Terry H Shelley

US Patent:

6551291, Apr 22, 2003

Filed:

Aug 4, 1999

Appl. No.:

09/366914

Inventors:

Patrick S. Jensen - Cockeysville MD
Terry H. Shelley - Hampstead MD

Assignee:

Johns Hopkins University - Baltimore MD

International Classification:

A61M 3500

US Classification:

604294, 604289

Abstract:

In preferred aspects, the present invention features a non-traumatic cannula for use in connection with eye surgery, such as retinal tear and/or detachment surgery. The non-traumatic cannula of the present invention is particularly configured so as to minimize or avoid the potential for damage to the retina when infusing air or a gas therein. Related methods are also disclosed for infusing air during eye surgical procedures e. g. for treating a retinal tear or detachment and macular hole surgery. The method for infusing a fluid, such as a gas, into a patients eye during eye surgery includes flowing the fluid from a fluid source to the patients eye and diffusing the flowing fluid as it enters into the patient eye. Such a method further includes providing a non-traumatic cannula that is fluidly coupled to the fluid source, and which diffuses fluid exiting an end thereof. Thus, the fluid flowing out of the cannula is thereby diffusively infused.

US Patent:

6572608, Jun 3, 2003

Filed:

Apr 7, 2000

Appl. No.:

09/545143

Inventors:

Eric T. Lee - Emeryville CA 94608
Patrick S. Jensen - Owings Mills MD 21117
Terry H. Shelley - Hampstead MD 21074
Carl C. Awh - Nashville TN 37221
Michael D. Auld - Chesterfield MO 63005
Gregg D. Scheller - Wildwood MO 63038

International Classification:

A61B 1818

US Classification:

606 15, 606 4, 606 13, 606 78

Abstract:

A microsurgical laser probe is provided with a distal end portion of an optic fiber that projects from a tubular sleeve of the probe and can be caused to bend relative to the probe sleeve by manual manipulation of a mechanism on a handle of the probe.

US Patent:

6719750, Apr 13, 2004

Filed:

Jun 22, 2001

Appl. No.:

09/888092

Inventors:

Signe Erickson Varner - Los Angeles CA
Eugene DeJuan, Jr. - La Canada CA
Terry Shelley - Hampstead MD
Aaron Christopher Barnes - Oak Park CA
Mark Humayun - La Canada CA

Assignee:

The Johns Hopkins University - Baltimore MD

International Classification:

A61F 922

US Classification:

60489001, 424427, 606107

Abstract:

An therapeutic agent delivery device that can allows is particularly suitable for delivery of a therapeutic agent to limited access regions, such as the posterior chamber of the eye and inner ear. Preferred devices of the invention are minimally invasive, refillable and may be easily fixed to the treatment area. Preferred delivery devices of the invention also include those that comprise a non-linear shaped body member body housing one or more substances and a delivery mechanism for the sustained delivery of the one or more substances from the non-linear shaped body member to the patient.

US Patent:

7077848, Jul 18, 2006

Filed:

Mar 11, 2000

Appl. No.:

09/523767

Inventors:

Terry H. Shelley - Hampstead MD, US
Aaron C. Barnes - Columbia MD, US
Patrick S. Jensen - Cockeysville MD, US

Assignee:

John Hopkins University - Baltimore MD

International Classification:

A61F 11/00

US Classification:

606108, 606166

Abstract:

Featured are new methods for performing intra-ocular surgery that allow surgical personnel to access the intra-ocular volume to perform a surgical procedure or technique but which does not require the use of sutures to seal the sclera and/or conjunctiva following the procedure. The methods of the present invention generally include providing an entry alignment device and inserting the entry alignment device into an eye through both the conjunctiva and sclera so as to form an entry aperture that extends between the exterior of the eye and the intra-ocular volume within the eye. The provided alignment device is configured so as to form or provide an aperture or opening in each of the conjunctiva and sclera of the eye and to maintain these apertures or openings in each of the conjunctiva and sclera aligned during the surgical procedure so these apertures or openings form the entry aperture. In more particular aspects, the provided entry alignment device is sized such that when the entry alignment device is removed from the eye following the completion of the surgical procedure, the aperture or opening formed in the sclera seals without the use of sutures. In a more specific aspect of the present invention, the provided entry alignment device is sized such that the apertures or openings and thus the entry aperture are self sealing.

