Extreme Light Infrastructure Attosecond Light Pulse Source May 2016 - Oct 2019
Group Leader and Consultant-Ultrafast Dynamics and Reaction Control Group
Extreme Light Infrastructure May 2016 - Oct 2019
Group Leader-Terahertz Reaction Control Group
Extreme Light Infrastructure and University of Szeged Department of Optics and Quantumelectronics Jul 2014 - Dec 2014
Visiting Professor
Jul 2014 - Dec 2014
Associate Professor In Experimental Physical
Lawrence Berkeley National Laboratory Jan 2003 - Aug 2005
Postdoctoral Researcher
Education:
Kansas State University 1999 - 2002
Doctorates, Doctor of Philosophy, Chemistry
University of Szeged 1993 - 1998
Master of Science, Masters, Organic Chemistry
Skills:
Physical Chemistry Characterization Nanoparticles Spectroscopy Experimental Physical Chemistry Colloidal Synthesis Nanoparticle Synthesis Quantum Dots Magnetic Particles Doping Semiconductors Optical Spectroscopy Single Molecule Spectroscopy Terahertz Spectroscopy Laser Spectroscopy Xuv Spectroscopy Ir Spectroscopy Lab Management Instrumental Development Fund Raising Proposal Development Professional Training Higher Education Academic Writing Technical Leadership Technical Writing Critical Thinking Analytic Thinking Magnetic Particle Testing Software Development Chemical Kinetics Catalysis Heterogeneous Catalysis Combustion Synchrotron Experiments Magnetic Hyperthemia Undergraduate and Graduate Education Afm Nanomaterials Chemistry Science Materials Science Laboratory Reaction Kinetics Powder X Ray Diffraction Research Nanotechnology Inorganic Chemistry Surface Chemistry Proposal Writing
Interests:
Magnetic Hyperthermia Magneto Liposomes Education Environment Science and Technology Health
Stefan H. Bossmann - Manhattan KS, US Deryl Troyer - Manhattan KS, US Matthew T. Basel - Manhattan KS, US Thilani Nishanthika Samarakoon - Manhattan KS, US Hongwang Wang - Manhattan KS, US Viktor Chikan - Manhattan KS, US Franklin Orban Kroh - Wamego KS, US Olga Barbara Koper - Dublin OH, US Brandon Ray Walker - Wamego KS, US Xiaoxuan Leaym - Manhattan KS, US
Assignee:
NANOSCALE CORPORATION - Manhattan KS KANSAS STATE UNIVERSITY RESEARCH FOUNDATION - Manhattan KS
International Classification:
A61K 49/18 A61B 5/055
US Classification:
600420, 424 93, 424 932
Abstract:
The present invention provides multifunctional nanoplatforms for assessing the activity of a protease in vivo or in vitro, along with methods of imaging and detecting the presence of cancerous or precancerous tissues, and the therapeutic treatment thereof, including monitoring of treatment. The diagnostic nanoplatforms comprise nanoparticles and are linked to each other or other particles via an oligopeptide linkage that comprises a consensus sequence specific for the target protease. Cleavage of the sequence by the target protease can be detected using various sensors, and the diagnostic results can be correlated with cancer prognosis. Individual unlinked nanoplatforms are also adaptable for therapeutic hyperthermia treatment of the cancerous tissue.