Yuriy Y Petrov

US Patent:

20120203101, Aug 9, 2012

Filed:

Jul 9, 2011

Appl. No.:

13/179482

Inventors:

Donald S. Prough - Galveston TX, US
Rinat O. Esenaliev - League City TX, US
Daneshvari R. Solanki - League City TX, US
Michael Kinsky - League City TX, US
Yuriy Petrov - Galveston TX, US
Irene Petrov - Galveston TX, US

Assignee:

BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM - Austin TX

International Classification:

A61M 16/04
A61B 6/00

US Classification:

600424

Abstract:

Indwelling medical apparatus including one optoacoustic discernible member or a plurality of optoacoustic discernible members and methods for optoacoustic guidance and confirmation of placement of optoacoustically discernible indwelling medical apparatus.

US Patent:

20140058253, Feb 27, 2014

Filed:

Apr 30, 2012

Appl. No.:

14/114454

Inventors:

Donald S. Prough - Galveston TX, US
Rinat O. Esenaliev - League City TX, US
Yuriy Petrov - Galveston TX, US
Irene Petrov - Galveston TX, US

Assignee:

BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM - Austin TX

International Classification:

A61B 5/06
A61B 1/06
A61M 16/04
A61B 5/00
A61B 1/07

US Classification:

600424

Abstract:

Medical apparatus are disclosed for optoacoustic monitoring of an indwelling unit of the apparatus, where the indwelling unit includes one or more optical components capable of directing pulsed light into an overlying tissue. The apparatus also include one or more acoustic components in contact with an exterior surface of the tissue to detect induced pressure waves producing an acoustic output analyzed with an optoacoustic unit to monitor and confirm proper placement of the indwelling unit. Methods for using the apparatus are also disclosed.

US Patent:

20080255433, Oct 16, 2008

Filed:

Apr 11, 2008

Appl. No.:

12/101891

Inventors:

Donald S. Prough - Galveston TX, US
Rinat O. Esenaliev - League City TX, US
Donald Deyo - Galveston TX, US
Yuriy Y. Petrov - Galveston TX, US
Irina Y. Petrova - Galveston TX, US

Assignee:

The Board of Regents of The University of Texas Syatem - Austin TX

International Classification:

A61B 5/145

US Classification:

600301, 600310

Abstract:

An optoacoustic technique for absolute, accurate, continuous, and real-time measurement of a variety of important diagnostic variables is disclosed, where the variables include: (1) noninvasive measurements of circulating blood volume (BV) and cardiac output (CO); (2) calculation from the measured variables of cardiac index (CI) and systemic oxygen delivery (DO); (3) concentrations of hemoglobin derivatives (e.g., carboxyhemoglobin [HbCO], reduced hemoglobin [Hb], oxygenated hemoglobin [HbOxy], and methemoglobin [HbMet]), total hemoglobin concentration [THb], concentrations of lactate, myoglobin, cholesterol, body pigments, and exogenous dyes; (4) content in tissues of water, fat, protein, calcium, and blood; as well as density of hard and soft tissues; and (5) accurate noninvasive measurement of blood pressure (or vascular pressure) in arteries, arterioles, veins, capillaries, using occlusion-induced changes in optoacoustic signal induced in blood circulating in the vessels. The optoacoustic technique can be used for single measurement, continuous measurement, or continuous monitoring of these variables.

US Patent:

20200345985, Nov 5, 2020

Filed:

May 3, 2019

Appl. No.:

16/402493

Inventors:

Yuriy Petrov - Galveston TX, US
Irene Petrov - Galveston TX, US
Rinat O. Esenaliev - League City TX, US

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

A61M 25/01
A61M 19/00
A61B 90/00

Abstract:

In one embodiment, a system for locating a tip of a catheter that has been inserted into a patient includes an implantable catheter having a distal tip, a pulsed light source that is co-located with the distal tip of the implantable catheter, the pulsed light source being configured to emit pulses of light into surrounding patient tissue, an optoacoustic sensor configured to be applied so a skin surface of the patient at a position proximate to the pulsed light source and to sense optoacoustic waves generated when the pulses of light are absorbed by the surrounding patient tissue, and an optoacoustic console configured to receive optoacoustic wave signals from the optoacoustic sensor and to display an indication of the optoacoustic wave signals to a medical professional to provide an indication of the location of the pulsed light source and, therefore, the distal tip of the implantable catheter.

