Melissa M Vasbinder
age ~47
from Newton Center, MA
- Also known as:
-
- Melissa Marie Vasbinder
- Melissa R
- Phone and address:
- 7 Beecher Pl, Newton, MA 02459
Melissa Vasbinder Phones & Addresses
- 7 Beecher Pl, Newton Center, MA 02459
- Newton, MA
- 218 Canton St, Boston, MA 02116 • 8579911475
- 50 Radnor Rd, Brighton, MA 02135
- 9393 New Sulphur Springs Rd, San Antonio, TX 78263 • 2106492462
- Groton, CT
Us Patents
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Pyridinylquinazolinamine Derivatives And Their Use As B-Raf Inhibitors
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US Patent:20100216791, Aug 26, 2010
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Filed:Aug 15, 2007
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Appl. No.:12/377285
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Inventors:Brian Aquila - Waltham MA, US
Donald J. Cook - Waltham MA, US
Craig Johnstone - Macclesfield, GB
Stephen Lee - Waltham MA, US
Paul Lyne - Waltham MA, US
David Alan Rudge - Macclesfield, GB
Melissa Vasbinder - Waltham MA, US
Haixia Wang - Waltham MA, US -
Assignee:ASTRAZENECA - Södertälje
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International Classification:A61K 31/5377
C07D 401/04
A61K 31/517
A61P 35/00
A61P 35/02
C07D 413/14 -
US Classification:5142345, 544284, 51426621, 544119
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Abstract:The invention relates to chemical compounds of the formula (I) or pharmaceutically acceptable salts thereof, which possess B-Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.
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Substituted Heterocycles And Their Use As Chk1, Pdk1 And Pak Inhibitors
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US Patent:20090275570, Nov 5, 2009
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Filed:Apr 5, 2006
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Appl. No.:11/910358
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Inventors:Kevin Daly - Waltham MA, US
Nicola Heron - Macclesfield, GB
Alexander Hird - Waltham MA, US
Stephanos Ioannidis - Waltham MA, US
James Janetka - Waltham MA, US
Paul Lyne - Waltham MA, US
Jaime Scott - Macclesfield, GB
Dorin Toader - Waltham MA, US
Melissa Vasbinder - Waltham MA, US
Dingwei Yu - Waltham MA, US
Yan Yu - Waltham MA, US -
Assignee:ASTRAZENECA AB - Sodertalje
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International Classification:A61K 31/538
C07D 495/04
A61K 31/4365
A61K 31/5377
A61P 35/00
A61K 31/454
C07D 401/12 -
US Classification:5142305, 546114, 514301, 5142338, 544127, 544105, 514323, 546201
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Abstract:The invention relates to novel compounds of Formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds possess CHK1 kinase inhibitory activity, PDK1 inhibitory activity and Pak kinase inhibitory activity and are accordingly useful in the treatment and/or prophylaxis of cancer.
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Targeted Protein Degradation Of Parp14 For Use In Therapy
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US Patent:20220388985, Dec 8, 2022
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Filed:Jun 18, 2020
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Appl. No.:17/619459
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Inventors:- Cambridge MA, US
Melissa Marie Vasbinder - Newton MA, US
Kevin Wayne Kuntz - Woburn MA, US
Kerren Kalai Swinger - Lexington MA, US
Timothy J.N. Wigle - Cambridge MA, US -
International Classification:C07D 401/14
C07D 417/14
C07D 405/14 -
Abstract:The present invention relates to quinazolinones and related compounds which degrade PARP14 and are useful, for example, in the treatment of cancer and inflammatory diseases.
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Methods Of Treating Inflammatory Diseases
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US Patent:20220265655, Aug 25, 2022
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Filed:Jan 28, 2022
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Appl. No.:17/586962
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Inventors:- Cambridge MA, US
Kevin Wayne Kuntz - Cambridge MA, US
Laurie B. Schenkel - Cambridge MA, US
Kerren Kalai Swinger - Cambridge MA, US
Melissa Marie Vasbinder - Cambridge MA, US -
International Classification:A61K 31/517
A61K 45/06
A61P 1/00 -
Abstract:The present invention relates to use of quinazolinones and related compounds which are inhibitors of PARP14 for the treatment and prevention of an inflammatory disease.
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Quinolines And Azaquinolines As Inhibitors Of Cd38
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US Patent:20220242862, Aug 4, 2022
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Filed:Jan 28, 2022
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Appl. No.:17/586939
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Inventors:- Cambridge MA, US
Kevin Wayne Kuntz - Cambridge MA, US
Laurie B. Schenkel - Cambridge MA, US
Melissa Marie Vasbinder - Cambridge MA, US -
International Classification:C07D 471/04
C07D 401/04
C07D 405/14
C07D 401/14 -
Abstract:The present invention relates to compounds which are inhibitors of CD38 and are useful in the treatment of cancer.
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Screening Methods For Parp Modulators
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US Patent:20220206008, Jun 30, 2022
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Filed:Mar 17, 2022
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Appl. No.:17/697322
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Inventors:- Cambridge MA, US
Danielle J. Blackwell - Medford MA, US
Kevin Wayne Kuntz - Woburn MA, US
Melissa Marie Vasbinder - Newton MA, US
Laurie B. Schenkel - Somerville MA, US
Kerren Kalai Swinger - Lexington MA, US -
International Classification:G01N 33/58
C07D 491/22
C07D 493/10
C07D 495/04
C07F 5/02
G01N 33/573 -
Abstract:The present disclosure is related to methods of identifying Poly(ADP-ribose) polymerases (PARP) inhibitors, and the methods of using PARP probes.
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Quinazolinones As Parp14 Inhibitors
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US Patent:20230018702, Jan 19, 2023
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Filed:Apr 14, 2021
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Appl. No.:17/230099
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Inventors:- Cambridge MA, US
Melissa Marie Vasbinder - Newton MA, US
Kevin Wayne Kuntz - Woburn MA, US
Kerren Kalai Swinger - Lexington MA, US -
International Classification:C07D 405/12
C07D 401/12
C07D 403/12
C07D 401/14
C07D 239/88
A61P 35/00
C07D 405/14
C07D 417/14
C07D 471/04
C07D 409/12
C07D 413/14 -
Abstract:The present invention relates to quinazolinones and related compounds which are inhibitors of PARP14 and are useful, for example, in the treatment of cancer and inflammatory diseases.
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Pyridazinones As Parp7 Inhibitors
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US Patent:20210130342, May 6, 2021
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Filed:Oct 29, 2020
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Appl. No.:17/083442
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Inventors:- Cambridge MA, US
Melissa Marie Vasbinder - Newton MA, US
Kevin Wayne Kuntz - Woburn MA, US -
International Classification:C07D 417/14
C07D 401/14
C07D 403/14
A61P 35/00 -
Abstract:The present invention relates to pyridazinones and related compounds which are inhibitors of PARP7 and are useful in the treatment of cancer.
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Melissa Vasbinder
Melissa Vasbinder
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Jesper Jernelius, Grassel Janice, Lauren Sears Cummings, Charlie Castleman
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