Nelson C Yim
age ~91
from Austin, TX
- Also known as:
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- Nelson Maria Yim
- Nelsonc F Yim
- Nelson C Fyi
- Yim F Nelson
- Phone and address:
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8312 Canola Bnd, Austin, TX 78729
5122587774
Nelson Yim Phones & Addresses
- 8312 Canola Bnd, Austin, TX 78729 • 5122587774
- 669 Meadowbrook Ave, Ambler, PA 19002 • 2156465721
- Philadelphia, PA
- 8312 Canola Bnd, Austin, TX 78729 • 5126593277
Education
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Degree:Associate degree or higher
Us Patents
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Novel Heterocycles Useful In The Treatment Of Benign Prostatic Hyperplasia
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US Patent:20020165219, Nov 7, 2002
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Filed:Nov 26, 2001
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Appl. No.:09/994153
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Inventors:Richard Hutchings - Ann Arbor MI, US
Haripada Khatuya - San Diego CA, US
Xiaobing Li - San Diego CA, US
William Murray - Belle Mead NJ, US
Catherine Prouty - Doylestown PA, US
Frank Villani - Perkasie PA, US
Nelson Yim - Ambler PA, US
Cynthia Maryanoff - Forest Grove PA, US -
International Classification:A61K031/496
C 07D 4 3/02 -
US Classification:514/210200, 514/253010, 514/254010, 544/360000, 544/359000, 544/372000
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Abstract:This invention relates a to a series of heterocyclic substituted piperazines of Formula I pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention selectively inhibit binding to the -1a adrenergic receptor, a receptor which has been implicated in benign prostatic hyperplasia. As such the compounds are potentially useful in the treatment of this disease.
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Polypeptide Intermediates
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US Patent:46847162, Aug 4, 1987
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Filed:Apr 16, 1986
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Appl. No.:6/852696
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Inventors:Nelson C. Yim - Ambler PA
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Assignee:SmithKline Beckman Corporation - Philadelphia PA
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International Classification:C07K 716
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US Classification:530328
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Abstract:2- or 3-. beta. -Indolylalanyl and. beta. -indolylglycyl vasopressins are prepared by standard peptide synthetic methods. These 2- or 3-TRP vasopressins have vasopressin antagonist activity.
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Basic Heptapeptide Vasopressin Antagonists
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US Patent:45433496, Sep 24, 1985
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Filed:Aug 28, 1984
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Appl. No.:6/645127
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Inventors:James F. Callahan - Philadelphia PA
Michael L. Moore - Media PA
Nelson C. Yim - Ambler PA -
Assignee:SmithKline Beckman Corporation - Philadelphia PA
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International Classification:A61K 3700
C07C10352 -
US Classification:514 11
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Abstract:Certain cyclic vasopressin-like peptides, which have an. omega. -amino- or guanidinoalkyl substituent attached to the cysteine in the 6-position of the ring, have vasopressin antagonist activity. A species of this series of new compounds is [1-(. beta. -mercapto-. beta. ,. beta. -cyclopentamethylenepropionic acid)-2-(O-ethyl-D-tyrosine)-4-valine-8-(1,5-diaminopentane)-8-desarginine -9-desglycinamide]-vasopressin.
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.Beta.-Indolylalanyl Or .Beta.-Indolylglycinyl Vasopressin Antagonists
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US Patent:45979014, Jul 1, 1986
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Filed:Dec 14, 1984
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Appl. No.:6/681461
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Inventors:Nelson C. Yim - Ambler PA
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Assignee:SmithKline Beckman Corporation - Philadelphia PA
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International Classification:C07K 716
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US Classification:530328
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Abstract:2- or 3-. beta. -Indolylalanyl and. beta. -indolylglycyl vasopressins are prepared by standard peptide synthetic methods. These 2- or 3-TRP vasopressins have vasopressin antagonist activity.
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Substituted 1-Thienyl And Furyl-2,3,4,5-Tetrahydro-1H-3-Benzazepine Compounds
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US Patent:41119576, Sep 5, 1978
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Filed:Feb 2, 1977
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Appl. No.:5/764672
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Inventors:Kenneth George Holden - Haddonfield NJ
Nelson Chi-Fai Yim - Philadelphia PA -
Assignee:SmithKline Corporation - Philadelphia PA
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International Classification:C07D33324
C07D33316
A01N 900 -
US Classification:2603322C
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Abstract:A group of 7,8-dihydroxy-2,3,4,5-tetrahydro-1H-3-benzazepines with structures containing a thienyl or furyl ring at position 1 which have dopaminergic activity. Particular species of this group include 7,8-dihydroxy-1-(5'-methyl-2'-thienyl)-2,3,4,5-tetrahydro-1H-3-benzazepine and its dimethyl ether derivative, 7,8-dihydroxy-1-(2'-thienyl)-2,3,4,5-tetrahydro-1H-3-benzazepine and its dimethyl ether as well as 7,8-dihydroxy-1-(3'-thienyl)-2,3,4,5-tetrahydro-1H-3-benzazepine and its dimethyl ether.
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Method For Preparing Lower Alkyl .Beta.-(S-Benzylmercapto)-.Beta.,.Beta.-Pentamethylenepropionates
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US Patent:42999693, Nov 10, 1981
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Filed:Aug 8, 1980
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Appl. No.:6/176372
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Inventors:William F. Huffman - Malvern PA
Nelson C. Yim - Ambler PA -
Assignee:SmithKline Corporation - Philadelphia PA
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International Classification:C07C14940
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US Classification:560 9
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Abstract:Lower alkyl. beta. -(S-benzylmercapto)-. beta. ,. beta. -pentamethylenepropionates are prepared in improved yields by reacting lower alkyl cyclohexylideneacetates with benzylmercaptan in the presence of an alkali metal mercaptide.
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Basic V.sub.1 -Vasopressin Antagonists
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US Patent:46043780, Aug 5, 1986
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Filed:Nov 21, 1984
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Appl. No.:6/673829
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Inventors:James F. Callahan - Philadelphia PA
William F. Huffman - Malvern PA
Michael L. Moore - Media PA
Nelson C. Yim - Ambler PA -
Assignee:SmithKline Beckman Corporation - Philadelphia PA
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International Classification:C07K 716
A61K 3734 -
US Classification:514 11
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Abstract:Certain vasopressin-like peptides, which have an acyclic unit at position 1 and which have an. omega. -amino- or guanidinoalkyl substituent attached to the cysteine in the 6-position of the ring, have V. sub. 1 -vasopressin and oxytocin antagonist activity. A species of this series of new compounds is [1-desaminopenicillamine-2-(O-ethyl-D-tyrosine)-8-(1,4-diaminobutane)-9-de sglycinamide]-vasopressin.
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Polypeptide Intermediates
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US Patent:46580158, Apr 14, 1987
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Filed:Apr 16, 1986
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Appl. No.:6/852869
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Inventors:James F. Callahan - Philadelphia PA
William F. Huffman - Malvern PA
Michael L. Moore - Media PA
Nelson C. Yim - Ambler PA -
Assignee:SmithKline Beckman Corporation - Philadelphia PA
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International Classification:C07K 706
C07K 716 -
US Classification:530329
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Abstract:Certain vasopressin-like peptides, which have an acyclic unit at position 1 and which have an. omega. -amino- or guanidinoalkyl substituent attached to the cysteine in the 6-position of the ring, have V. sub. 1 -vasopressin and oxytocin antagonist activity. A species of this series of new compounds is [1-desaminopenicillamine-2-(O-ethyl-D-tyrosine)-8-(1,4-diaminobutane)-9-de sglycinamide]-vasopressin.
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