- BERKELEY CA, US David Kanne - Corte Madera CA, US Leonard Sung - San Mateo CA, US Kelsey Gauthier - Alameda CA, US Laura Hix Glickman - Oakland CA, US Justin Leong - Union City CA, US Sarah M. McWhirter - Albany CA, US
The present invention provides highly active cyclic-di-nucleotide (CDN) immune stimulators that activate DCs via a recently discovered cytoplasmic receptor known as STING (Stimulator of Interferon Genes). In particular, the CDNs of the present invention are provided in the form of a composition comprising one or more cyclic purine dinucleotides induce human STING-dependent type I interferon production, wherein the cyclic purine dinucleotides present in the composition are 2′-fluoro substituted, bis-3′,5′ CDNs, and most preferably one or more 2′,2″-diF-Rp,Rp, bis-3′,5′CDNs.
Internet Marketer and investor despite the crisis...Battle-scarred, frontline business warrior. Passion for business and sales, thousands of projects and how to make them come true. Passion for gettin...
Internet Marketer based in Subang, Malaysia
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University of California, Irvine
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Philip Cleaning Services - Cleaning Technician
Philip Cleaning Services started operation in 1981, almost 30 years in cleaning business. The company specializes in cleaning and restoration for water and fire-damaged carpeting, upholstery, etc.