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Us Patents
Bmp-9 Compositions And Methods For Inducing Differentiation Of Cholinergic Neurons
Jan Blusztajn - Cambridge MA, US Raul Krauss - Cambridge MA, US R. Thies - Andover MA, US
International Classification:
A61K038/17
US Classification:
514012000
Abstract:
BMP-9 compositions and methods for their use are disclosed. The BMP-9 compositions act as a differentiating factor for the cholinergic phenotype of CNS neurons. The compositions may be used in the treatment of diseases and disorders caused by degeneration and/or malfunctioning of cholinergic neurons.
Cell Adhesion-Mediating Proteins And Polynucleotides Encoding Them
Karen Stark - Arlington MA, US Alix Weaver - Northbridge MA, US Heidi Hoffmann - Lunenberg MA, US Raul Krauss - Newton MA, US Kulvinder Saini - Haryana, IN Dario Valenzuela - Houston TX, US
The present invention provides multiple polynucleotide sequences from the same novel gene, the exons comprising the polynucleotide sequences, and the proteins encoded by the polynucleotide sequences. Three splicing variant polynucleotides were isolated from prostate tissue. The polypeptides, including the splicing variants, have a region of hydrophobicity indicative of a transmembrane domain and all three extracellular and cytoplasmic domains.
Vertex Pharmaceuticals Jan 2007 - 2016
Head: Multiple Sclerosis Disease Area Team
Vertex Pharmaceuticals Mar 1, 2014 - 2016
Co-Head North America, Neurology Disease Area Team
Disarm Therapeutics Mar 1, 2014 - 2016
Vice President and Co-Founder | Head of Biology
Vertex Pharmaceuticals 2007 - 2012
Research Scientist and Senior Research Scientist
Biogen 2005 - 2005
Research Scientist, Neurobiology and Molecular Discovery
Education:
Harvard Business School Online 2016 - 2016
Harvard University 1997
Doctorates, Doctor of Philosophy, Neuroscience
Harvard Business School Online 1975 - 1980
Harvard University;Phd, Neuroscience;1997;
Doctorates, Doctor of Philosophy, Neuroscience
Harvard Medical School
Skills:
Drug Discovery Biotechnology Neuroscience Pharmaceutical Industry Neurology Neurobiology Life Sciences Cell Biology Research Molecular Biology Consulting R&D Cell Immunohistochemistry In Vivo Cell Culture Drug Development Pharmacology Lifesciences Clinical Development Assay Development Clinical Research Immunology Mammalian Cell Culture Glia Research and Development
Languages:
English Spanish French
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