Steven Anil Nanda

US Patent:

7087385, Aug 8, 2006

Filed:

May 15, 2003

Appl. No.:

10/438803

Inventors:

Ned H. Kalin - Madison WI, US
Patrick Henry Roseboom - Madison WI, US
Steven Anil Nanda - Madison WI, US

Assignee:

Wisconsin Alumni Research Foundation - Madison WI

International Classification:

C12Q 1/68

US Classification:

435 6

Abstract:

Various human urocortin II promoter sequences are disclosed. Nucleic acids and host cells that contain the promoter sequences are also disclosed. Further disclosed are various methods involving the use of these sequences. Also disclosed are methods of modulating the activity of a human urocortin II promoter sequence and methods of modulating urocortin II expression in a cell.

US Patent:

7122650, Oct 17, 2006

Filed:

Oct 1, 2003

Appl. No.:

10/676526

Inventors:

Patrick H. Roseboom - Madison WI, US
Ned H. Kalin - Madison WI, US
Steven A. Nanda - Madison WI, US

Assignee:

Wisconsin Alumni Research Foundation - Madison WI

International Classification:

C07B 21/04
C12Q 1/68
C12N 1/00
C12N 15/00
C12N 15/09

US Classification:

536 234, 4353201, 435 6, 514 44

Abstract:

Various human corticotropin-releasing factor binding protein promoter sequences are disclosed. Nucleic acids and host cells that contain the promoter sequences are also disclosed. Further disclosed are various methods involving the use of these sequences.

US Patent:

7531356, May 12, 2009

Filed:

Sep 26, 2005

Appl. No.:

11/234916

Inventors:

Ned H. Kalin - Madison WI, US
Patrick H. Roseboom - Madison WI, US
Charles F. Landry - Madison WI, US
Steven A. Nanda - Madison WI, US

Assignee:

Wisconsin Alumni Research Foundation - Madison WI

International Classification:

C12N 15/85
C07H 21/04

US Classification:

435455, 536 241, 536 245

Abstract:

The DNA sequences of human and rat CRF receptor promoters are disclosed. Certain functional fragments of the human CRF receptor promoter are also disclosed. Further disclosed are a method of identifying functional fragments of human and rat CRF receptor promoters and a method of identifying agents that can alter the activity of the human or rat CRF receptor promoter.

US Patent:

20020032912, Mar 14, 2002

Filed:

Apr 30, 2001

Appl. No.:

09/847852

Inventors:

Ned Kalin - Madison WI, US
Patrick Roseboom - Madison WI, US
Charles Landry - Fitchburg WI, US
Steven Nanda - Madison WI, US

International Classification:

A01K067/00
G01N033/567

US Classification:

800/003000, 435/007210

Abstract:

A method for identifying agents that alter the activity of the promoter region of CRF receptor is disclosed. In one embodiment, the method comprises the steps of (a) obtaining a cell line or organism, wherein the cell line or organism comprises a nucleic acid sequence encoding a promoter sequence of a heterologous CRF receptor operably attached to a reporter gene and (b) introducing a test agent into the cell or transgenic animal and evaluating the expression of the reporter gene product compared to a control cell line or transgenic animal wherein the agent has not been introduced into the cell line or transgenic animal.

US Patent:

20030110521, Jun 12, 2003

Filed:

Nov 12, 2002

Appl. No.:

10/293702

Inventors:

Ned Kalin - Madison WI, US
Patrick Roseboom - Madison WI, US
Charles Landry - Madison WI, US
Steven Nanda - Madison WI, US

International Classification:

A01K067/00
C07H021/04
C12P021/02
C12N005/06
C07K014/705

US Classification:

800/008000, 435/069100, 435/320100, 435/325000, 530/350000, 536/023500

Abstract:

The DNA sequences of human and rat CRF receptor promoters are disclosed. Certain functional fragments of the human CRF receptor promoter are also disclosed. Further disclosed are a method of identifying functional fragments of human and rat CRF receptor promoters and a method of identifying agents that can alter the activity of the human or rat CRF receptor promoter.

US Patent:

20050042212, Feb 24, 2005

Filed:

Jul 22, 2004

Appl. No.:

10/896544

Inventors:

Steven Nanda - Middleton WI, US
Vaishali Bakshi - Madison WI, US
Patrick Roseboom - Madison WI, US
Ned Kalin - Madison WI, US

International Classification:

A61K038/47

US Classification:

424094610

Abstract:

A method of treating a patient is disclosed. In one embodiment, the method comprises the step of reducing the amount of mRNA encoding corticotropin-releasing factor receptor, wherein a portion of the mRNA encoding corticotropin-releasing factor receptor is destroyed and wherein the amount of corticotrophin releasing factor receptor is reduced.

US Patent:

20060281127, Dec 14, 2006

Filed:

Aug 15, 2006

Appl. No.:

11/504817

Inventors:

Ned Kalin - Madison WI, US
Patrick Roseboom - Madison WI, US
Steven Nanda - Madison WI, US

International Classification:

C12Q 1/68
C07H 21/04
C12P 21/06
C07K 14/705

US Classification:

435006000, 435069100, 435320100, 435325000, 530350000, 536023200

Abstract:

Various human urocortin II promoter sequences are disclosed. Nucleic acids and host cells that contain the promoter sequences are also disclosed. Further disclosed are various methods involving the use of these sequences. Also disclosed are methods of modulating the activity of a human urocortin II promoter sequence and methods of modulating urocortin II expression in a cell.

US Patent:

20080124315, May 29, 2008

Filed:

Jul 18, 2006

Appl. No.:

11/488276

Inventors:

Steven A. Nanda - Middleton WI, US
Vaishali P. Bakshi - Madison WI, US
Patrick H. Roseboom - Madison WI, US
Ned H. Kalin - Madison WI, US

International Classification:

A61K 38/47
A61P 1/00
A61P 1/04
A61P 9/00
A61K 38/48
A61P 25/24
A61K 38/46

US Classification:

424 9461, 424 946, 424 9463

Abstract:

A method of treating a patient is disclosed. In one embodiment, the method comprises the step of reducing the amount of mRNA encoding corticotropin-releasing factor receptor, wherein a portion of the mRNA encoding corticotropin-releasing factor receptor is destroyed and wherein the amount of corticotrophin releasing factor receptor is reduced.

Address:

16677 Bobcat Dr, Fort Myers, FL 33908

Phone:

6088337238

VIN:

WDBUF87X58B248390

Make:

MERCEDES B

Model:

E CLASS

Year:

2008