Frank M. Yatsu - Houston TX Nargis A. Alam - Webster TX Syed S. Alam - Webster TX
Assignee:
Research Development Foundation - Carson City NV
International Classification:
A61K 3800 A61K 3803 C07K 1447
US Classification:
514 12
Abstract:
The present invention provides a novel isolated and purified protein that is produced by brain endothelial cells, has a molecular weight of approximately 67 kDa of SDS-PAGE, with the protein being capable of stimulating proliferation of cerebral arteriole smooth muscle cells. Also provided are various methods of using this novel protein or the gene encoding this protein, including methods of treating various cerebrovascular diseases.