Roberto M Risi

US Patent:

20200010480, Jan 9, 2020

Filed:

Sep 18, 2019

Appl. No.:

16/575114

Inventors:

- North Chicago IL, US
- Wiesbaden, DE
Yujia Dai - Gurnee IL, US
George A. Doherty - Libertyville IL, US
Jane Gong - Deerfield IL, US
Katja Jantos - Wiesbaden, DE
Cheng Ji - Buffalo Grove IL, US
Andrew S. Judd - Grayslake IL, US
Aaron R. Kunzer - Arlington Heights IL, US
Chunqiu Lai - Libertyville IL, US
Anthony Mastracchio - Libertyville IL, US
Roberto M. Risi - Pleasant Prairie WI, US
Xiaohong Song - Grayslake IL, US
Andrew J. Souers - Libertyville IL, US
Gerard M. Sullivan - Libertyville IL, US
Zhi-Fu Tao - Vernon Hills IL, US
Jesse A. Teske - Lake Bluff IL, US
Xilu Wang - Libertyville IL, US
Michael D. Wendt - Vernon Hills IL, US
Yiyun Yu - Lake Bluff IL, US
Guidong Zhu - Gurnee IL, US
Thomas D. Penning - Elmhurst IL, US

Assignee:

AbbVie Inc. - North Chicago IL

International Classification:

C07D 498/18
A61P 35/00
C07D 519/00
C07D 495/18
C07D 495/16

Abstract:

The present disclosure provides for compounds of Formula (I)wherein A, A, A, A, A, A, A, R, R, R, R, R, R, R, R, R, R, W, X, and Y have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents for the treatment of diseases and conditions, including cancer. Also provided are pharmaceutical compositions comprising compounds of Formula (I).

US Patent:

20190055264, Feb 21, 2019

Filed:

Aug 15, 2018

Appl. No.:

15/998688

Inventors:

- North Chicago IL, US
- Wiesbaden, DE
Yujia Dai - Gurnee IL, US
George A. Doherty - Libertyville IL, US
Jane Gong - Deerfield IL, US
Katja Jantos - Wiesbaden, DE
Cheng Ji - Buffalo Grove IL, US
Andrew S. Judd - Grayslake IL, US
Aaron R. Kunzer - Arlington Heights IL, US
Chunqiu Lai - Libertyville IL, US
Anthony Mastracchio - Libertyville IL, US
Roberto M. Risi - Pleasant Prairie WI, US
Xiaohong Song - Grayslake IL, US
Andrew J. Souers - Libertyville IL, US
Gerard M. Sullivan - Libertyville IL, US
Zhi-Fu Tao - Vernon Hills IL, US
Jesse A. Teske - Lake Bluff IL, US
Xilu Wang - Libertyville IL, US
Michael D. Wendt - Vernon Hills IL, US
Yiyun Yu - Lake Bluff IL, US
Guidong Zhu - Gurnee IL, US
Thomas D. Penning - Elmhurst IL, US

International Classification:

C07D 498/18
C07D 495/18
C07D 519/00
A61P 35/00

Abstract:

The present disclosure provides for compounds of Formula (I)wherein A, A, A, A, A, A, A, R, R, R, R, R, R, R, R, R, R, W, X, and Y have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents for the treatment of diseases and conditions, including cancer. Also provided are pharmaceutical compositions comprising compounds of Formula (I).

US Patent:

20160060257, Mar 3, 2016

Filed:

Mar 13, 2014

Appl. No.:

14/780018

Inventors:

- North Chicago IL, US
Milan Bruncko - Green Oaks IL, US
Richard F. Clark - Gurnee IL, US
Michael Curtin - Pleasant Prairie WI, US
Alan S. Florjancic - Kenosha WI, US
Robin R. Frey - Libertyville IL, US
Jianchun Gong - Deerfield IL, US
Todd M. Hansen - Grayslake IL, US
Zhiqin Ji - Libertyville IL, US
Chunqiu Lai - Libertyville IL, US
Anthony Mastracchio - Vernon Hills IL, US
Michael Michaelides - Libertyville IL, US
Juliem Miyashiro - Morton Grove IL, US
Roberto M. Risi - Kenosha WI, US
Xiaohong Song - Grayslake IL, US
Zhi-fu Tao - Vernon Hills IL, US
Keith W. Woods - Lincolnshire IL, US
Guidong Zhu - Gurnee IL, US
Thomas Penning - Elmhurst IL, US
Andrew Souers - Libertyville IL, US
Rajeev Goswami - Dehradun, IN
Omprakash Reddy Iquturi - Guntur, IN
Madhu Babu Dabbeeru - Srikakulam, IN

Assignee:

ABBVIE INC. - North Chicago IL

International Classification:

C07D 471/04
A61K 31/5377
A61K 31/437
A61K 31/4545

Abstract:

Disclosed are compounds of Formula (IIa),wherein R, R, R, R, R, R, R, and Rare as defined in the specification, and pharmaceutically acceptable salts thereof. The compounds may be used as agents in the treatment of diseases, including cancer. Also provided are pharmaceutical compositions comprising one or more compounds of Formula (IIa).