Sherrol H Mcdonough from 5005 Maynard St, San Diego, CA 92122, age 68, Phone: 8584574286

Us Patents

Methods For Making Oligonucleotide Probes For The Detection And/Or Quantitation Of Non-Viral Organisms
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US Patent:

6512105, Jan 28, 2003
Filed:

Jun 30, 2000
Appl. No.:

09/609475
Inventors:

James John Hogan - San Diego CA
Richard Dana Smith - San Diego CA
Jo Ann Kop - San Marcos CA
Sherrol Hoffa McDonough - San Diego CA
Assignee:

Gen-Probe Incorporated - San Diego CA
International Classification:

C07H 2100
US Classification:

536 243, 435 6, 436501, 536 231, 536 2431, 536 2432, 536 253, 702 20
Abstract:

A method for preparing probes, as well as several probes for use in qualitative or quantitative hybridization assays are disclosed. The method comprises constructing an oligonucleotide that is sufficiently complementary to hybridize to a region of rRNA selected to be unique to a non-viral organism or group of non-viral organisms sought to be detected, said region of rRNA being selected by comparing one or more variable region rRNA sequences of said non-viral organism or group of non-viral organisms with one or more variable region rRNA sequences from one or more non-viral organisms sought to be distinguished. Hybridization assay probes for , the -complex bacteria, , Legionella, Salmonella, , Campylobacter, , Enterococcus, , Pseudomonas group I, , bacteria, and fungi also are disclosed.

Hybridization Assay Probes And Methods For Detecting The Presence Of Neisseria Meningitiidis Subtypes A, C And L In A Sample
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US Patent:

6541201, Apr 1, 2003
Filed:

Sep 13, 1999
Appl. No.:

09/394175
Inventors:

Yeasing Yang - San Diego CA
Gary Bee - Vista CA
Sherrol McDonough - San Diego CA
Assignee:

Gen-Probe Incorporated - San Diego CA
International Classification:

C12Q 168
US Classification:

435 6, 435 912, 536 231, 536 243
Abstract:

The present invention discloses hybridization assay probes, amplification primers, nucleic acid compositions and methods useful for detecting Neisseria nucleic acids. Hybridization assay probes and amplification primers that selectively detect and distinguish those from are disclosed. Other hybridization probes selectively detect and not are also described.

Detection Of Hiv
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US Patent:

6589734, Jul 8, 2003
Filed:

Oct 8, 1998
Appl. No.:

09/168947
Inventors:

Daniel L. Kacian - San Diego CA
Timothy J. Fultz - Pleasant Hill CA
Sherrol H. McDonough - San Diego CA
Assignee:

Gen-Probe Incorporated - San Diego CA
International Classification:

C07H 2104
US Classification:

435 6, 435 912, 435 9121, 536 231, 536 2432
Abstract:

The present invention related to oligonucleotides for use in amplifying and detecting HIV nucleic acid in a sample.

Detection Of Hiv-1 By Nucleic Acid Amplification
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US Patent:

6623920, Sep 23, 2003
Filed:

Jul 7, 2000
Appl. No.:

09/611627
Inventors:

Gary G. Bee - Vista CA
Yeasing Y. Yang - San Diego CA
Dan Kolk - Ramona CA
Cristina Giachetti - Solana Beach CA
Sherrol H. McDonough - San Diego CA
Assignee:

Gen-Probe Incorporated - San Diego CA
International Classification:

C12Q 170
US Classification:

435 5, 435 6, 435 912, 536 231, 536 243
Abstract:

Nucleic acid sequences and methods for detecting HIV-1 nucleic acid (LTR and pol sequences) in biological samples by detecting amplified nucleic acids are disclosed. Kits comprising nucleic acid oligomers for amplifying HIV-1 nucleic acid present in a biological sample and detecting the amplified nucleic acid are disclosed.

Detection Of Human Immunodeficiency Virus Type 1
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US Patent:

6649749, Nov 18, 2003
Filed:

Jan 20, 2001
Appl. No.:

09/766095
Inventors:

Sherrol H. McDonough - San Diego CA
Thomas B. Ryder - Escondido CA
Yeasing Yang - San Diego CA
Assignee:

Gen-Probe Incorporated - San Diego CA
International Classification:

C07H 2104
US Classification:

536 2432, 536 2433, 435810
Abstract:

Amplification oligonucleotides and hybridization assay probes which distinguish Human Immunodeficiency Virus type 1 from other viruses.