US Patent:

20200337781, Oct 29, 2020

Filed:

Apr 24, 2019

Appl. No.:

16/393529

Inventors:

Yuriy Petrov - Galveston TX, US
Irene Petrov - Galveston TX, US
Rinat O. Esenaliev - League City TX, US

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

A61B 34/20
A61M 25/01
A61B 8/08

Abstract:

In one embodiment, a system for locating a tip of a catheter that has been inserted into a patient includes an implantable catheter having a distal tip, a pulsed light source that is co-located with the distal tip of the implantable catheter, the pulsed light source being configured to emit pulses of light into surrounding patient tissue, an optoacoustic sensor configured to be applied so a skin surface of the patient at a position proximate to the pulsed light source and to sense optoacoustic waves generated when the pulses of light are absorbed by the surrounding patient tissue, and an optoacoustic console configured to receive optoacoustic wave signals from the optoacoustic sensor and to display an indication of the optoacoustic wave signals to a medical professional to provide an indication of the location of the pulsed light source and, therefore, the distal tip of the implantable catheter.

US Patent:

20190231239, Aug 1, 2019

Filed:

Sep 12, 2017

Appl. No.:

16/332538

Inventors:

Donald S. Prough - Galveston TX, US
Michael P Kinsky - League City TX, US
Rinat O. Esenaliev - Galveston TX, US
Irene Y. Petrov - Galveston TX, US
Yuriy Petrov - Galveston TX, US

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

A61B 5/145
A61B 5/00
A61B 8/08
A61B 8/00

Abstract:

Apparatus and methods are described for ultrasound guided optoacoustic monitoring to provide diagnostic information for many clinical applications blood oxygenation in blood vessels and in tissues including for early diagnosis and management of circulatory shock (including that induced by hemorrhage). In certain embodiments provided herein, methods and apparatus for optoacoustics for measurement of blood oxygenation in the innominate vein are provided.

US Patent:

20190216376, Jul 18, 2019

Filed:

Jan 22, 2019

Appl. No.:

16/253678

Inventors:

- Galveston TX, US
- Austin TX, US
Yuriy PETROV - Galveston TX, US
Irene PETROV - Galveston TX, US
George SAADE - Houston TX, US
Gayle L. OLSON - Galveston TX, US
Tommy G. COOPER - Friendswood TX, US

International Classification:

A61B 5/145
A61B 5/00
A61B 5/1464
A61B 5/1459
A61B 5/1455

Abstract:

Optoacoustic diagnostic systems, devices, and methods are described. A system may comprise a console unit and a handheld probe. The console unit comprises a controller, a processor, a photodiode array, an acoustic processing subsystem, and a cooling subsystem. The probe directs light signals from the photodiode array to patient tissue. The light signals each have different wavelengths selected based on the physiological parameter of interest. The probe further comprises an acoustic transducer that receives acoustic signals generated in response to the directed light signals. The probe may comprise a finger-held working end that can be directed to the skull of a fetus within the uterus during labor. The probe can then accurately determine blood oxygenation of the fetus to determine if a caesarian section is necessary.

US Patent:

20190142316, May 16, 2019

Filed:

Jan 16, 2019

Appl. No.:

16/249180

Inventors:

Rinat O. Esenaliev - League City TX, US
Donald S. Prough - Galveston TX, US
Yuriy Petrov - Galveston TX, US
Irene Y. Petrov - Galveston TX, US
C. Joan Richardson - Galveston TX, US

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

A61B 5/1455
A61B 5/00
A61B 5/145

Abstract:

Disclosed herein are systems and methods for monitoring one or more of cerebral oxygenation and total hemoglobin concentration that can be used to perform accurate, noninvasive measurement of cerebral venous blood oxygen saturation (oxygenation) in neonatal patients. A neonatal cerebral oxygenation detection apparatus comprises a wearable support having a light emitter and an acoustic sensor coupled thereto. The wearable support can be secured onto a head of an infant, and the light emitter can be configured to emit a light toward a superior sagittal sinus of the infant's head. The acoustic sensor can be configured to detect acoustic pressure generated by blood in the superior sagittal sinus when the superior sagittal sinus blood absorbs the light. Cerebral oxygenation and/or total hemoglobin concentration can be determined based on the acoustic pressure detected by the acoustic detector.