Robert J Sacchiero

US Patent:

20070098678, May 3, 2007

Filed:

Jun 26, 2006

Appl. No.:

11/475385

Inventors:

Hitesh Bhagat - Wayland MA, US
Joanne Donovan - Needham MA, US
William Braunlin - Arlington MA, US
Robert Sacchiero - Hudson MA, US

International Classification:

A61K 31/785
A61K 9/20

US Classification:

424078270, 424464000

Abstract:

Tablets, capsules, sachets, or papers having one or more aliphatic amine polymers allow for the targeted release of the polymers at a specific region of the gastrointestinal tract, especially the small intestine. These tablets, capsules, sachets, or papers are useful in a method for lowering cholesterol in a mammal in need thereof. The tablet includes a tablet core having an aliphatic amine polymer, and an enteric coating for the core. The capsule, sachet or paper includes a plurality of beads where the beads have a bead core having an aliphatic amine polymer, an enteric coating therefor and optionally a water-soluble coating.