Embodiments of the present technique facilitate the detection of analytes. Detection is generally achieved by binding agents labeled with non-radiative energy transfer acceptors. The binding agents, when bound to a specific analyte, change conformation such that the distance between the respective non-radiative energy transfer acceptors and a respective quantum dot or quantum well changes. Certain embodiments of the present technique also comprise readout circuitry configured to determine rates of non-radiative energy transfer electrically and not optically.
Wen Li - Clifton Park NY, US George Possin - Schenectady NY, US Gregory Zeman - Waukesha WI, US James Leblanc - Niskayuna NY, US Jonathan Short - Saratoga Springs NY, US Rogerio Rodrigues - Clifton Park NY, US
International Classification:
G01T 1/24
US Classification:
250370140
Abstract:
In accordance with an implementation of the present technique, a detector is disclosed. The detector includes a photodetector array and a substrate layer. The photodetector array includes a plurality of photodiodes and a structure of trenches or diffusions grids that electrically isolate each photodiode of the plurality of photodiodes. The plurality of photodiodes and the structure of trenches or deep diffusions grids are disposed on a first surface of the photodetector array and a second surface opposite the first surface is bonded to a substrate layer. The substrate layer is typically made of the same semiconductor material as the photodetector array but heavily doped and conductive to provide cathode contact to the photodetector array in addition to mechanical support.
Photon Counting Ct Detector Using Solid-State Photomultiplier And Scintillator
Jonathan D. Short - Saratoga Springs NY, US George E. Possin - Niskayuna NY, US James W. LeBlanc - Niskayuna NY, US Rogerio G. Rodrigues - Clifton Park NY, US Kent C. Burr - Latham NY, US Aaron J. Couture - Schenectady NY, US Wen Li - Clifton Park NY, US
Assignee:
General Electric Company - Niskayuna NY
International Classification:
A61B 6/00
US Classification:
378 19, 378 988, 25037011
Abstract:
A detector module for a CT imaging system includes a scintillator to convert x-rays to optical photons. The scintillator is optically coupled to a solid-state photomultiplier with internal gain to receive the optical photons and convert them into a corresponding electrical signal output.
Niantic-Harristown High School Niantic IL 1990-1994
Community:
Jason Quinlan, Anna Leonard, Robert Anderson, Amanda Stoffer, Destiny Moran, Michelle Timmons, Pamela Conaway, Elizabeth Mitchell, Tony Gillibrand, Jennifer Bolyard, Michelle Laswell