William R Brugge

US Patent:

20080300507, Dec 4, 2008

Filed:

Jan 30, 2006

Appl. No.:

11/883281

Inventors:

Stacy Figueredo - Arlington MA, US
William J. Fienup - St. Louis MO, US
Barry Kudrowitz - Cambridge MA, US
Jacob A. Wronski - Mississauga, CA
Alexander H. Slocum - Bow NH, US
William R. Brugge - Boston MA, US

Assignee:

The General Hospital Corporation - Boston MA

International Classification:

A61B 10/00

US Classification:

600567

Abstract:

A biopsy needle includes tissue capture elements within the needle lumen to help hold a tissue sample within the needle and maintain its integrity. According to one aspect, several flexible members form a structure that allows tissue to enter the lumen during advancement of the needle into tissue, and prevents the tissue sample from exiting the needle during retraction of the needle. The flexible members may, in some embodiments, include cutting edges configured to cut the tissue sample from the target tissue mass at the start of needle extraction.

US Patent:

20050256426, Nov 17, 2005

Filed:

May 12, 2005

Appl. No.:

11/128000

Inventors:

William Brugge - Boston MA, US

International Classification:

A61B010/00

US Classification:

600569000

Abstract:

A tissue sample collection device is disclosed which includes an elongated needle having opposed proximal and distal end portions and having an interior lumen extending therethrough, and a brush accommodated within the interior lumen of the needle for collecting tissue samples, wherein the brush is mounted for movement between a retracted position disposed within the interior lumen of the needle and a protracted position extending from the distal end portion of the needle to collect a tissue sample.

US Patent:

20180055991, Mar 1, 2018

Filed:

Oct 6, 2017

Appl. No.:

15/727015

Inventors:

Carl Magnus SCHOELLHAMMER - Somerville MA, US
Carlo Giovanni TRAVERSO - Newton MA, US
Avraham SCHROEDER - Binyamina, IL
Baris POLAT - Pittsburgh PA, US
Daniel BLANKSCHTEIN - Brookline MA, US
Robert S. LANGER - Newton MA, US
William BRUGGE - Boston MA, US

International Classification:

A61M 3/02
A61M 37/00
A61M 31/00

Abstract:

Apparatus, kits, and methods for administering a substance are presented. A device for administering a substance includes an elongated body having a proximal end and a distal end, the elongated body defining an internal chamber extending between the proximal end and the distal end to direct the substance to the distal end, the distal end to connect with a tip, the tip to be at least partially inserted into an orifice of a body lumen of a subject, the tip having a shape configured to reduce leakage of the substance from the orifice upon the at least partial insertion. The tip includes an opening to pass the substance from the internal chamber into the body lumen; and a transducer to emit an ultrasound wave from the tip into the body lumen, thereby administering the substance to tissue in the body lumen.