US Patent:

7217263, May 15, 2007

Filed:

Jan 3, 2001

Appl. No.:

09/754094

Inventors:

Mark S. Humayun - Timonium MD, US
Patrick S. Jensen - Issaquah WA, US
Terry H. Shelley - Hampstead MD, US
Gildo Y. Fujii - Baltimore MD, US
Hany S. Hamza - Cairo, EG
Aaron C. Barnes - Columbia MD, US
Eugene deJuan, Jr. - Phoenix MD, US

Assignee:

The Johns Hopkins University - Baltimore MD

International Classification:

A61M 25/00
A61M 5/32

US Classification:

604523, 604524, 604272

Abstract:

A microcatheter system that allows for vascular infusion into retinal veins for extended periods of time. The microcatheter system includes a flexible cannula that is inserted into the retinal vein lumen and that remains stably within the retinal vein lumen without being held by a robot, micromanipulator or similar holding devices. The microcatheter system is particularly suitable for the treatment of retinal venous occlusive disease.

US Patent:

7485113, Feb 3, 2009

Filed:

Jun 22, 2001

Appl. No.:

09/888079

Inventors:

Signe Erickson Varner - Los Angeles CA, US
Eugene Dejuan, Jr. - La Canada CA, US
Terry Harrison Shelley - Hampstead MD, US

Assignee:

Johns Hopkins University - Baltimore MD

International Classification:

A61M 31/00

US Classification:

604521, 604506

Abstract:

Devices and devices for the treatment of the eye are disclosed. Preferred devices of the invention include a piercing member that is inserted into the eye to create a pathway for a cannula. The cannula is slidably mounted to the piercing member and is adapted to reach a treatment site within the eye at which material is injected into and/or withdrawn from the eye. The outer diameter of the piercing member is small enough to allow for self-sealing of the insertion site of the device upon the device's withdrawal therefrom. Also disclosed are methods for the utilizing the devices to treat the eye.

US Patent:

7883717, Feb 8, 2011

Filed:

Jun 12, 2002

Appl. No.:

10/171406

Inventors:

Signe Erickson Varner - Los Angeles CA, US
Eugene Dejuan - La Canada CA, US
Aaron Christopher Barnes - Oak Park CA, US
Terry Harrison Shelley - Hampstead MD, US
Michael J. Cooney - Durham NC, US

Assignee:

Johns Hopkins University - Baltimore MD

International Classification:

A61F 2/00
A61K 9/00
A61F 13/00

US Classification:

424427, 424400, 424422, 424423

Abstract:

A delivery device that allows for the sustained release of an agent, particularly useful for the sustained release of a therapeutic agent to limited access regions, such as the posterior chamber of the eye and inner ear. The delivery device is minimally invasive, refillable and may be easily fixed to the treatment area. The delivery device includes a hollow body with an inlet port at its proximal end for insertion of the agent, a reservoir for holding the agent and a delivery mechanism for the sustained delivery of the agent from the reservoir to the patient.

US Patent:

8096972, Jan 17, 2012

Filed:

Dec 19, 2003

Appl. No.:

10/740698

Inventors:

Sign Erickson Varner - Los Angeles CA, US
Eugene Dejuan, Jr. - La Canada CA, US
Terry Shelley - Hampstead MD, US
Aaron Christopher Barnes - Oak Park CA, US
Mark Humayun - La Canada CA, US

Assignee:

Johns Hopkins University - Baltimore MD

International Classification:

A61M 31/00

US Classification:

604 9301, 60489001, 6048911, 604521

Abstract:

A therapeutic agent delivery device that is particularly suitable for delivery of a therapeutic agent to limited access regions, such as the posterior chamber of the eye and inner ear. Preferred devices of the invention are minimally invasive, refillable and may be easily fixed to the treatment area. Preferred delivery devices of the invention also include those that comprise a non-linear shaped body member housing one or more substances and a delivery mechanism for the sustained delivery of the one or more substances from the non-linear shaped body member to the patient.