George Rodger Aronoff

US Patent:

20130085772, Apr 4, 2013

Filed:

Sep 28, 2012

Appl. No.:

13/631112

Inventors:

UNIVERSITY OF LOUISVILLE RESEARCH FOUN - Louisville KY, US
Michael E. Brier - New Albany IN, US
George R. Aronoff - Louisville KY, US
Alfred A. Jacobs - Louisville KY, US

Assignee:

UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. - Louisville KY

International Classification:

G06Q 50/22

US Classification:

705 2

Abstract:

A system and method for personalized dosing of a pharmacologic agent include: executing, using a processing device, a plurality of dosing regimen program modules to determine a respective plurality of dose sets in response to receiving, from an input device, a target response value for a patient; and executing, using the processing device, a dosing selection algorithm module, following executing the plurality of dosing regimen program modules and in response to receiving from the input device a response profile and a monitoring frequency of the patient, to determine a recommended dose set computed as a combination of the plurality of dose sets weighted by degrees of matching computed using fuzzy sets and the response profile.

US Patent:

20210012872, Jan 14, 2021

Filed:

Sep 17, 2020

Appl. No.:

17/024518

Inventors:

- Louisville KY, US
Michael E. BRIER - Rossville TN, US
George R. ARONOFF - Englewood CO, US
Alfred A. JACOBS - Louisville KY, US

Assignee:

University of Louisville Research Foundation, Inc. - Louisville KY

International Classification:

G16H 20/10
A61B 34/10
G16H 50/20
G16H 50/50

Abstract:

A system and method for personalized dosing of a pharmacologic agent include: executing, using a processing device, a plurality of dosing regimen program modules to determine a respective plurality of dose sets in response to receiving, from an input device, a target response value for a patient; and executing, using the processing device, a dosing selection algorithm module, following executing the plurality of dosing regimen program modules and in response to receiving from the input device a response profile and a monitoring frequency of the patient, to determine a recommended dose set computed as a combination of the plurality of dose sets weighted by degrees of matching computed using fuzzy sets and the response profile.

US Patent:

20180101640, Apr 12, 2018

Filed:

Nov 14, 2017

Appl. No.:

15/812666

Inventors:

- Louisville KY, US
Michael E. BRIER - New Albany IN, US
George R. ARONOFF - Louisville KY, US
Alfred A. JACOBS - Louisville KY, US

International Classification:

G06F 19/00

Abstract:

A system and method for personalized dosing of a pharmacologic agent include: executing, using a processing device, a plurality of dosing regimen program modules to determine a respective plurality of dose sets in response to receiving, from an input device, a target response value for a patient; and executing, using the processing device, a dosing selection algorithm module, following executing the plurality of dosing regimen program modules and in response to receiving from the input device a response profile and a monitoring frequency of the patient, to determine a recommended dose set computed as a combination of the plurality of dose sets weighted by degrees of matching computed using fuzzy sets and the response profile.