Andrzej Jesmanowicz

US Patent:

7328054, Feb 5, 2008

Filed:

Apr 9, 2003

Appl. No.:

10/410710

Inventors:

Andrzej Jesmanowicz - Wauwatosa WI, US

Assignee:

The MCW Research Foundation, Inc. - Milwaukee WI

International Classification:

A61B 5/05

US Classification:

600410, 600419, 600407

Abstract:

A perfusion image is produced by acquiring a series of time course MR images from an imaging slice. During the acquisition spins flowing into the slice are repeatedly tagged with an RF tagging pulse having a flip angle that is modulated according to a tagging pattern. Voxels in the series of reconstructed MR images having signals which vary according to the tagging pattern indicate perfusion. Perfusion images indicating either flow or velocity are produced.

US Patent:

7395108, Jul 1, 2008

Filed:

May 12, 2004

Appl. No.:

10/843940

Inventors:

Vinai Roopchansingh - Milwaukee WI, US
Robert W. Cox - Bethesda MD, US
Andrzej Jesmanowicz - Wauwatosa WI, US
James S. Hyde - Dousman WI, US

International Classification:

A61B 5/05
G01V 3/00

US Classification:

600410, 324307

Abstract:

A technique for acquiring magnetic field maps simultaneously with the images they affect allows improved correction of shimming and/or geometric distortions in the image and allows imaging techniques where subject motion is inevitable or required.

US Patent:

7807474, Oct 5, 2010

Filed:

Mar 23, 2007

Appl. No.:

11/690193

Inventors:

Andrzej Jesmanowicz - Wauwatosa WI, US

Assignee:

MCW Research Foundation, Inc. - Milwaukee WI

International Classification:

G01N 24/00

US Classification:

436173, 600410, 324307

Abstract:

A magnetic resonance imaging (MRI) system includes a transmitter that produces an RF excitation pulse that is applied to a subject positioned in the MRI system to induce emission of at least one of an NMR signal and an ESR signal therefrom, and that produces a reference signal indicative of the phase of the RF excitation pulse. A first analog-to-digital converter has an input for receiving the reference signal that is synchronous with the RF excitation pulse. One or more additional analog-to-digital converters/processors have inputs for receiving the at least one of NMR signals and ESR signals produced by a subject placed in the MRI system and produce one or more complex digital signals therefrom. A normalizer is connected to receive and normalize the digital reference signal and a mixer is connected to receive the normalized digital reference signal and the digital signal. Accordingly, the mixer is operable to multiply the normalized complex digital reference signal with the complex digital signal.

US Patent:

8021892, Sep 20, 2011

Filed:

Aug 31, 2010

Appl. No.:

12/872641

Inventors:

Andrzej Jesmanowicz - Wauwatosa WI, US

Assignee:

MCW Research Foundation Inc. - Milwaukee WI

International Classification:

G01R 33/44
G06G 7/12

US Classification:

436173, 600410, 324322, 327355

Abstract:

A magnetic resonance imaging (MRI) system includes a transmitter that produces an RF excitation pulse that is applied to a subject positioned in the MRI system to induce emission of at least one of an NMR signal and an ESR signal therefrom, and that produces a reference signal indicative of the phase of the RF excitation pulse. A first analog-to-digital converter has an input for receiving the reference signal that is synchronous with the RF excitation pulse. One or more additional analog-to-digital converters/processors have inputs for receiving the at least one of NMR signals and ESR signals produced by a subject placed in the MRI system and produce one or more complex digital signals therefrom. A normalizer is connected to receive and normalize the digital reference signal and a mixer is connected to receive the normalized digital reference signal and the digital signal. Accordingly, the mixer is operable to multiply the normalized complex digital reference signal with the complex digital signal.

US Patent:

20010056231, Dec 27, 2001

Filed:

Mar 13, 2001

Appl. No.:

09/804934

Inventors:

Andrzej Jesmanowicz - Wauwatosa WI, US
James Hyde - Dousman WI, US
Bharat Biswal - Milwaukee WI, US

International Classification:

A61B005/055

US Classification:

600/410000

Abstract:

An EPI pulse sequence is performed by an NMR system which acquires images of the brain over a time interval during which the subject performs a function or is stimulated in a pattern. The voxel size of acquired images corresponds to the anatomy of cortical microcirculation structures which range from 1 to 2 mm along all three axes. A centric view order is employed and one-half of k-space is sampled to reduce scan time for each image.

US Patent:

20120319686, Dec 20, 2012

Filed:

Feb 25, 2011

Appl. No.:

13/581209

Inventors:

Andrzej Jesmanowicz - Brookfield WI, US
James S. Hyde - Dousman WI, US

International Classification:

G01R 33/56

US Classification:

324309

Abstract:

A method for reconstructing a plurality of images depicting a subject from image data that is simultaneously acquired from a corresponding plurality of slice locations with a magnetic resonance imaging (MRI] system is provided. Image data is acquired following the application of radio frequency (RF] energy to the plurality of slice locations. The RF energy is tailored to provide a different phase to each of the plurality of slice locations. Reference image data is also acquired for each slice location following the application of RF energy that has the same phase as is used to excite the respective slice location for the acquisition of the image data. Aliased images are reconstructed from the image data, and reference images are reconstructed from the reference image data. Using both of these image sets, an unaliased image is produced for each of the plurality of slice locations.

US Patent:

56033222, Feb 18, 1997

Filed:

Dec 27, 1994

Appl. No.:

8/365371

Inventors:

Andrzej Jesmanowicz - Wauwatosa WI
Peter A. Bandettini - Whitefish Bay WI
James S. Hyde - Dousman WI
Eric C. Wong - Wauwatosa WI

Assignee:

MCW Research Foundation - Milwaukee WI

International Classification:

A61B 5055

US Classification:

1286532

Abstract:

An EPI pulse sequence is performed by an NMR system which acquires 128 images of the brain over a time interval during which the subject performs a function or is stimulated. The acquired time course NMR data is displayed in different ways for analysis. Four different methods for producing brain function images from the NMR data are described.

US Patent:

47257792, Feb 16, 1988

Filed:

Aug 15, 1986

Appl. No.:

6/897165

Inventors:

James S. Hyde - Dousman WI
Wojciech Froncisz - Krakow, PL
Andrzej Jesmanowicz - Wauwatosa WI

Assignee:

MCW Research Foundation, Inc. - Milwaukee WI

International Classification:

G01R 3320

US Classification:

324318

Abstract:

A local coil for use in NMR imaging includes a pair of loop-gap resonators which are geometrically arranged to be intrinsically isolated. The local coil also includes passive decoupling means to completely decouple the local coil during excitation. In a first embodiment, the pair of loop-gap resonators are disposed axially and the passive decoupling means comprises a pair of back-to-back diodes across the loop-gap resonators. In a second embodiment, the pair of loop-gap resonators are disposed in a plane and the passive decoupling means comprises two single turn loops inside each loop-gap resonator with back-to-back diodes across an open segment of each single turn loop. During excitation, the diodes fire thereby lowering the Q and shifting the resonant frequency of the local coil. Using a combination of intrinsic isolation and passive decoupling, the local coil is completely decoupled from the excitation field. During periods of reception, the diodes revert to their nonconducting state and the intrinsic isolation continues to function providing some degree of noise immunity for the local coil.