Jose Cosgaya - Stanford CA, US Jonah Chan - Cupertino CA, US Eric Shooter - Stanford CA, US
International Classification:
G01N033/53 G01N033/567
US Classification:
514/002000, 435/007200
Abstract:
Methods are provided for the treatment of demyelinating disease in the central or peripheral nervous system. Myelination is enhanced by administration of agents that are agonists of the p75receptor; and/or that inhibit a Trk receptor, including TrkC receptor. Methods of screening for pharmaceutically active compounds that enhance myelination are also provided.