Qiudeng Que from 623 Halcyon Meadow Dr, Cary, NC 27519, age 59, Phone: 9194607240

Us Patents

Lambda Integrase Mediated Recombination In Plants
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US Patent:

7351877, Apr 1, 2008
Filed:

Mar 28, 2003
Appl. No.:

10/403232
Inventors:

Janet Louise Suttie - Research Triangle Park NC, US
Qiudeng Que - Research Triangle Park NC, US
Assignee:

Syngenta Participations AG - Basel
International Classification:

C12N 15/82
C12N 15/83
C12N 15/84
C12N 15/87
C12N 5/04
A01H 5/00
C12N 15/33
US Classification:

800278, 800287, 435412, 435456, 435462, 435468, 435469, 435470, 536 2372
Abstract:

The present disclosure provides methods for obtaining the targeted integration of a DNA molecule into the genome of a host cell using a recombinase. The methods disclosed herein can be used with a variety of host cells, including, for example, dicotyledonous and monocotyledonous plant cells. The present disclosure provides a method for effecting site-specific recombination of DNA within a plant cell, comprising: introducing into the plant cell a target nucleotide sequence comprising a first Int recognition site; introducing into the plant cell a donor nucleotide sequence comprising a second Int recognition site; and introducing into the plant cell an integrase or integrase complex.

Targeted Integration And Stacking Of Dna Through Homologous Recombination
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US Patent:

7935862, May 3, 2011
Filed:

Dec 1, 2004
Appl. No.:

11/001346
Inventors:

Qiudeng Que - Research Triangle Park NC, US
Assignee:

Syngenta Participations AG - Basel
International Classification:

C12N 15/82
C12N 15/06
C12N 15/63
C12N 15/00
A01H 5/00
US Classification:

800278, 800295, 435455, 435468, 435471
Abstract:

The invention provides various methods for the targeted integration and stacking of nucleotide sequences in the genome of a host plant cell using homologous recombination.

Corn Event Mir162
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US Patent:

8232456, Jul 31, 2012
Filed:

May 24, 2007
Appl. No.:

12/301824
Inventors:

Nykoll Long - Research Triangle Park NC, US
Jeff Bottoms - Research Triangle Park NC, US
Moez Meghji - Bloomington IL, US
Hope Hart - Research Triangle Park NC, US
Qiudeng Que - Research Triangle Park NC, US
Derrick Pulliam - Durham NC, US
Assignee:

Syngenta Participations AG - Basel
International Classification:

C12N 15/82
A01H 1/00
US Classification:

800302, 435419, 536 237, 800266, 800275
Abstract:

A novel transgenic corn event designated MIR162 is disclosed. The invention relates to nucleic acids from event MIR162. The invention also relates to assays for detecting the presence of the MIR162 event based on DNA sequences of the recombinant constructs inserted into the corn genome that resulted in the MIR162 event and of genomic sequences flanking the insertion sites. The invention further relates to corn plants comprising the genotype of MIR162 and to methods for producing a corn plant by crossing a corn plant comprising the MIR162 genotype with itself or another corn variety. Seeds of corn plants comprising the MIR162 genotype are also objects of the present invention. The invention also relates to methods of controlling insects using MIR162 corn plants.

Targeted Integration Of Dna Through Recombination
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US Patent:

8399254, Mar 19, 2013
Filed:

Feb 18, 2011
Appl. No.:

13/030809
Inventors:

Qiudeng Que - Research Triangle Park NC, US
Assignee:

Syngenta Participations AG - Basel
International Classification:

C12N 5/04
C12N 5/07
US Classification:

435419, 435410, 435325, 435468
Abstract:

Host cells comprise a site for targeted integration and iterative stacking of DNA through recombination. The site comprises a target sequence comprising (a) a truncated functional sequence effective for restoration of a functional sequence when operably linked through a recombination event with a sequence that completes the truncated functional sequence; (b) a first recombinase recognition site derived through site-specific recombination-mediated excision of nucleotide sequences flanked by recombinase recognition sequences; and (c) a host homology sequence located between the truncated functional sequence and the first recombinase recognition site derived through site-specific recombination-mediated excision of nucleotide sequences flanked by recombinase recognition sequences.

