A method of antibiotic treatment combines a pore-forming agent with histones, which stabilize the pores and inhibit transcription. This combination has a significant and complete effect on eliminating bacterial growth. A composition comprising a pore-forming agent and a histone, and optionally, a pharmaceutically acceptable carrier or excipient. The pore-forming agents can include LL-37, magainin, or polymyxin B. Examples of a histone include H2A and H3. A method for killing bacteria comprises contacting bacteria with a pore-forming agent and a histone, or with a composition of the invention. Also provided is a method for treating a bacterial infection in a subject, the method comprising administering a pore-forming agent and a histone to the subject, such as in the form of a composition of the invention. In some embodiments, the bacteria comprise , and/or
Isbn (Books And Publications)
Ethical Educational Leadership In Turbulent Times: (Re) Solving Moral Dilemmas
Senior Scientist at Janssen/Veridex, Pharmaceutical Companies of Johnson and Johnson
Location:
Huntingdon Valley, Pennsylvania
Industry:
Pharmaceuticals
Work:
Janssen/Veridex, Pharmaceutical Companies of Johnson and Johnson since Aug 2008
Senior Scientist
Education:
Temple University 1984 - 1987
Masters, Biology
University of the Sciences in Philadelphia 1980 - 1984
BS, Biology
Central High School 1976 - 1980
Honor & Awards:
Johnson and Johnson Leadership Award in recognition of achieving exceptional business results, 2011.
Johnson and Johnson Leadership Award in recognition of achieving exceptional business results, 2012.
Dr. Gross graduated from the Boston University School of Medicine in 1972. He works in San Diego, CA and specializes in Cardiovascular Disease and Internal Medicine. Dr. Gross is affiliated with Alvarado Hospital LLC, Scripps Mercy Hospital and Sharp Grossmont Hospital.
Central Carolina SurgeryCentral Carolina Surgery PA 1002 N Church St STE 302, Greensboro, NC 27401 3363878100 (phone), 3363878200 (fax)
Education:
Medical School Eastern Virginia Medical School Medical College Graduated: 1996
Procedures:
Destruction of Lesions on the Anus Hemorrhoid Procedures Hernia Repair Laparoscopic Appendectomy Proctosigmoidoscopy Small Bowel Resection Spleen Surgey Thyroid Gland Removal Tracheostomy Endoscopic Retrograde Cholangiopancreatography (ERCP) Gallbladder Removal Laparoscopic Gallbladder Removal
Conditions:
Abdominal Hernia Appendicitis Breast Disorders Cholelethiasis or Cholecystitis Hemorrhoids
Languages:
English Spanish
Description:
Dr. Gross graduated from the Eastern Virginia Medical School Medical College in 1996. He works in Greensboro, NC and specializes in General Surgery. Dr. Gross is affiliated with Moses H Cone Memorial Hospital and Wesley Long Hospital.
BayCare Medical GroupBayCare Medical Group Suncoast Medical Clinic 620 10 St N STE 2C, Saint Petersburg, FL 33705 7278247134 (phone), 7278248329 (fax)
Education:
Medical School University of Illinois, Chicago College of Medicine Graduated: 1981
Conditions:
Acute Conjunctivitis Cataract Glaucoma Keratitis
Languages:
English
Description:
Dr. Gross graduated from the University of Illinois, Chicago College of Medicine in 1981. He works in Saint Petersburg, FL and specializes in Ophthalmology. Dr. Gross is affiliated with St Anthonys Hospital.
Stark County Foot & Ankle Clinic 4503 Fulton Dr NW, Canton, OH 44718 3309564857 (phone), 3309564912 (fax)
Procedures:
Hallux Valgus Repair
Conditions:
Hallux Valgus Plantar Fascitis Tinea Pedis
Languages:
English
Description:
Dr. Gross works in Canton, OH and specializes in Podiatric Medicine. Dr. Gross is affiliated with Affinity Medical Center, Aultman Hospital and Mercy Medical Center.
Medical School Vanderbilt University School of Medicine Graduated: 1988
Languages:
English
Description:
Dr. Gross graduated from the Vanderbilt University School of Medicine in 1988. He works in Gadsden, AL and 3 other locations and specializes in Anesthesiology. Dr. Gross is affiliated with Gadsden Regional Medical Center, Marshall Medical Center South, Riverview Regional Medical Center and Stringfellow Memorial Hospital.
Dr. Gross graduated from the University of Michigan Medical School in 1972. He works in Edison, NJ and 2 other locations and specializes in Diagnostic Radiology and Radiology. Dr. Gross is affiliated with Robert Wood Johnson University Hospital Somerset.
IHI Power Services Corp. Oil & Energy · Nonclassifiable Establishments
95 Enterprise, Aliso Viejo, CA 92656 95 Enterprise Dr SUITE 300, Aliso Viejo, CA 92656 1 Metropolitan Sq, Saint Louis, MO 63102 11 Vl Franche, Dana Point, CA 92629
Steven F. Gross Principal
STEVEN F. GROSS, C.P.A., PC Accounting/Auditing/Bookkeeping
100 Oakley St, Cambridge, MD 21613
Steven M. Gross
HOPE FOR SURVIVING CHILDREN OF VIOLENT CRIME
Steven Gross Manager
South Orange County Community College District Junior College
PO Box 465, Tustin, CA 92781 Old Marine Corp Base, Tustin, CA 92781 7142581122
Steven B. Gross M
Family Guys LLC
3999 S Dobson Rd, Chandler, AZ 85248 10 Orion Way, Trabuco Canyon, CA 92679 25005 S Rangewood Dr, Chandler, AZ 85248 18435 E Purple Sage Dr, Queen Creek, AZ 85142