Victor V Chernomordik

US Patent:

7302287, Nov 27, 2007

Filed:

Jun 27, 2005

Appl. No.:

11/168286

Inventors:

Amir H. Gandjbakhche - Potomac MD, US
David W. Hattery - Washington DC, US
Jim Mulshine - Bethesda MD, US
Paul Smith - Annapolis MD, US
Victor Chernomordik - Rockville MD, US
Edward Wellner - Fairfax VA, US

Assignee:

The United States of America as represented by the Department of Health and Human Services - Washington DC

International Classification:

A61B 5/00

US Classification:

600407, 600477, 600478

Abstract:

The invention provides a device and method for monitoring inflammation of the epithelium. The device consists of a head region, a handle region and an optical bundle. At least two of the optical fibers in the bundle are utilized as a source of radiation, these two fibers are at two different angles from normal. At least one of the other optical fibers is utilized as a detector for the reflected radiation, or alternatively an image guide can be used as the detector. The device of the invention can be part of an external or internal system that can include a light source, the device, a multiplexer, a spectrometer, and a computer for data analysis. The method of the invention allows for the detection and monitoring of general inflammation of the oral epithelium. The inflammation of the epithelium can be detected or monitored to diagnose diseases of the oral epithelium, monitor such diseases, monitor treatment of such diseases, or pre-screen for and monitor preventative treatments of such diseases.

US Patent:

20020107448, Aug 8, 2002

Filed:

Oct 5, 2001

Appl. No.:

09/972700

Inventors:

Amir Gandjbakhche - Potomac MD, US
David Hattery - Washington DC, US
Jim Mulshine - Bethesda MD, US
Paul Smith - Annapolis MD, US
Ernest Hawk - Marriottsville MD, US
Victor Chernomordik - Rockville MD, US
Edward Wellner - Fairfax VA, US
Alec Eidsath - Bethesda MD, US

International Classification:

A61B006/00

US Classification:

600/476000, 600/477000

Abstract:

The invention provides a device and method for monitoring inflammation of the epithelium. The device consists of a head region, a handle region and an optical bundle. At least two of the optical fibers in the bundle are utilized as a source of radiation, these two fibers are at two different angles from normal. At least one of the other optical fibers is utilized as a detector for the reflected radiation, or alternatively an image guide can be used as the detector. The device of the invention can be part of an external or internal system that can include a light source, the device, a multiplexer, a spectrometer, and a computer for data analysis. The method of the invention allows for the detection and monitoring of general inflammation of the oral epithelium. The inflammation of the epithelium can be detected or monitored to diagnose diseases of the oral epithelium, monitor such diseases, monitor treatment of such diseases, or pre-screen for and monitor preventative treatments of such diseases.

US Patent:

20050203354, Sep 15, 2005

Filed:

Apr 13, 2005

Appl. No.:

11/105180

Inventors:

Amir Gandjbakhche - Potomac MD, US
David Hattery - Washington DC, US
Jim Mulshine - Bethesda MD, US
Paul Smith - Annapolis MD, US
Victor Chernomordik - Rockville MD, US
Edward Wellner - Fairfax VA, US

Assignee:

Government of the U. S., Represented by the Secretary, Department of Health & Human Services - Washington DC

International Classification:

A61B005/00

US Classification:

600315000

Abstract:

The invention provides a device and method for monitoring inflammation of the epithelium. The device consists of a head region, a handle region and an optical bundle. At least two of the optical fibers in the bundle are utilized as a source of radiation, these two fibers are at two different angles from normal. At least one of the other optical fibers is utilized as a detector for the reflected radiation, or alternatively an image guide can be used as the detector. The device of the invention can be part of an external or internal system that can include a light source, the device, a multiplexer, a spectrometer, and a computer for data analysis. The method of the invention allows for the detection and monitoring of general inflammation of the oral epithelium. The inflammation of the epithelium can be detected or monitored to diagnose diseases of the oral epithelium, monitor such diseases, monitor treatment of such diseases, or pre-screen for and monitor preventative treatments of such diseases.

US Patent:

20150112136, Apr 23, 2015

Filed:

Apr 4, 2013

Appl. No.:

14/390354

Inventors:

- Bethesda MD, US
Victor Chernomordik - Rockville MD, US
Moinuddin Hassan - Bristow VA, US
Alexander Sviridov - Moscow, RU
Zachary Ulissi - Bethesda MD, US
Paul D. Smith - Annapolis MD, US
Albert C. Boccara - Paris, FR

Assignee:

The United States of America, as represented by the Sec. Dept. of Health and Human Services - Bethesda MD

International Classification:

A61B 1/303
A61B 1/04
A61B 1/00

US Classification:

600111

Abstract:

A polarization-based colposcopy apparatus includes a polarization exchanging beam splitter pair oriented so that s- and p-polarizations are exchanged. An optical flux from a specimen is directed through the pair, and orthogonal components thereof are alternately or selectively coupled to an array detector. The detected images are processed based on image correlations to reveal specimen structures.