Johnny C Mounphoxay

US Patent:

20050037484, Feb 17, 2005

Filed:

Apr 21, 2004

Appl. No.:

10/828732

Inventors:

Norbert Staimer - Lake Forest CA, US
YihFar Chen - Kaohsing City, TW
James Norton - Santa Ana CA, US
Jay Jison - Aliso Viejo CA, US
Johnny Mounphoxay - Anaheim CA, US

International Classification:

C12M001/34

US Classification:

435287200, 422058000

Abstract:

The present invention relates to methods and apparatus for assays including optical bio-discs with spiral fluidic circuits and related detection systems. The optical bio-disc includes a cap portion having inlet and vent ports formed therein, a first channel layer having cut-out portions, a second channel layer having cut-out portions; a third channel layer having cut-cut portions, a fourth channel layer having cut-out portions, and a substantially circular substrate having a center and an outer edge. The cut-out portions are in register with each other such that when the bio-disc is assembled a spiral fluidic circuit is formed having an inlet port, a mixing chamber upper flow chambers lower pass through chambers inlet passages outlet passages a circumferential analysis chamber and vent ports in fluid communication.