Juan Jose Marugan - Gaithersburg MD, US Jingbo Xiao - Rockville MD, US Steven A. Titus - Elkridge MD, US Noel Southall - Chevy Chase MD, US Wei Zheng - Potomac MD, US Elliot J. Androphy - Natick MA, US Jonathan Cherry - Worcester MA, US
Assignee:
Secretary, Department of Health and Human Services - Bethesda MD
International Classification:
C07D 417/04
US Classification:
514326, 546209
Abstract:
Aryl substituted thiazol-2-yl-piperidines and related compounds useful as modulators of survival motor neuron (SMN) protein production are provided herein. Without being bound to any particular theory it is believed the aryl substituted thiazol-2-yl-piperidines and related compounds provided herein act to increase production of the SMN2 form of survival motor neuron protein. These compounds are useful for treating spinal muscular atrophy. Pharmaceutical compositions containing a carrier and one or more of the aryl substituted thiazol-2-yl-piperidine or related compounds described herein are also provided. Methods of treating spinal muscular atrophy are also provided by this disclosure.
Youtube
Final Destination 2
[ www.cinemaniaci.... ] di David R. Ellis con AJ Cook, Ali Larter, Mi...
Category:
Film & Animation
Uploaded:
06 Nov, 2009
Duration:
1m 26s
Jonathan Fire*Eater - The Search For Cherry Red
Track one from Tremble Under Boom Lights
Category:
Music
Uploaded:
17 Jan, 2010
Duration:
4m 38s
Cherry Cherry - Jonathan King ( Neil Diamond ...
1970 single from Jonathan King - did not chart in UK. The song had ear...
Category:
Music
Uploaded:
22 Mar, 2010
Duration:
2m 56s
INSTANT MESSAGE
Marvista Entertainment presents: Starring Marla Sokoloff, Patrick Adam...
Category:
Film & Animation
Uploaded:
23 Oct, 2007
Duration:
1m 38s
Actor Jonathan Cherry
Cool fun going for a spin down the Sunset Strip with Jonathan... A qui...
Category:
Entertainment
Uploaded:
27 Jul, 2009
Duration:
7m 52s
Citadel on fire at Cherry Blossom Parade in D...
Category:
Entertainment
Uploaded:
09 Apr, 2011
Duration:
1m 49s
Jonathan Cherry on blogging
Jonathan Cherry (www.cherryflava... was interviewed on Morning Live l...
Category:
People & Blogs
Uploaded:
18 Mar, 2007
Duration:
9m 13s
House Of The Dead Trailer (2003)
A trailer for the film House of the Dead (2003), directed by Uwe Boll ...
Category:
Film & Animation
Uploaded:
26 Jan, 2009
Duration:
1m 53s
Googleplus
Jonathan Cherry
Work:
United Parcel Service - Ramp Secret Agent (2007) Domino's Pizza - Pizza Bitch (2006-10) Zappos.com - Picker (2010-2011)
Education:
University of Louisville - Communications in Broadcasting, Jefferson Community College - Communications
About:
I'm a pretty simple dude. A jack of a few trades...
Tagline:
This is my tagline. There are many others like it, but this one is mine.
Bragging Rights:
Playing a killer slap bass, being full of fun facts.
Jonathan Cherry
About:
I'm Jon. I destroy worlds.
Bragging Rights:
My flasks are sold worldwide.
Jonathan Cherry
Jonathan Cherry
Jonathan Cherry
Jonathan Cherry
Jonathan Cherry
Jonathan Cherry
News
Scientists Spot Marker for CTE in Living Football Players
"Not only did this research show the potential for CTE diagnosis during life, but it also offers a possible mechanism for distinguishing between CTE and other diseases," said study first author Jonathan Cherry, a postdoctoral fellow in neurology at Boston University Medical Center.
Date: Sep 26, 2017
Category: Science
Source: Google
After Gruesome West Hollywood Murder, New Details About Accused Killer Emerge
According to one producer who worked with him on the 2008 film Bald, starring Jonathan Cherry and Sally Kirkland (which went straight to DVD), Leibels eccentricities were a mask. "He was like a big teddy bear," says this producer, "He always wanted everyone to laugh, but his ideas were crazy, out t
e Highlanders lineup includes Jonathan Cherry as the tweaked goaltender ("Two rules: Stay away from my Percocets, and do you have any Percocets?"); George Tchortov and Karl Graboshas as a couple of grab-assy Russians; and Richard Clarkin as the team captain who, in a post-divorce tailspin, spells ou
Angela Kohler, Kaly Spoon, Melissa Wheeler, William Weldin, Gina Stangl, Michael Stuber, Patrick Ritchie, Ryan Bables, Jane Doe, Elisha Estes, Sherryle Bieler