Robert C Sparks

US Patent:

47634855, Aug 16, 1988

Filed:

May 29, 1987

Appl. No.:

7/055369

Inventors:

Robert L. Sparks - Sarasota FL

International Classification:

F25B 1300
F25D 1900

US Classification:

62160

Abstract:

Inside and outside electrical control adaptors are provided for the installation of heat pump systems where only two or three conductors extend between the inside components and the outside components of the system. The inside adaptor has two relays which provide alternate circuits between the inside to outside conductors and the indoor control wiring. The outside adaptor similarly provides alternate circuits between the inside to outside conductors and the outdoor control wiring.

US Patent:

20180271867, Sep 27, 2018

Filed:

Mar 26, 2018

Appl. No.:

15/936326

Inventors:

Denise Ratzlaff Cooper - St. Petersburg FL, US
Ryan Adam Kirchoffer - Ocala FL, US
Robert Pleasants Sparks - Urbana IL, US
Wayne Charles Guida - Saint Pete Beach FL, US

International Classification:

A61K 31/517
A61K 31/473
A61P 3/04

Abstract:

Disclosed herein are compositions and methods for transitioning or converting a white adipocyte to a beige adipocyte. The compositions and methods may be used in the treatment of obesity. In some embodiments, the compositions include a compound selected from DC677 and DC761.

US Patent:

20160287554, Oct 6, 2016

Filed:

Apr 1, 2016

Appl. No.:

15/088785

Inventors:

Wayne Charles Guida - St. Petersburg Beach FL, US
Robert Pleasants Sparks - Tampa FL, US
Kenyon Gregory Daniel - Wesley Chapel FL, US
Rainer Scott Metcalf - Palm Harbor FL, US
Sreya Mukherjee - Tampa FL, US
Wesley Harrell Brooks - Safety Harbor FL, US

Assignee:

University of South Florida - Tampa FL

International Classification:

A61K 31/343
A61K 31/27
G06F 19/16
A61K 31/366
A61K 31/353
A61K 31/50
A61K 9/00
A61K 31/192

Abstract:

A cancer treatment comprises the administration of a pro-drug compound identified by an in silico candidate identification screening. The pro-drug candidates are selected from a data base and calculations are carried out on the association of the pro-drug candidates to form a complex with a metal ion and a proteasome active site. The pro-drug inhibits the active site of the proteasome in the presence of the metal ion and has little or no effect in the absence of the metal ion. The pro-drug can be: 3,4-dihydroxybenzoic acid; galloflavin; 2-{[(carbamoylsulfanyl)acetyl]amino}benzoic acid; 6,7-Dihydroxycoumaranone; 3,6-bis(hydroxymethyl)pyridazin-4(1H)-one; and 4′,5,7-trihydroxyisoflavone, for binding with copper ion and proteasome.

Author:

Robert A. Sparks

ISBN #:

0399528652