Nobuko Ueda from Napa, CA

Method For Manufacture Of Polyphenols By Using Seeds As Starting Material
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US Patent:

7838051, Nov 23, 2010
Filed:

Sep 10, 2007
Appl. No.:

11/852722
Inventors:

Koji Ochiai - Napa CA, US
Nobuko Ueda - Napa CA, US
Assignee:

Indivi Wine, Ltd. - Okazaki-Shi, Aichi
International Classification:

A61K 36/87
US Classification:

424766
Abstract:

To provide a method for the manufacture of polyphenols that enables industrial manufacture of polyphenols containing water-soluble proanthocyanidins from grape seeds. The seeds of grape berries dried after squeezing out the juice are separated into grape seeds and peel with a separation apparatus, and the grape seeds are stirred in a washing machine to remove contamination thoroughly. The grape seeds are charged into a boiling kettle and heated for the prescribed time at the prescribed temperature. Then, germination is induced in a curing kettle maintained at the prescribed temperature preferred for the germination. The grape seeds in which germination or germination and differentiation have advanced are crushed, mixed with water to obtain an emulsified state, and a salt is added, if desired. After a known desalting treatment has been conducted with respect to an aqueous solution portion, water is evaporated with a vacuum apparatus to obtain polyphenols comprising proanthocyanidins converted to a water soluble form.

Method For Manufacture Of Polyphenols By Using Grape Seeds As Starting Material
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US Patent:

20060153957, Jul 13, 2006
Filed:

Oct 6, 2005
Appl. No.:

11/246442
Inventors:

Koji Ochiai - Napa CA, US
Nobuko Ueda - Napa CA, US
International Classification:

B02B 1/08
US Classification:

426507000
Abstract:

[Task] To provide a method for the manufacture of polyphenols that enables industrial manufacture of polyphenols containing water-soluble proanthocyanidins from grape seeds. [Means of solution] The seeds of grape berries dried after squeezing out the juice are separated into grape seeds and peel with a separation apparatus, and the grape seeds are stirred in a washing machine to remove contamination thoroughly. The grape seeds are charged into a boiling kettle and heated for the prescribed time at the prescribed temperature. Then, germination is induced in a curing kettle maintained at the prescribed temperature preferred for the germination. The grape seeds in which germination or germination and differentiation have advanced are crushed, mixed with water to obtain an emulsified state, and a salt is added, if desired. After a known desalting treatment has been conducted with respect to an aqueous solution portion, water is evaporated with a vacuum apparatus to obtain polyphenols comprising proanthocyanidins converted to a water soluble form.

Germinated Seeds Possessing Increased Water-Soluble Polyphenols And Method Of Manufacturing
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US Patent:

20080003314, Jan 3, 2008
Filed:

Nov 21, 2006
Appl. No.:

11/603604
Inventors:

Koji Ochiai - Napa CA, US
Nobuko Ueda - Napa CA, US
Assignee:

INDIVI WINE USA, LLC - Napa CA
International Classification:

A61K 36/18
A01H 3/00
US Classification:

424776, 47 581 R
Abstract:

A method and apparatus for increased yields of water-soluble polyphenols from plant seeds is provided. The method includes inducing seed germination within a selected range of temperatures. The method also includes inducing germination in an atmosphere having elevated carbon oxygen concentration and/or a reduced concentration of oxygen. The method further includes exposing the seeds to light and extracting water-soluble polyphenols with an aqueous solution without adding an organic solvent such as alcohol.

Germinated Seeds Possessing Increased Water-Soluble Polyphenols And Method Of Manufacturing
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US Patent:

20080008812, Jan 10, 2008
Filed:

Aug 31, 2007
Appl. No.:

11/849213
Inventors:

Koji OCHIAI - Napa CA, US
Nobuko Ueda - Napa CA, US
Assignee:

INDIVI WINE USA, LLC - Napa CA
International Classification:

A23B 9/24
A01C 1/02
US Classification:

426542000, 0470581LS, 0470581SE
Abstract:

A method and apparatus for increased yields of water-soluble polyphenols from plant seeds is provided. The method includes inducing seed germination within a selected range of temperatures. The method also includes inducing germination in an atmosphere having elevated carbon oxygen concentration and/or a reduced concentration of oxygen. The method further includes exposing the seeds to light and extracting water-soluble polyphenols with an aqueous solution without adding an organic solvent such as alcohol.