Scott C. Fahrenkrug - Minneapolis MN, US Daniel F. Carlson - Inner Grove Heights MN, US
Assignee:
Recombinetics, Inc. - Minneapolis MN
International Classification:
C12N 5/16 C12N 5/07 C12N 15/63
US Classification:
435455, 435347
Abstract:
Swine animal models comprising a genomic disruption of an endogenous gene chosen from the group consisting of a Low-Density Lipoprotein Receptor gene LDLR, Duchene's Muscular Dystrophy (DMD) gene, and hairless gene (HR). Methods of preparing transfected cells useful for making a transgenic animal comprising exposing a first group of cells to a transfection agent and reseeding the group with additional cells that have not been exposed to the agent. The transgenic animals are useful for medical and scientific animal models of human diseases and conditions, as well as sources for cells, tissues, and biomaterials.
Using Cytosine Deaminases To Diminish Retroelement Transfer From Pigs To Humans
REUBEN S. HARRIS - ST. PAUL MN, US STEFAN R. JONSSON - KOPAVOGUR, IS SCOTT C. FAHRENKRUG - MINNEAPOLIS MN, US REBECCA ST. CLAIRE LARUE - LAUDERDALE MN, US
Assignee:
REGENTS OF THE UNIVERSITY OF MINNESOTA - SAINT PAUL MN
International Classification:
A01K 67/027
US Classification:
800 17
Abstract:
Transgenic pigs that express one or more non-porcine cytosine deaminases are described as well as methods of making and using such pigs.
Scott C. Fahrenkrug - Minneapolis MN, US Karl J. Clark - Rochester MN, US Daniel F. Carlson - Inver Grove Heights MN, US Michael J. Leaver - Stirling, GB
International Classification:
C12N 15/85 C12N 9/12 C07H 21/00 C12N 5/00
US Classification:
435455, 435194, 536 232, 435325
Abstract:
This document describes the Passport transposon system and methods of making and using the same.
Using Cytosine Deaminases To Diminish Retroelement Transfer From Pigs To Humans
Reuben S. Harris - St. Paul MN, US Stefan R. Jonsson - Kopavogur, IS Scott C. Fahrenkrug - Minneapolis MN, US Rebecca St. Claire Larue - Lauderdale MN, US
International Classification:
A01K 67/00 C12N 5/10
US Classification:
800 17, 435325
Abstract:
Transgenic pigs that express one or more non-porcine cytosine deaminases are described as well as methods of making and using such pigs.
Methods And Compositions For Targeted Gene Modification
Disclosed herein are methods and compositions for gene targeting utilizing fusion molecules comprising a recombinase domain and a sequence-specific DNA-binding domain.
Methods And Materials For Producing Transgenic Artiodactyls
Scott C. Fahrenkrug - Minneapolis MN, US Daniel F. Carlson - Inver Grove Heights MN, US
International Classification:
A01K 67/027 C12N 5/07 C12N 5/10 C12N 15/87
US Classification:
800 9, 800 17, 435325, 435455
Abstract:
Swine animal models comprising a genomic disruption of an endogenous gene chosen from the group consisting of a Low-Density Lipoprotein Receptor gene LDLR, Duchene's Muscular Dystrophy (DMD) gene, and hairless gene (HR). Methods of preparing transfected cells useful for making a transgenic animal comprising exposing a first group of cells to a transfection agent and reseeding the group with additional cells that have not been exposed to the agent. The transgenic animals are useful for medical and scientific animal models of human diseases and conditions, as well as sources for cells, tissues, and biomaterials.
CEO and Chairman of the Board at Recombinetics, Inc., Co-founder and Board Member at Miinome, Inc., Associate Professor at University of Minnesota
Location:
Greater Minneapolis-St. Paul Area
Industry:
Biotechnology
Work:
Recombinetics, Inc. since Sep 2008
CEO and Chairman of the Board
Miinome, Inc. - Greater Minneapolis-St. Paul Area since Jul 2012
Co-founder and Board Member
University of Minnesota since Apr 2001
Associate Professor
Spring Point Project 2003 - 2007
Founder and Chief Scientific Officer
USDA-ARS 1997 - 2001
Geneticist
Education:
University of Minnesota-Twin Cities 1991 - 1996
Ph.D., Molecular, Cellular, Developmental Biology and Genetics
University of Minnesota-Twin Cities 1986 - 1991
B.S., Genetics & Cell Biology, Microbiology
would not have to be removed during slaughter, an efficiency for meatpackers. Recombinetics CEO Scott Fahrenkrug says the project is in a holding pattern as investors eye the lengthy salmon approval process, but he says technologies like his will be necessary as global population is set to increase.