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Maria A Graziewicz

age ~57

from Chapel Hill, NC

Maria Graziewicz Phones & Addresses

  • 1131 Arborgate Cir, Chapel Hill, NC 27514 • 9199673267
  • 1131 Arborgate Cir APT 130, Chapel Hill, NC 27514 • 9193086591
  • 521 Ashley Ct, Chapel Hill, NC 27514 • 9199673267
  • 3210 Stones Throw Ln, Durham, NC 27713 • 9193619460
  • Warsaw, NC
  • Lemon Grove, CA

Work

  • Company:
    Syneos health (previously inc research/inventiv health)
    Mar 2017
  • Position:
    Associate director, global project management, neuroscience

Education

  • Degree:
    Doctorates, Doctor of Philosophy
  • School / High School:
    Institute of Biochemistry and Biophysics
  • Specialities:
    Molecular Biology

Skills

Clinical Research • Cro • Ctms • Clinical Monitoring • Clinical Trials • Clinical Development • Lifesciences • Edc • Oncology • Sop • Diabetes • Infectious Diseases • Gcp • Molecular Biology • Pharmaceutical Industry • Therapeutic Areas • Drug Development • Ich Gcp • Clinical Data Management • Biotechnology • Biochemistry • Clinical Operations • Protocol

Interests

Novel Drugs • Sci Fi Books and Good Food • Applicable Clinical Research • Clinical Trial Recruitment • Clinical Trial Logistics

Industries

Pharmaceuticals

Us Patents

  • Soluble Tnf Receptors And Their Use In Treatment Of Disease

    view source
  • US Patent:
    20070249538, Oct 25, 2007
  • Filed:
    May 1, 2007
  • Appl. No.:
    11/799117
  • Inventors:
    Peter Sazani - Chapel Hill NC, US
    Maria Graziewicz - Chapel Hill NC, US
    Ryszard Kole - Chapel Hill NC, US
  • International Classification:
    A61K 38/16
    A61K 31/7052
    A61P 29/00
    C07H 21/00
    C07K 14/00
    C12N 1/00
    C12N 15/00
    C12N 15/63
    C12N 5/00
    C12P 21/00
  • US Classification:
    514012000, 435243000, 435320100, 435325000, 435455000, 435069100, 514044000, 530350000, 536022100, 536023500
  • Abstract:
    The present invention relates to tumor necrosis factor (TNF) antagonists and corresponding nucleic acids derived from tumor necrosis factor receptors (TNFRs) and their use in the treatment of inflammatory diseases. These proteins are soluble secreted decoy receptors that bind to TNF and prevent TNF from signaling to cells. In particular, the proteins are mammalian TNFRs that lack exon 7 and which can bind TNF and can act as a TNF antagonist.
  • Soluble Thf Receptors And Their Use In Treatment Of Disease

    view source
  • US Patent:
    20120142759, Jun 7, 2012
  • Filed:
    Oct 19, 2007
  • Appl. No.:
    12/598453
  • Inventors:
    Peter L. Sazani - Chapel Hill NC, US
    Maria Graziewicz - Chapel Hill NC, US
    Ryszard Kole - Chapel Hill NC, US
  • International Classification:
    A61K 31/7088
    A61P 29/00
    C12N 5/02
    C07H 21/04
  • US Classification:
    514 44 R, 536 241, 435375
  • Abstract:
    The present invention relates to splice switching oligonucleotides or splice switching oligomers (SSOs). The preferred SSOs according to the invention target exon 7 of TNFR1 (TNFRSF1A) or TNFR2 (TNFRSF1A) pre-mRNA, typically resulting in the production of TNFR variants which comprise a deletion in part or the entire exon 7 respectfully. SSOs targeting exon 7 are found to result in a soluble form of the TNFR, which has thereputic benefit for treatment of inflammatory diseases. The SSO's are characterized in that they are substantially incapable or incapable of recruiting RNaseH.

Resumes

Maria Graziewicz Photo 1

Associate Director, Global Project Management, Neuroscience

view source
Location:
Raleigh, NC
Industry:
Pharmaceuticals
Work:
Syneos Health (Previously Inc Research/Inventiv Health)
Associate Director, Global Project Management, Neuroscience

Syneos Health Clinical Solutions (Previously Inc Research/Inventiv Health) Apr 2015 - Feb 2017
Senior Project Manager, Global Project Management, Neuroscience

Syneos Health Clinical Solutions (Previously Inc Research/Inventiv Health) May 2010 - Apr 2015
Project Manager, Global Project Management, Neuroscience

Inc Research Nov 2008 - Feb 2010
Global Clinical Developement Specialist

Sarepta Therapeutics Mar 2004 - Oct 2008
Senior Scientist, Discovery Research
Education:
Institute of Biochemistry and Biophysics
Doctorates, Doctor of Philosophy, Molecular Biology
University of Warsaw
University of Warsaw
Bachelors, Bachelor of Science, Biology
Skills:
Clinical Research
Cro
Ctms
Clinical Monitoring
Clinical Trials
Clinical Development
Lifesciences
Edc
Oncology
Sop
Diabetes
Infectious Diseases
Gcp
Molecular Biology
Pharmaceutical Industry
Therapeutic Areas
Drug Development
Ich Gcp
Clinical Data Management
Biotechnology
Biochemistry
Clinical Operations
Protocol
Interests:
Novel Drugs
Sci Fi Books and Good Food
Applicable Clinical Research
Clinical Trial Recruitment
Clinical Trial Logistics

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