Corn Event Mir162
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US Patent:

8455720, Jun 4, 2013
Filed:

Mar 16, 2012
Appl. No.:

13/421920
Inventors:

Nykoll Long - Holly Springs NC, US
Jeffrey Bottoms - Research Triangle Park NC, US
Moez Rajabali Meghji - St. Louis MO, US
Hope Hart - Research Triangle Park NC, US
Qiudeng Que - Research Triangle Park NC, US
Derrick Pulliam - Durham NC, US
Assignee:

Syngenta Participations AG - Basel
International Classification:

C12N 15/82
US Classification:

800302
Abstract:

A novel transgenic corn event designated MIR162 is disclosed. The invention relates to nucleic acids that are unique to event MIR162 and to methods for detecting the presence of the MIR162 event based on DNA sequences of the recombinant constructs inserted into the corn genome that resulted in the MIR162 event and of genomic sequences flanking the insertion site. The invention further relates to corn plants comprising the transgenic genotype of MIR162 and to methods for producing a corn plant by crossing a corn plant comprising the MIR162 genotype with itself or another corn variety. Seeds of corn plants comprising the MIR162 genotype are also objects of the present invention. The invention also relates to methods of controlling insects using MIR162 corn plants.

Corn Event Mir162
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US Patent:

8618272, Dec 31, 2013
Filed:

Jun 27, 2012
Appl. No.:

13/534202
Inventors:

Nykoll Long - Holly Springs NC, US
Jeffrey Bottoms - Durham NC, US
Moez Rajabali Meghji - St. Louis MO, US
Hope Hart - Durham NC, US
Qiudeng Que - Durham NC, US
Derrick Pulliam - Durham NC, US
Assignee:

Syngenta Participations AG - Basel
International Classification:

C12N 15/11
C12N 15/32
US Classification:

536 231, 536 2371
Abstract:

A novel transgenic corn event designated MIR162 is disclosed. The invention relates to nucleic acids that are unique to event MIR162 and to methods for detecting the presence of the MIR162 event based on DNA sequences of the recombinant constructs inserted into the corn genome that resulted in the MIR162 event and of genomic sequences flanking the insertion site. The invention further relates to corn plants comprising the transgenic genotype of MIR162 and to methods for producing a corn plant by crossing a corn plant comprising the MIR162 genotype with itself or another corn variety. Seeds of corn plants comprising the MIR162 genotype are also objects of the present invention. The invention also relates to methods of controlling insects using MIR162 corn plants.

Lambda Integrase Mediated Recombination In Plants
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US Patent:

20060130179, Jun 15, 2006
Filed:

Mar 28, 2003
Appl. No.:

10/507758
Inventors:

Janet Suttie - RESEARCH TRIANGLE PARK NC, US
Qiudeng Que - Research Triangle Park NC, US
International Classification:

A01H 1/00
C12N 15/82
C12N 15/87
US Classification:

800280000, 435468000
Abstract:

The present disclosure provides methods for obtaining the targeted integration of a DNA molecule into the genome of a host cell using a recombinase. The methods disclosed herein can be used with a variety of host cells, including for example, dicotyledonous and monocotyledonous plant cells. The present disclosure provides a method for effecting site-specific recombination of DNA within a plant cell, comprising: introducing into the plant cell a target nucleotide sequence comprising a first Int recognition site; introducing into the plant cell a donor nucleotide sequence comprising a second Int recognition site. ; and introducing into the plant cell an integrase or integrase complex.

Transformation Of Immature Soybean Seeds Through Organogenesis
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US Patent:

20080229447, Sep 18, 2008
Filed:

Mar 12, 2007
Appl. No.:

11/716975
Inventors:

YuehJiang Hwang - Chapel Hill NC, US
John Dawson - Greensboro NC, US
Marina Sigareva - Chapel Hill NC, US
Qiudeng Que - Cary NC, US
Assignee:

Syngenta Participations AG - Basel
International Classification:

A01H 5/00
C12N 15/87
C12N 5/04
US Classification:

800279, 800278, 800294, 800312
Abstract:

The present disclosure provides methods for the transformation of soybean cells or tissue and regeneration of the soybean cells or tissue into transformed plants. The disclosed methods utilize an explant prepared from an immature soybean seedling which can be induced directly to form shoots that give rise to transgenic plants via organogenesis. The disclosed methods do not require germination and are rapid and efficient.