Serene Josiah - Cambridge MA Michael Boisclair - Brookline MA
Assignee:
Mitotix, Inc. - Cambridge MA
International Classification:
C12Q 100 C12Q 148 A61K 3804
US Classification:
435 15
Abstract:
A high throughput enzyme screen has been developed which relies on metal chelate interaction for capture of the product of the enzymatic reaction. In the present assay system, a detectable moiety is attached to a substrate having a chelating capturable moiety, which can be captured by an immobilized metal. Detection is effected due to the presence of a detectable label on the reaction product immobilized on the solid phase. Only signal associated with tagged protein bound to the solid phase is detected. The present assay can reliably measure enzyme activity, and has high reproducibility, which benefits high throughput screening.
Jan 2008 to 2000 Substitute TeacherNASHUA HIGH SCHOOL SOUTH Nashua, NH Jan 2013 to Apr 2013 Student Teaching InternLabCorp Portsmouth, NH Aug 2003 to Sep 2004 HistotechnologistMassachusetts General Hospital Core Biology Unit Charlestown, MA Jun 2000 to Sep 2004 HistotechnologistMassachusetts General Hospital Core Biology Unit Boston, MA Jun 2000 to Aug 2003 Mohs HistotechnologistMassachusetts General Hospital Boston, MA Sep 1997 to Jun 2000 HistotechnologistLawrence General Hospital Lawrence, MA Jul 1996 to Sep 1997 HistotechnologistProScript Inc Cambridge, MA Jun 1995 to Jul 1996 Research AssociatePoultry Research Lab Amherst, MA Jan 1992 to May 1995 Research Technician
Education:
Rivier University Nashua, NH 2013 Master of Education in Secondary Education, BiologyUniversity of Massachusetts Amherst, MA 1995 Bachelor of Science in Animal Science
Skills:
Strong skiils in most areas of histology with 11+ years of experience.