John R Shainoff

US Patent:

42751969, Jun 23, 1981

Filed:

Mar 23, 1979

Appl. No.:

6/023179

Inventors:

John R. Shainoff - Cleveland Heights OH

Assignee:

The Cleveland Clinic Foundation - Cleveland OH

International Classification:

B01D 5702
B01J 1300
C07H 1500

US Classification:

536115

Abstract:

A new composition of matter is provided having novel, valuable attributes in the zonal immobilization of proteins of biochemical origin which expands man's capacity to separate, isolate, detect, and sequentially sorb and desorb, concentrate, and quantify and qualify picomole size samples or specimens of complex proteins of biochemical origin into fundamentally interesting fractions for studies to expand the understanding of, illustratively, the complex proteins in lesions of atherosclerosis, antigens, antibodies, enzyme immobilization in studies of enzymatic actions in body tissues and functions, immunoglobulins, genetic aberrations, molecular size separations of complex proteins, and extends the sensitivity of detection of such isolates beyond that achievable by prior art radio immunoassay techniques.

US Patent:

43127274, Jan 26, 1982

Filed:

Sep 30, 1980

Appl. No.:

6/192241

Inventors:

John R. Shainoff - Cleveland Heights OH

Assignee:

The Cleveland Clinic Foundation - Cleveland OH

International Classification:

G01N 2726

US Classification:

204180G

Abstract:

A new composition of matter is provided having novel, valuable attributes in the zonal immobilization of proteins of biochemical origin which expands man's capacity to separate, isolate, detect, and sequentially sorb and desorb, concentrate, and quantify and qualify picomole size samples or specimens of complex proteins of biochemical origin into fundamentally interesting fractions for studies to expand the understanding of, illustratively, the complex proteins in lesions of atherosclerosis, antigens, antibodies, enzyme immobilization in studies of enzymatic actions in body tissues and functions, immunoglobulins, genetic aberrations, molecular size separations of complex proteins, and extends the sensitivity of detection of such isolates beyond that achievable by prior art radio immunoassay techniques.