from the serum and the globulin fraction containing HB. sub. s Ab is isolated and coupled to a Sepharose gel. HB. sub. s Ag from HB. sub. s Ag-positive plasma is adsorbed on the gel by formation of an HB. sub. s Ab-HB. sub. s Ag complex. HB. sub. s Ag is eluted from the column and dialysed.
  • Method Of Preparing Hepatitis B Core Antigen

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  • US Patent:
    41029968, Jul 25, 1978
  • Filed:
    Apr 20, 1977
  • Appl. No.:
    5/789033
  • Inventors:
    William J. McAleer - Ambler PA
    William J. Miller - North Wales PA
    Edward H. Wasmuth - Telford PA
  • Assignee:
    Merck & Co., Inc. - Rahway NJ
  • International Classification:
    A61K 3912
    C12K 700
  • US Classification:
    424 89
  • Abstract:
    HB. sub. c Ag is prepared by isolating Dane particles by isopycnic banding of fluid from HB. sub. s Ag positive donors, optionally but preferably pelleting the Dane particles, and then removing the surface antigen by contacting the Dane particles with a nonionic surfactant having from about 15 to about 35 oxyethylene units in the presence of a reducing agent such as mercaptoethanol. The isolated core antigen is used as a diagnostic and immunologic agent.
  • Separating Antigen From Residual Common Sensitizing Protein

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  • US Patent:
    40396576, Aug 2, 1977
  • Filed:
    Apr 12, 1976
  • Appl. No.:
    5/676265
  • Inventors:
    William J. McAleer - Ambler PA
    Edward H. Wasmuth - Telford PA
  • Assignee:
    Merck & Co., Inc. - Rahway NJ
  • International Classification:
    A61K 3912
    A61K 3920
    A61K 3900
  • US Classification:
    424 89
  • Abstract:
    Sensitizing plasma protein is dissociated from antigen-plasma protein complex by agitating at low temperature under controlled pH.
  • Hepatitis B Antigen

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  • US Patent:
    41184777, Oct 3, 1978
  • Filed:
    Sep 2, 1977
  • Appl. No.:
    5/830291
  • Inventors:
    William J. McAleer - Ambler PA
    Edward H. Wasmuth - Telford PA
  • Assignee:
    Merck & Co., Inc. - Rahway NJ
  • International Classification:
    A61K 3912
  • US Classification:
    424 89
  • Abstract:
    An improved process for the preparation of hepatitis B antigen by subjecting biological fluid containing heptatitis B surface antigen to isopycanic banding wherein the step gradient is NaBr. Faster and more economical processing is obtained by multiple loading of the step gradient, either NaBr or conventional gradients.
  • Process For Isolating Hepatitis B Antigen

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  • US Patent:
    40242439, May 17, 1977
  • Filed:
    Jun 16, 1975
  • Appl. No.:
    5/587507
  • Inventors:
    William J. McAleer - Ambler PA
    Edward H. Wasmuth - Telford PA
  • Assignee:
    Merck & Co., Inc. - Rahway NJ
  • International Classification:
    A61K 3912
    C12K 500
    C07G 700
  • US Classification:
    424 89
  • Abstract:
    An improved process for the preparation of hepatitis B antigen by subjecting plasma of hepatitis B donors to isopycanic banding wherein the step gradient is NaBr. Faster and more economical processing is obtained by multiple loading of the step gradient, either NaBr or conventional gradients.
  • Hepatitis B Antigen

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  • US Patent:
    41861930, Jan 29, 1980
  • Filed:
    Oct 25, 1977
  • Appl. No.:
    5/845016
  • Inventors:
    William J. McAleer - Ambler PA
    Edward H. Wasmuth - Telford PA
  • Assignee:
    Merck & Co., Inc. - Rahway NJ
  • International Classification:
    A61K 3912
  • US Classification:
    424 89
  • Abstract:
    Hepatitis B surface antigen free of gradient-derived added cesium and potassium ions, for example the antigen in an aqueous solution of sodium bromide.
  • Method For Preparing Hepatitis B Immune Globulin

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  • US Patent:
    41743881, Nov 13, 1979
  • Filed:
    Jul 19, 1978
  • Appl. No.:
    5/925736
  • Inventors:
    William J. McAleer - Ambler PA
    Edward H. Wasmuth - Telford PA
  • Assignee:
    Merck & Co., Inc. - Rahway NJ
  • International Classification:
    A61K 3942
  • US Classification:
    424 86
  • Abstract:
    Hepatitis B immune globulin is prepared from individuals who exhibit an increase in hepatitis B surface antibody of at least 2,000 PHA units/ml following immunization with hepatitis B surface antigen.

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Frank Lloyd Wright's American System-Built Ho...

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President Wendler's Op-Ed: The History of Phi...

For the full op-ed with references, visit .

  • Duration:
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