Leroy B. Townsend - Ann Arbor MI John G. Drach - Ann Arbor MI Charles Shipman - Dexter MI Jeffrey S. Pudlo - Ann Arbor MI
Assignee:
The Regents of the University of Michigan - Ann Arbor MI
International Classification:
A61K 31505 C07D48706
US Classification:
514258
Abstract:
This invention relates to the use of acyclic substituted pyrrolo�2,3-d!pyrimidine nucleoside analogs in the treatment of viral infections. Such substituted compounds retain antiviral properties present in their parent compounds, yet exhibit significantly decreased levels of cytotoxicity, thereby having therapeutic potential as antiviral agents.
Acyclic Pyrrolo [2,3-D]Pyrimidine Analogs As Antiviral Agents
Leroy B. Townsend - Ann Arbor MI John G. Drach - Ann Arbor MI Charles Shipman - Dexter MI Jeffrey S. Pudlo - Ann Arbor MI
Assignee:
The Regents of The University of Michigan - Ann Arbor MI
International Classification:
A61K 31505 C07D48706
US Classification:
514258
Abstract:
This invention relates to the use of acyclic substituted pyrrolo[2,3-d]pyrimidine nucleoside analogs in the treatment of viral infections. Such substituted compounds retain antiviral properties present in their parent compounds, yet exhibit significantly decreased levels of cytotoxicity, thereby having therapeutic potential as antiviral agents.
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Jeffrey Arndt (1970-1973), Judy Clark (1973-1976), Jacqueline Kirk (1993-1997), Jeffrey Pudlo (1990-1994), Kelly Stewart (1984-1986), Dawn Phillips (1981-1984)