Oligonucleotides For Nucleic Acid Amplification And For The Detection Of
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US Patent:

7009041, Mar 7, 2006
Filed:

Jun 6, 1995
Appl. No.:

08/480472
Inventors:

Sherrol H. McDonough - San Diego CA, US
Daniel L. Kacian - San Diego CA, US
Nanibhushan Dattagupta - San Diego CA, US
Diane L. McAllister - San Diego CA, US
Philip W. Hammond - San Diego CA, US
Thomas B. Ryder - Escondido CA, US
Assignee:

Gen-Probe Incorporated - San Diego CA
International Classification:

C07H 21/00
C12Q 1/68
C12P 19/34
US Classification:

536 231, 435 6, 435 912, 536 243, 536 2433
Abstract:

A method, composition and kit for synthesizing multiple copies of a target nucleic acid sequence autocatalytically under conditions of substantially constant temperature, ionic strength, and pH are provided in which multiple RNA copies of the target sequence autocatalytically generate additional copies using a mixture of blocked and unblocked primers and/or promoter-primers to initiate DNA and RNA synthesis, preferably with reduced non-specific product formation. The invention is useful for generating copies of a nucleic acid target sequence for purposes that include assays to quantitate specific nucleic acid sequences in clinical, environmental, forensic and similar samples, cloning and generating probes.

Detection Of Hiv
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US Patent:

7083922, Aug 1, 2006
Filed:

Sep 16, 2002
Appl. No.:

10/244490
Inventors:

Daniel L. Kacian - San Diego CA, US
Timothy J. Fultz - Pleasant Hill CA, US
Sherrol H. McDonough - San Diego CA, US
Assignee:

Gen-Probe Incorporated - San Diego CA
International Classification:

C07H 21/04
C12Q 1/68
US Classification:

435 6, 435 912, 435 9121, 536 231, 536 2432
Abstract:

The present invention relates to oligonucleotides for use in amplifying and detecting HIV nucleic acid in a sample.

Oligonucleotide Probes For The Detection And/Or Quantitation Of Non-Viral Organisms
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US Patent:

7087742, Aug 8, 2006
Filed:

May 31, 1995
Appl. No.:

08/455977
Inventors:

James John Hogan - Coronado CA, US
Richard Dana Smith - Victoria, CA
JoAnn Kop - Fremont CA, US
Sherrol Hoffa McDonough - San Diego CA, US
Assignee:

Gen-Probe Incorporated - San Diego CA
International Classification:

C07H 21/02
C07H 21/04
C12Q 1/68
US Classification:

536 243, 536 2432, 536 253, 435 6
Abstract:

A method for preparing probes, as well as several probes for use in qualitative or quantitative hybridization assays are disclosed. The method comprises constructing an oligonucleotide that is sufficiently complementary to hybridize to a region of rRNA selected to be unique to a non-viral organism or group of non-viral organisms sought to be detected, said region of rRNA being selected by comparing one or more variable region rRNA sequences of said non-viral organism or group of non-viral organisms with one or more variable region rRNA sequences from one or more non-viral organisms sought to be distinguished. Hybridization assay probes for , the -complex bacteria, group I, , bacteria, and fungi also are disclosed.

Resumes

Senior Program Manager

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Location:

36 east 41St Pl, San Mateo, CA 94403

Industry:

Biotechnology

Work:

Mcdonough Consultancy 2012 - May 2013
Consultant
Thermo Fisher Scientific 2012 - May 2013
Senior Program Manager
Premier Research 2012 - Nov 2012
Clinical In Vitro Diagnostics Consultant
Hologic (Formerly Gen-Probe) 2011 - 2012
Director, Clinical Program Management
Hologic (Formerly Gen-Probe) 2008 - 2010
Clinical Affairs, Scientist, Director

Education:

Uc San Diego 2008 - 2013
Uc San Diego 1978 - 1985
Doctorates, Doctor of Philosophy, Molecular Biology, Biology, Virology The Collins College of Hospitality Management at Cal Poly Pomona 1974 - 1978
Bachelors, Bachelor of Science, Microbiology

Skills:

Biotechnology
Fda
Assay Development
Medical Devices
Clinical Trials
Design Control
Molecular Biology
Cross Functional Team Leadership
Lifesciences
Program Management
Molecular Diagnostics
Commercialization
Validation
Infectious Diseases
Technology Transfer
Clinical Development
R&D
Genomics
Clinical Research
Team Management
Teamwork
Biomarkers
In Vitro
Dna Sequencing
V&V
Hardware Diagnostics
Sop
Life Sciences
Glp
Oncology
Drug Development
Gmp
Cancer
Biochemistry
Pcr
Microbiology
Regulatory Submissions
Gcp
Research and Development
U.s. Food and Drug Administration

Certifications:

University of California, San Diego
Clinical Trial Design and Management

Sherrol H Mcdonough

Sherrol Mcdonough Phones & Addresses

Work

Education

Skills

Ranks

Industries

Us Patents

Methods For Making Oligonucleotide Probes For The Detection And/Or Quantitation Of Non-Viral Organisms

Hybridization Assay Probes And Methods For Detecting The Presence Of Neisseria Meningitiidis Subtypes A, C And L In A Sample

Detection Of Hiv

Detection Of Hiv-1 By Nucleic Acid Amplification

Detection Of Human Immunodeficiency Virus Type 1

Oligonucleotides For Nucleic Acid Amplification And For The Detection Of

Detection Of Hiv

Oligonucleotide Probes For The Detection And/Or Quantitation Of Non-Viral Organisms

Resumes

Senior Program Manager