Vincent C Henrich

US Patent:

8637237, Jan 28, 2014

Filed:

Oct 5, 2006

Appl. No.:

11/543682

Inventors:

Vincent C. Henrich - Greensboro NC, US
Cary Alan Weinberger - Carrboro NC, US

Assignee:

The University of North Carolina at Greensboro - Greensboro NC

International Classification:

C12Q 1/68
C12N 15/63
C07H 21/04
C12N 5/00

US Classification:

435 61, 435455, 536 234

Abstract:

Ecdysteroid action in and other insects is mediated by the dimerization of two nuclear receptors, the ecdysone receptor (EcR) and Ultraspiracle (USP), which regulate the transcription of target genes. Disclosed are nucleic acid constructs to identify insecticides having the ability to modify insect development and growth in a developmental stage-specific and/or species-specific manner.

US Patent:

20050049230, Mar 3, 2005

Filed:

Aug 27, 2004

Appl. No.:

10/929090

Inventors:

Vincent Henrich - Greensboro NC, US
Cary Weinberger - Carrboro NC, US

International Classification:

A01N045/00
C12Q001/68
G01N033/53

US Classification:

514169000, 435006000, 435007100

Abstract:

Disclosed are methods and systems for screening for compounds that act to modulate insect growth. Bioassays including cell culture and/or transgenic insects engineered with various components of the ecdysoid receptor (EcR) and/or the farsenoid-X receptor (RXR) systems to identify compounds that act as insecticides and/or hormone receptor activators are described. Also described are compounds, and compositions, identified as being putative insecticides based upon their ability to activate EcR and/or FXR mediated transcription.

US Patent:

20110207707, Aug 25, 2011

Filed:

Jul 26, 2010

Appl. No.:

12/843485

Inventors:

Vincent C. Henrich - Greensboro NC, US
Cary Alan Weinberger - Carrboro NC, US

International Classification:

A01N 45/00
C12Q 1/68
A01P 15/00

US Classification:

514179, 435 613

Abstract:

Disclosed are methods and systems for screening for compounds that act to modulate insect growth. Bioassays including cell culture and/or transgenic insects engineered with various components of the ecdysoid receptor (EcR) and/or the farsenoid-X receptor (RXR) systems to identify compounds that act as insecticides and/or hormone receptor activators are described. Also described are compounds, and compositions, identified as being putative insecticides based upon their ability to activate EcR and/or FXR mediated transcription.

US Patent:

20130196323, Aug 1, 2013

Filed:

Feb 1, 2013

Appl. No.:

13/757420

Inventors:

The University of North Carolina At Greensboro - Greensboro NC, US
Vincent C. Henrich - Greensboro NC, US

Assignee:

The University of North Carolina At Greensboro - Greensboro NC

International Classification:

C12Q 1/68
G01N 33/487

US Classification:

435 611, 436501, 977781, 977920

Abstract:

In one aspect, methods of nucleic acid analysis are described herein. In some embodiments, a method of nucleic acid analysis comprises providing a mixture of differing single-strand nucleic acid segments, including unamplified single-strand nucleic acid segments, combining the mixture of differing single-strand nucleic acid segments with a single-strand nucleic acid probe, contacting the mixture with a membrane comprising at least one nanopore, applying an electric field across the nanopore, and measuring change in current through the nanopore during one or more nucleic acid translocation events.

US Patent:

20130281315, Oct 24, 2013

Filed:

Apr 23, 2013

Appl. No.:

13/868148

Inventors:

MARINELLA G. SANDROS - GREENSBORO NC, US
VINCENT C. HENRICH - GREENSBORO NC, US
STEPHEN A. VANCE - SOPHIA NC, US

Assignee:

THE UNIVERSITY OF NORTH CAROLINA AT GREENSBORO - GREENSBORO NC

International Classification:

C12Q 1/68
G01N 33/566

US Classification:

506 9, 5303913

Abstract:

Described is a biointerface using near-infrared quantum dots for surface plasmon resonance imaging biosensors.